grb2 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description growth factor receptor-bound protein 2|The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2885)
Similar Terms
Downloads & Tools

Genes

125 proteins co-occuring with the biological term grb2 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACP1 acid phosphatase 1, soluble
ADAM12 ADAM metallopeptidase domain 12
ADAM15 ADAM metallopeptidase domain 15
AKT1 v-akt murine thymoma viral oncogene homolog 1
APP amyloid beta (A4) precursor protein
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
AXL AXL receptor tyrosine kinase
BCR breakpoint cluster region
BLNK B-cell linker
C6ORF25 chromosome 6 open reading frame 25
CALD1 caldesmon 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD19 CD19 molecule
CD22 CD22 molecule
CD28 CD28 molecule
CD300LF CD300 molecule-like family member f
CD79A CD79a molecule, immunoglobulin-associated alpha
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTTN cortactin
DCC DCC netrin 1 receptor
DNM1 dynamin 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
EGFR epidermal growth factor receptor
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHB3 EPH receptor B3
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ETV6 ets variant 6
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FOXO3 forkhead box O3
FRS2 fibroblast growth factor receptor substrate 2
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAREM GRB2 associated, regulator of MAPK1
GCSAM germinal center-associated, signaling and motility
GRB2 growth factor receptor-bound protein 2
GSK3B glycogen synthase kinase 3 beta
IL2RB interleukin 2 receptor, beta
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS4 insulin receptor substrate 4
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JUN jun proto-oncogene
KDR kinase insert domain receptor
KIDINS220 kinase D-interacting substrate, 220kDa
KIRREL kin of IRRE like (Drosophila)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEPR leptin receptor
LIME1 Lck interacting transmembrane adaptor 1
LY6G6F lymphocyte antigen 6 complex, locus G6F
LY9 lymphocyte antigen 9
MAP2 microtubule-associated protein 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MED28 mediator complex subunit 28
MET MET proto-oncogene, receptor tyrosine kinase
MPL MPL proto-oncogene, thrombopoietin receptor
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MST1R macrophage stimulating 1 receptor
MUC1 mucin 1, cell surface associated
NEU3 sialidase 3 (membrane sialidase)
NOX4 NADPH oxidase 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSMR oncostatin M receptor
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRH protein tyrosine phosphatase, receptor type, H
PTPRO protein tyrosine phosphatase, receptor type, O
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RET ret proto-oncogene
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SH2B3 SH2B adaptor protein 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SIT1 signaling threshold regulating transmembrane adaptor 1
SKAP1 src kinase associated phosphoprotein 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
SYK spleen tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THEMIS2 thymocyte selection associated family member 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TOM1L1 target of myb1 (chicken)-like 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa