| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the gramine-2143 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APP | amyloid beta (A4) precursor protein |
| ATP9B | ATPase, class II, type 9B |
| B9D2 | B9 protein domain 2 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCDC57 | coiled-coil domain containing 57 |
| CCNK | cyclin K |
| CD200 | CD200 molecule |
| CD47 | CD47 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| COL10A1 | collagen, type X, alpha 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CPTP | ceramide-1-phosphate transfer protein |
| CREM | cAMP responsive element modulator |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FAM105A | family with sequence similarity 105, member A |
| FAM65B | family with sequence similarity 65, member B |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GK3P | glycerol kinase 3 pseudogene |
| GPR135 | G protein-coupled receptor 135 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| H2AFX | H2A histone family, member X |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIC2 | hypermethylated in cancer 2 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXA10 | homeobox A10 |
| HRH2 | histamine receptor H2 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KIAA1109 | KIAA1109 |
| KLF12 | Kruppel-like factor 12 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LENEP | lens epithelial protein |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NMT2 | N-myristoyltransferase 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB3D | RAB3D, member RAS oncogene family |
| RANBP3 | RAN binding protein 3 |
| RDX | radixin |
| RPS28 | ribosomal protein S28 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SEC24A | SEC24 family member A |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPHK2 | sphingosine kinase 2 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| THAP10 | THAP domain containing 10 |
| THY1 | Thy-1 cell surface antigen |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TRIM25 | tripartite motif containing 25 |
| TRIM3 | tripartite motif containing 3 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACPP | acid phosphatase, prostate |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CEP97 | centrosomal protein 97kDa |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| COPS7B | COP9 signalosome subunit 7B |
| CORT | cortistatin |
| DAP | death-associated protein |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DOK5 | docking protein 5 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DUSP8 | dual specificity phosphatase 8 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA3 | ephrin-A3 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM57A | family with sequence similarity 57, member A |
| FBXO46 | F-box protein 46 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOXC1 | forkhead box C1 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GALE | UDP-galactose-4-epimerase |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GSTT1 | glutathione S-transferase theta 1 |
| HIRA | histone cell cycle regulator |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4D | histone cluster 1, H4d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HPSE | heparanase |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIF24 | kinesin family member 24 |
| KIFC1 | kinesin family member C1 |
| KLK5 | kallikrein-related peptidase 5 |
| LIMD2 | LIM domain containing 2 |
| LOC157562 | uncharacterized LOC157562 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP1S | microtubule-associated protein 1S |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAPD7 | PAP associated domain containing 7 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| POLL | polymerase (DNA directed), lambda |
| PRAMEF11 | PRAME family member 11 |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RPAP1 | RNA polymerase II associated protein 1 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAGLN | transgelin |
| TCTN2 | tectonic family member 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM127 | transmembrane protein 127 |
| TMEM180 | transmembrane protein 180 |
| TMEM212 | transmembrane protein 212 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UCN | urocortin |
| USP19 | ubiquitin specific peptidase 19 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF215 | zinc finger protein 215 |
| ZNF665 | zinc finger protein 665 |
| ZNF747 | zinc finger protein 747 |
| ZNF749 | zinc finger protein 749 |