| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the gramine-4118 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADCK2 | aarF domain containing kinase 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ARG1 | arginase 1 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CALD1 | caldesmon 1 |
| CD8A | CD8a molecule |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN17 | claudin 17 |
| COL4A4 | collagen, type IV, alpha 4 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRNN | cornulin |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| FBXO40 | F-box protein 40 |
| FLT4 | fms-related tyrosine kinase 4 |
| FST | follistatin |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GSTM5 | glutathione S-transferase mu 5 |
| HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled |
| IL1RN | interleukin 1 receptor antagonist |
| KIAA0319L | KIAA0319-like |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL3 | lysyl oxidase-like 3 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRRC20 | leucine rich repeat containing 20 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MECOM | MDS1 and EVI1 complex locus |
| MED25 | mediator complex subunit 25 |
| MTSS1L | metastasis suppressor 1-like |
| MUC3B | mucin 3B, cell surface associated |
| MYCNOS | MYCN opposite strand |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NOL10 | nucleolar protein 10 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDLIM5 | PDZ and LIM domain 5 |
| PDPN | podoplanin |
| PIP | prolactin-induced protein |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PXN | paxillin |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB3A | RAB3A, member RAS oncogene family |
| RASA3 | RAS p21 protein activator 3 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGCC | regulator of cell cycle |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SAFB2 | scaffold attachment factor B2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SH3BP2 | SH3-domain binding protein 2 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPAG8 | sperm associated antigen 8 |
| SPATA1 | spermatogenesis associated 1 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPRR2B | small proline-rich protein 2B |
| STIM1 | stromal interaction molecule 1 |
| SYT5 | synaptotagmin V |
| TCF3 | transcription factor 3 |
| TCHH | trichohyalin |
| TDRD3 | tudor domain containing 3 |
| TEF | thyrotrophic embryonic factor |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMPRSS15 | transmembrane protease, serine 15 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM3 | tripartite motif containing 3 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTC39A | tetratricopeptide repeat domain 39A |
| UBXN1 | UBX domain protein 1 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WSCD1 | WSC domain containing 1 |
| ZNF235 | zinc finger protein 235 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARMC7 | armadillo repeat containing 7 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CCDC69 | coiled-coil domain containing 69 |
| CCNO | cyclin O |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD82 | CD82 molecule |
| CES3 | carboxylesterase 3 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FAM46C | family with sequence similarity 46, member C |
| FANCE | Fanconi anemia, complementation group E |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H4D | histone cluster 1, H4d |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXC10 | homeobox C10 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0125 | KIAA0125 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MDM4 | MDM4, p53 regulator |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHA6 | protocadherin alpha 6 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| REEP4 | receptor accessory protein 4 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF31 | ring finger protein 31 |
| RPL10L | ribosomal protein L10-like |
| S100A4 | S100 calcium binding protein A4 |
| S100A6 | S100 calcium binding protein A6 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SP1 | Sp1 transcription factor |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAOK1 | TAO kinase 1 |
| TEP1 | telomerase-associated protein 1 |
| TEX40 | testis expressed 40 |
| TFF2 | trefoil factor 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TOM1 | target of myb1 (chicken) |
| TRIM16 | tripartite motif containing 16 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| ULBP2 | UL16 binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| UPK2 | uroplakin 2 |
| WDR25 | WD repeat domain 25 |
| WDR76 | WD repeat domain 76 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
