| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the guaifenesin-2569 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRA2C | adrenoceptor alpha 2C |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| ALS2CL | ALS2 C-terminal like |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BMP7 | bone morphogenetic protein 7 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C21ORF62 | chromosome 21 open reading frame 62 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CAPN9 | calpain 9 |
| CD52 | CD52 molecule |
| CDC25C | cell division cycle 25C |
| CDO1 | cysteine dioxygenase type 1 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COPE | coatomer protein complex, subunit epsilon |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CTBP2 | C-terminal binding protein 2 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDA | ectodysplasin A |
| EMID1 | EMI domain containing 1 |
| ERICH1 | glutamate-rich 1 |
| FADS3 | fatty acid desaturase 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GALNT8 | polypeptide N-acetylgalactosaminyltransferase 8 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GHRHR | growth hormone releasing hormone receptor |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HAB1 | B1 for mucin |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HFE | hemochromatosis |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HIST1H2BC | histone cluster 1, H2bc |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LAMA4 | laminin, alpha 4 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAX | MYC associated factor X |
| MBD2 | methyl-CpG binding domain protein 2 |
| MR1 | major histocompatibility complex, class I-related |
| NANOG | Nanog homeobox |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF2 | neurofibromin 2 (merlin) |
| NID1 | nidogen 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLK | nemo-like kinase |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE7B | phosphodiesterase 7B |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PLK3 | polo-like kinase 3 |
| PLXNA3 | plexin A3 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RTN2 | reticulon 2 |
| RXRA | retinoid X receptor, alpha |
| SLAMF8 | SLAM family member 8 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SSPN | sarcospan |
| STAB2 | stabilin 2 |
| STAG3 | stromal antigen 3 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| THEM6 | thioesterase superfamily member 6 |
| TIMELESS | timeless circadian clock |
| TMEM206 | transmembrane protein 206 |
| TRO | trophinin |
| TUSC3 | tumor suppressor candidate 3 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UNC13A | unc-13 homolog A (C. elegans) |
| VPS9D1 | VPS9 domain containing 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZFHX4 | zinc finger homeobox 4 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF280B | zinc finger protein 280B |
| ZNF287 | zinc finger protein 287 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACVR1 | activin A receptor, type I |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARSB | arylsulfatase B |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDC37L1 | cell division cycle 37-like 1 |
| CDHR2 | cadherin-related family member 2 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CELP | carboxyl ester lipase pseudogene |
| CHML | choroideremia-like (Rab escort protein 2) |
| CKB | creatine kinase, brain |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CSNK1G3 | casein kinase 1, gamma 3 |
| CTSO | cathepsin O |
| CXORF56 | chromosome X open reading frame 56 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DFNA5 | deafness, autosomal dominant 5 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DUSP2 | dual specificity phosphatase 2 |
| FGF6 | fibroblast growth factor 6 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GCH1 | GTP cyclohydrolase 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GPR137B | G protein-coupled receptor 137B |
| GPR68 | G protein-coupled receptor 68 |
| HAMP | hepcidin antimicrobial peptide |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BN | histone cluster 1, H2bn |
| HSPA2 | heat shock 70kDa protein 2 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1024 | KIAA1024 |
| KIAA1456 | KIAA1456 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOXL3 | lysyl oxidase-like 3 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MRAS | muscle RAS oncogene homolog |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MTSS1L | metastasis suppressor 1-like |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYH15 | myosin, heavy chain 15 |
| NOL12 | nucleolar protein 12 |
| OCEL1 | occludin/ELL domain containing 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMP22 | peripheral myelin protein 22 |
| POLL | polymerase (DNA directed), lambda |
| POM121 | POM121 transmembrane nucleoporin |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB33B | RAB33B, member RAS oncogene family |
| RNF2 | ring finger protein 2 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TESK2 | testis-specific kinase 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM159 | transmembrane protein 159 |
| TMEM212 | transmembrane protein 212 |
| TMEM53 | transmembrane protein 53 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| TXNDC15 | thioredoxin domain containing 15 |
| UCN | urocortin |
| UPB1 | ureidopropionase, beta |
| VANGL1 | VANGL planar cell polarity protein 1 |
| WDR33 | WD repeat domain 33 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF280A | zinc finger protein 280A |
| ZNF426 | zinc finger protein 426 |
| ZNF468 | zinc finger protein 468 |
| ZNF76 | zinc finger protein 76 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
