griseofulvin-2332 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the griseofulvin-2332 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGPTL2 angiopoietin-like 2
AOAH acyloxyacyl hydrolase (neutrophil)
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARL4C ADP-ribosylation factor-like 4C
ATF7IP activating transcription factor 7 interacting protein
ATXN2L ataxin 2-like
BMP7 bone morphogenetic protein 7
CA12 carbonic anhydrase XII
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD177 CD177 molecule
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CFP complement factor properdin
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COQ6 coenzyme Q6 monooxygenase
DACH1 dachshund family transcription factor 1
DAPK2 death-associated protein kinase 2
DDR1 discoidin domain receptor tyrosine kinase 1
DHODH dihydroorotate dehydrogenase (quinone)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLX4 distal-less homeobox 4
DOK3 docking protein 3
EFCAB14 EF-hand calcium binding domain 14
EFR3B EFR3 homolog B (S. cerevisiae)
EMID1 EMI domain containing 1
ETV5 ets variant 5
FBXL7 F-box and leucine-rich repeat protein 7
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FOXA1 forkhead box A1
FRMD8 FERM domain containing 8
GRIK5 glutamate receptor, ionotropic, kainate 5
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA1L heat shock 70kDa protein 1-like
IL1R1 interleukin 1 receptor, type I
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIF25 kinesin family member 25
KRT31 keratin 31, type I
KRT85 keratin 85, type II
KYNU kynureninase
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC157562 uncharacterized LOC157562
MCPH1 microcephalin 1
MECOM MDS1 and EVI1 complex locus
MKL1 megakaryoblastic leukemia (translocation) 1
MRAS muscle RAS oncogene homolog
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MTSS1L metastasis suppressor 1-like
MYT1 myelin transcription factor 1
NEB nebulin
NECAB2 N-terminal EF-hand calcium binding protein 2
NF2 neurofibromin 2 (merlin)
NIPAL3 NIPA-like domain containing 3
NKTR natural killer cell triggering receptor
NMT2 N-myristoyltransferase 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPIPB3 nuclear pore complex interacting protein family, member B3
NUMA1 nuclear mitotic apparatus protein 1
OMD osteomodulin
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX1 paired box 1
PCBP4 poly(rC) binding protein 4
PCDHGB5 protocadherin gamma subfamily B, 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PENK proenkephalin
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLSCR3 phospholipid scramblase 3
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSD3 pleckstrin and Sec7 domain containing 3
PTCRA pre T-cell antigen receptor alpha
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PVR poliovirus receptor
RGS6 regulator of G-protein signaling 6
RIMBP2 RIMS binding protein 2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SCAND2P SCAN domain containing 2 pseudogene
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIRPB1 signal-regulatory protein beta 1
SLC25A44 solute carrier family 25, member 44
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SRRM2 serine/arginine repetitive matrix 2
STC2 stanniocalcin 2
SYNGR1 synaptogyrin 1
SYT11 synaptotagmin XI
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRAF3IP3 TRAF3 interacting protein 3
TREM1 triggering receptor expressed on myeloid cells 1
TRIM15 tripartite motif containing 15
VCAN versican
ZC3H7B zinc finger CCCH-type containing 7B
ZC4H2 zinc finger, C4H2 domain containing
ZNF235 zinc finger protein 235
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGO4 argonaute RISC catalytic component 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAK1 BCL2-antagonist/killer 1
BMP15 bone morphogenetic protein 15
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF71 chromosome 11 open reading frame 71
C19ORF54 chromosome 19 open reading frame 54
CAPN5 calpain 5
CBR4 carbonyl reductase 4
CBX4 chromobox homolog 4
CBY1 chibby homolog 1 (Drosophila)
CCDC85C coiled-coil domain containing 85C
CCL2 chemokine (C-C motif) ligand 2
CIR1 corepressor interacting with RBPJ, 1
CLCN6 chloride channel, voltage-sensitive 6
CLEC7A C-type lectin domain family 7, member A
COG4 component of oligomeric golgi complex 4
CPT2 carnitine palmitoyltransferase 2
CSF3R colony stimulating factor 3 receptor (granulocyte)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
EDAR ectodysplasin A receptor
EFCAB2 EF-hand calcium binding domain 2
EFHC1 EF-hand domain (C-terminal) containing 1
ELAC1 elaC ribonuclease Z 1
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM114A2 family with sequence similarity 114, member A2
FAM57A family with sequence similarity 57, member A
FAM86B1 family with sequence similarity 86, member B1
FHIT fragile histidine triad
FHL3 four and a half LIM domains 3
FKBPL FK506 binding protein like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOLM1 golgi membrane protein 1
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
HIST1H2AJ histone cluster 1, H2aj
HIST3H2A histone cluster 3, H2a
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFT81 intraflagellar transport 81
IL2RG interleukin 2 receptor, gamma
IMPACT impact RWD domain protein
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IREB2 iron-responsive element binding protein 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KAT2B K(lysine) acetyltransferase 2B
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAX1 lymphocyte transmembrane adaptor 1
LINC00339 long intergenic non-protein coding RNA 339
MAGEB2 melanoma antigen family B2
MILR1 mast cell immunoglobulin-like receptor 1
MLYCD malonyl-CoA decarboxylase
MUTYH mutY homolog
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NLK nemo-like kinase
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCYOX1L prenylcysteine oxidase 1 like
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIR pirin (iron-binding nuclear protein)
PKN1 protein kinase N1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
RIN1 Ras and Rab interactor 1
RNF167 ring finger protein 167
RPL23AP7 ribosomal protein L23a pseudogene 7
RWDD2B RWD domain containing 2B
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SETD8 SET domain containing (lysine methyltransferase) 8
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC10A3 solute carrier family 10, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SPATA2L spermatogenesis associated 2-like
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
STAG3 stromal antigen 3
SUGP1 SURP and G patch domain containing 1
SURF2 surfeit 2
SYNJ2BP synaptojanin 2 binding protein
TBX19 T-box 19
TBXAS1 thromboxane A synthase 1 (platelet)
TET3 tet methylcytosine dioxygenase 3
TEX264 testis expressed 264
TMEM134 transmembrane protein 134
TMEM5 transmembrane protein 5
TRIM66 tripartite motif containing 66
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSPAN13 tetraspanin 13
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC119 unc-119 homolog (C. elegans)
UNKL unkempt family zinc finger-like
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
ZNF701 zinc finger protein 701