gout Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi. (Experimental Factor Ontology, EFO_0004274)
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Genes

40 genes co-occuring with the biological term gout in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADRB3 adrenoceptor beta 3
ALPK1 alpha-kinase 1
CST3 cystatin C
CTSB cathepsin B
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
GCKR glucokinase (hexokinase 4) regulator
HNF1B HNF1 homeobox B
HPRT1 hypoxanthine phosphoribosyltransferase 1
IL10 interleukin 10
IL12B interleukin 12B
IL18 interleukin 18
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
KDR kinase insert domain receptor
LRP2 low density lipoprotein receptor-related protein 2
LRRC16A leucine rich repeat containing 16A
MAOA monoamine oxidase A
NLRP3 NLR family, pyrin domain containing 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PKD2 polycystic kidney disease 2 (autosomal dominant)
PON1 paraoxonase 1
PRKG2 protein kinase, cGMP-dependent, type II
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC17A1 solute carrier family 17 (organic anion transporter), member 1
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
TEC tec protein tyrosine kinase
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UMOD uromodulin