graves disease Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland. (Human Disease Ontology, DOID_12361)
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Genes

58 genes associated with the disease graves disease in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C4A complement component 4A (Rodgers blood group)
C6ORF10 chromosome 6 open reading frame 10
CD274 CD274 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
ESR2 estrogen receptor 2 (ER beta)
FCRL3 Fc receptor-like 3
GC group-specific component (vitamin D binding protein)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL10 interleukin 10
IL13 interleukin 13
IL16 interleukin 16
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL3 interleukin 3
IL4 interleukin 4
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SCGB3A2 secretoglobin, family 3A, member 2
SELE selectin E
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
THRB thyroid hormone receptor, beta
TNF tumor necrosis factor
TP53 tumor protein p53
TSHR thyroid stimulating hormone receptor
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1