gpi anchor biosynthetic process Gene Set
Dataset
GO Biological Process Annotations 2015
Category
structural or functional annotations
Type
biological process
Description
The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage. (Gene Ontology , GO_0006506 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0006506
Similar Terms
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Genes
20 genes participating in the gpi anchor biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.
Symbol
Name
CWH43
cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPM2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPM3
dolichyl-phosphate mannosyltransferase polypeptide 3
MPPE1
metallophosphoesterase 1
PGAP2
post-GPI attachment to proteins 2
PGAP3
post-GPI attachment to proteins 3
PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
PIGC
phosphatidylinositol glycan anchor biosynthesis, class C
PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
PIGG
phosphatidylinositol glycan anchor biosynthesis, class G
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
PIGL
phosphatidylinositol glycan anchor biosynthesis, class L
PIGO
phosphatidylinositol glycan anchor biosynthesis, class O
PIGU
phosphatidylinositol glycan anchor biosynthesis, class U
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
PYURF
PIGY upstream reading frame
