griseofulvin-2293 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the griseofulvin-2293 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACPP acid phosphatase, prostate
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AIM2 absent in melanoma 2
AMN amnion associated transmembrane protein
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APOL6 apolipoprotein L, 6
ARMC4 armadillo repeat containing 4
BCAN brevican
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BDKRB2 bradykinin receptor B2
BTG2 BTG family, member 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF66 chromosome 19 open reading frame 66
C1QB complement component 1, q subcomponent, B chain
CABP2 calcium binding protein 2
CCKBR cholecystokinin B receptor
CCL16 chemokine (C-C motif) ligand 16
CD300A CD300a molecule
CD8A CD8a molecule
CHN2 chimerin 2
CPB1 carboxypeptidase B1 (tissue)
DNAH17 dynein, axonemal, heavy chain 17
DSC2 desmocollin 2
EFNB3 ephrin-B3
EN2 engrailed homeobox 2
ERC1 ELKS/RAB6-interacting/CAST family member 1
FBLN1 fibulin 1
FCGBP Fc fragment of IgG binding protein
FLRT2 fibronectin leucine rich transmembrane protein 2
GSTP1 glutathione S-transferase pi 1
GSTTP1 glutathione S-transferase theta pseudogene 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC7 histone deacetylase 7
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HRG histidine-rich glycoprotein
ICOSLG inducible T-cell co-stimulator ligand
IFI35 interferon-induced protein 35
IGLJ3 immunoglobulin lambda joining 3
IL1A interleukin 1, alpha
KLHL35 kelch-like family member 35
KMT2A lysine (K)-specific methyltransferase 2A
KREMEN2 kringle containing transmembrane protein 2
KRT83 keratin 83, type II
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAX1 lymphocyte transmembrane adaptor 1
LDB3 LIM domain binding 3
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAP2K5 mitogen-activated protein kinase kinase 5
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
NOV nephroblastoma overexpressed
NPR1 natriuretic peptide receptor 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTF3 neurotrophin 3
OLAH oleoyl-ACP hydrolase
PDE4D phosphodiesterase 4D, cAMP-specific
PEAK1 pseudopodium-enriched atypical kinase 1
PILRA paired immunoglobin-like type 2 receptor alpha
POU4F1 POU class 4 homeobox 1
PRKCQ protein kinase C, theta
PRKG2 protein kinase, cGMP-dependent, type II
PTGDR2 prostaglandin D2 receptor 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM19 RNA binding motif protein 19
RTN2 reticulon 2
SAMD4A sterile alpha motif domain containing 4A
SBNO2 strawberry notch homolog 2 (Drosophila)
SIT1 signaling threshold regulating transmembrane adaptor 1
SKIL SKI-like proto-oncogene
SLC35G2 solute carrier family 35, member G2
SPRY2 sprouty homolog 2 (Drosophila)
SPTB spectrin, beta, erythrocytic
ST20 suppressor of tumorigenicity 20
TAGLN3 transgelin 3
TBC1D2 TBC1 domain family, member 2
TBCD tubulin folding cofactor D
TBX6 T-box 6
TEX15 testis expressed 15
TGFB2 transforming growth factor, beta 2
THTPA thiamine triphosphatase
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM212 transmembrane protein 212
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TPM3 tropomyosin 3
TPSG1 tryptase gamma 1
TSC22D4 TSC22 domain family, member 4
TTC38 tetratricopeptide repeat domain 38
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGT8 UDP glycosyltransferase 8
UPK2 uroplakin 2
VIPR1 vasoactive intestinal peptide receptor 1
WDR62 WD repeat domain 62

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALS2CL ALS2 C-terminal like
BCL2L2 BCL2-like 2
BCL9 B-cell CLL/lymphoma 9
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C9ORF9 chromosome 9 open reading frame 9
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CD83 CD83 molecule
CDK20 cyclin-dependent kinase 20
CIR1 corepressor interacting with RBPJ, 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC4 excision repair cross-complementation group 4
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM114A2 family with sequence similarity 114, member A2
FBXO22 F-box protein 22
FKBP5 FK506 binding protein 5
FOXD1 forkhead box D1
FOXI1 forkhead box I1
FUZ fuzzy planar cell polarity protein
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH3 G patch domain containing 3
GSTZ1 glutathione S-transferase zeta 1
GTF2I general transcription factor IIi
HDAC11 histone deacetylase 11
HIST1H2BH histone cluster 1, H2bh
HIST1H2BI histone cluster 1, H2bi
HIST1H4F histone cluster 1, H4f
HP1BP3 heterochromatin protein 1, binding protein 3
IFT22 intraflagellar transport 22
IPO8 importin 8
IREB2 iron-responsive element binding protein 2
ISOC2 isochorismatase domain containing 2
ITPKB inositol-trisphosphate 3-kinase B
KAT2A K(lysine) acetyltransferase 2A
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
LAMB3 laminin, beta 3
LIN7A lin-7 homolog A (C. elegans)
LRRC37A2 leucine rich repeat containing 37, member A2
LYRM9 LYR motif containing 9
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCOLN3 mucolipin 3
METTL16 methyltransferase like 16
MGC12488
NPM3 nucleophosmin/nucleoplasmin 3
NRSN2 neurensin 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCDHGB5 protocadherin gamma subfamily B, 5
PEX12 peroxisomal biogenesis factor 12
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PLEKHO2 pleckstrin homology domain containing, family O member 2
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3A RAB3A, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD51B RAD51 paralog B
RAD54L RAD54-like (S. cerevisiae)
RLN2 relaxin 2
RNF39 ring finger protein 39
RPL36 ribosomal protein L36
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX12 SRY (sex determining region Y)-box 12
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOP1 thimet oligopeptidase 1
TMEM183A transmembrane protein 183A
TRIM25 tripartite motif containing 25
TRIM44 tripartite motif containing 44
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC33 tetratricopeptide repeat domain 33
UBXN6 UBX domain protein 6
ZBED8 zinc finger, BED-type containing 8
ZNF134 zinc finger protein 134
ZNF350 zinc finger protein 350
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747