guaifenesin-3431 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the guaifenesin-3431 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFAP1 actin filament associated protein 1
ALOX15 arachidonate 15-lipoxygenase
ANXA2P3 annexin A2 pseudogene 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARHGAP44 Rho GTPase activating protein 44
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASAP1-IT1 ASAP1 intronic transcript 1
ATM ATM serine/threonine kinase
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
C11ORF63 chromosome 11 open reading frame 63
C17ORF59 chromosome 17 open reading frame 59
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD82 CD82 molecule
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CTAGE5 CTAGE family, member 5
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
EHD1 EH-domain containing 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FANCC Fanconi anemia, complementation group C
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FDPS farnesyl diphosphate synthase
FKBP8 FK506 binding protein 8, 38kDa
FOXN3 forkhead box N3
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GREB1 growth regulation by estrogen in breast cancer 1
GYG2 glycogenin 2
HIST1H2AI histone cluster 1, H2ai
HP haptoglobin
HPS1 Hermansky-Pudlak syndrome 1
ICAM1 intercellular adhesion molecule 1
ICK intestinal cell (MAK-like) kinase
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
INADL InaD-like (Drosophila)
IQCE IQ motif containing E
IQCG IQ motif containing G
KLHL22 kelch-like family member 22
KPNB1 karyopherin (importin) beta 1
LY6D lymphocyte antigen 6 complex, locus D
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
MKL1 megakaryoblastic leukemia (translocation) 1
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NGDN neuroguidin, EIF4E binding protein
NR2C1 nuclear receptor subfamily 2, group C, member 1
OLFML2A olfactomedin-like 2A
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCNXL2 pecanex-like 2 (Drosophila)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PGBD5 piggyBac transposable element derived 5
PHF20 PHD finger protein 20
PKP3 plakophilin 3
PLAGL1 pleiomorphic adenoma gene-like 1
PLCH1 phospholipase C, eta 1
PMEL premelanosome protein
POLL polymerase (DNA directed), lambda
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRF1 perforin 1 (pore forming protein)
PRKD3 protein kinase D3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS12 regulator of G-protein signaling 12
RPL18 ribosomal protein L18
RPS28 ribosomal protein S28
SCAMP4 secretory carrier membrane protein 4
SERHL2 serine hydrolase-like 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIRT3 sirtuin 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SMTN smoothelin
SP100 SP100 nuclear antigen
SPARCL1 SPARC-like 1 (hevin)
SRCAP Snf2-related CREBBP activator protein
SRPX sushi-repeat containing protein, X-linked
STOML1 stomatin (EPB72)-like 1
SYCP2 synaptonemal complex protein 2
TADA2A transcriptional adaptor 2A
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBC1D22A TBC1 domain family, member 22A
TBX10 T-box 10
TFE3 transcription factor binding to IGHM enhancer 3
TMOD1 tropomodulin 1
TNS1 tensin 1
UNC119 unc-119 homolog (C. elegans)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF117 zinc finger protein 117
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHD1 bromo adjacent homology domain containing 1
BATF basic leucine zipper transcription factor, ATF-like
BBC3 BCL2 binding component 3
BIN3 bridging integrator 3
CAMTA2 calmodulin binding transcription activator 2
CDK3 cyclin-dependent kinase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPI centromere protein I
CGREF1 cell growth regulator with EF-hand domain 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLSPN claspin
COPS7B COP9 signalosome subunit 7B
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DCAF13 DDB1 and CUL4 associated factor 13
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGKE diacylglycerol kinase, epsilon 64kDa
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
FAM114A2 family with sequence similarity 114, member A2
FAM192A family with sequence similarity 192, member A
FAM53B family with sequence similarity 53, member B
FAM63A family with sequence similarity 63, member A
FGD6 FYVE, RhoGEF and PH domain containing 6
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIRA histone cell cycle regulator
HSPA1L heat shock 70kDa protein 1-like
IFT81 intraflagellar transport 81
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
KDM5C lysine (K)-specific demethylase 5C
KDM7A lysine (K)-specific demethylase 7A
KREMEN2 kringle containing transmembrane protein 2
LYPLA2P1 lysophospholipase II pseudogene 1
LZTFL1 leucine zipper transcription factor-like 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP6D1 MAP6 domain containing 1
MDN1 MDN1, midasin homolog (yeast)
MEIS2 Meis homeobox 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGC12488
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NES nestin
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PGPEP1 pyroglutamyl-peptidase I
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLA2G3 phospholipase A2, group III
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRR14L proline rich 14-like
PTDSS2 phosphatidylserine synthase 2
QSER1 glutamine and serine rich 1
RANBP17 RAN binding protein 17
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
RNF31 ring finger protein 31
RRAGB Ras-related GTP binding B
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF160 zinc finger protein 160
ZNF562 zinc finger protein 562
ZNF606 zinc finger protein 606
ZNF611 zinc finger protein 611
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF787 zinc finger protein 787