granzyme-mediated apoptotic signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. (Gene Ontology, GO_0008626)
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5 genes participating in the granzyme-mediated apoptotic signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
LAMP1 lysosomal-associated membrane protein 1
SRGN serglycin
UBE4B ubiquitination factor E4B