gramine-2799 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the gramine-2799 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADAM12 ADAM metallopeptidase domain 12
ADCK2 aarF domain containing kinase 2
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C1 aldo-keto reductase family 1, member C1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANGPT4 angiopoietin 4
AOC3 amine oxidase, copper containing 3
APOE apolipoprotein E
ARL4C ADP-ribosylation factor-like 4C
ARNT aryl hydrocarbon receptor nuclear translocator
AVPR1B arginine vasopressin receptor 1B
BAHCC1 BAH domain and coiled-coil containing 1
C14ORF79 chromosome 14 open reading frame 79
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN9 calpain 9
CD53 CD53 molecule
CD8A CD8a molecule
CGA glycoprotein hormones, alpha polypeptide
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTSF cathepsin F
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DICER1 dicer 1, ribonuclease type III
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLK2 delta-like 2 homolog (Drosophila)
DMTN dematin actin binding protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP9 dual specificity phosphatase 9
EXD3 exonuclease 3'-5' domain containing 3
FFAR2 free fatty acid receptor 2
GFER growth factor, augmenter of liver regeneration
GK glycerol kinase
GP2 glycoprotein 2 (zymogen granule membrane)
GPC3 glypican 3
GPR22 G protein-coupled receptor 22
GZMK granzyme K (granzyme 3; tryptase II)
HAL histidine ammonia-lyase
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HYAL3 hyaluronoglucosaminidase 3
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIAA0754 KIAA0754
KIAA1024 KIAA1024
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT6B keratin 6B, type II
LAMC2 laminin, gamma 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LTK leukocyte receptor tyrosine kinase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K7 mitogen-activated protein kinase kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP2 matrix metallopeptidase 2
MST1L macrophage stimulating 1-like
MST1R macrophage stimulating 1 receptor
MYOF myoferlin
MZF1 myeloid zinc finger 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PADI1 peptidyl arginine deiminase, type I
PALMD palmdelphin
PAX5 paired box 5
PCDH1 protocadherin 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM7 PDZ and LIM domain 7 (enigma)
RAP2B RAP2B, member of RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETN resistin
RHOH ras homolog family member H
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SFRP4 secreted frizzled-related protein 4
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
STMN3 stathmin-like 3
TIMELESS timeless circadian clock
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TMEM63A transmembrane protein 63A
TMPRSS6 transmembrane protease, serine 6
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIM2 tripartite motif containing 2
TTLL1 tubulin tyrosine ligase-like family member 1
VIM vimentin
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPL1 zinc finger protein-like 1
ZNF230 zinc finger protein 230
ZNF507 zinc finger protein 507
ZNF771 zinc finger protein 771
ZSWIM1 zinc finger, SWIM-type containing 1
ZYX zyxin

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD17B abhydrolase domain containing 17B
ACSF2 acyl-CoA synthetase family member 2
AFAP1 actin filament associated protein 1
AGO1 argonaute RISC catalytic component 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
APOC1 apolipoprotein C-I
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BCL9 B-cell CLL/lymphoma 9
BCOR BCL6 corepressor
BCORL1 BCL6 corepressor-like 1
C16ORF45 chromosome 16 open reading frame 45
C19ORF40 chromosome 19 open reading frame 40
CA11 carbonic anhydrase XI
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMTA2 calmodulin binding transcription activator 2
CDK3 cyclin-dependent kinase 3
CGREF1 cell growth regulator with EF-hand domain 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
COPZ2 coatomer protein complex, subunit zeta 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNM1 dynamin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ERCC4 excision repair cross-complementation group 4
FMOD fibromodulin
GINS4 GINS complex subunit 4 (Sld5 homolog)
GK3P glycerol kinase 3 pseudogene
GMIP GEM interacting protein
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
HIST2H2AA3 histone cluster 2, H2aa3
IL17RA interleukin 17 receptor A
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBTD1 mbt domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFSD11 major facilitator superfamily domain containing 11
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGC12488
MKNK2 MAP kinase interacting serine/threonine kinase 2
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPY1R neuropeptide Y receptor Y1
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NXPE3 neurexophilin and PC-esterase domain family, member 3
OGFRL1 opioid growth factor receptor-like 1
OSMR oncostatin M receptor
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAIP2B poly(A) binding protein interacting protein 2B
PARP12 poly (ADP-ribose) polymerase family, member 12
PDZK1 PDZ domain containing 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G10 phospholipase A2, group X
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PP14571 uncharacterized LOC100130449
PRR14L proline rich 14-like
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRU protein tyrosine phosphatase, receptor type, U
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF123 ring finger protein 123
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC12A9 solute carrier family 12, member 9
SMA4 glucuronidase, beta pseudogene
SOWAHC sosondowah ankyrin repeat domain family member C
SSBP3 single stranded DNA binding protein 3
STEAP3 STEAP family member 3, metalloreductase
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TMEM62 transmembrane protein 62
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
VEZT vezatin, adherens junctions transmembrane protein
XK X-linked Kx blood group
ZBTB3 zinc finger and BTB domain containing 3
ZNF160 zinc finger protein 160
ZNF165 zinc finger protein 165
ZNF611 zinc finger protein 611
ZNF639 zinc finger protein 639
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF768 zinc finger protein 768
ZNF778 zinc finger protein 778
ZNF862 zinc finger protein 862