growth hormone signaling pathway Gene Set

Dataset Biocarta Pathways
Category structural or functional annotations
Type pathway
Description The growth hormone signaling pathway is an important regulator of postnatal development. However, despite many years of research, the molecular mechanism underlying its many actions are incompletely understood. It is believed that its actions involve direct and indirect routes. An example of the latter is the role the pathway plays in stimulating the production of insulin-like growth factor. (Pathway Ontology, PW_0000562)
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22 proteins participating in the growth hormone signaling pathway pathway from the Biocarta Pathways dataset.

Symbol Name
CISH cytokine inducible SH2-containing protein
GH1 growth hormone 1
GHR growth hormone receptor
GRB2 growth factor receptor-bound protein 2
HNF1A HNF1 homeobox A
INS insulin
INSR insulin receptor
IRS1 insulin receptor substrate 1
JAK2 Janus kinase 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SOS1 son of sevenless homolog 1 (Drosophila)
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B