| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the guaifenesin-4371 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ANGPT4 | angiopoietin 4 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP11A | ATPase, class VI, type 11A |
| BAX | BCL2-associated X protein |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BST2 | bone marrow stromal cell antigen 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C3 | complement component 3 |
| CALCR | calcitonin receptor |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CDH18 | cadherin 18, type 2 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLCA1 | chloride channel accessory 1 |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPHA5 | EPH receptor A5 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM49A | family with sequence similarity 49, member A |
| FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GK | glycerol kinase |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIRA | histone cell cycle regulator |
| IDS | iduronate 2-sulfatase |
| IFNA17 | interferon, alpha 17 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INTS1 | integrator complex subunit 1 |
| ITGA9 | integrin, alpha 9 |
| ITGB7 | integrin, beta 7 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLRAP1 | killer cell lectin-like receptor subfamily A pseudogene 1 |
| LMNB1 | lamin B1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MBD2 | methyl-CpG binding domain protein 2 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MIA | melanoma inhibitory activity |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MST1 | macrophage stimulating 1 |
| MUC3B | mucin 3B, cell surface associated |
| MXD4 | MAX dimerization protein 4 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PAX5 | paired box 5 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE10A | phosphodiesterase 10A |
| PGR | progesterone receptor |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POF1B | premature ovarian failure, 1B |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPL3L | ribosomal protein L3-like |
| S100A1 | S100 calcium binding protein A1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SHOX2 | short stature homeobox 2 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNX13 | sorting nexin 13 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TBX3 | T-box 3 |
| TNC | tenascin C |
| TRIM10 | tripartite motif containing 10 |
| TRIM17 | tripartite motif containing 17 |
| TRIM36 | tripartite motif containing 36 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSPAN32 | tetraspanin 32 |
| TTC39A | tetratricopeptide repeat domain 39A |
| UTS2 | urotensin 2 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF467 | zinc finger protein 467 |
| Symbol | Name |
|---|---|
| AFF4 | AF4/FMR2 family, member 4 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AMT | aminomethyltransferase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC68 | coiled-coil domain containing 68 |
| CD83 | CD83 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| CRLF1 | cytokine receptor-like factor 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAGLA | diacylglycerol lipase, alpha |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| EGR3 | early growth response 3 |
| EPHA2 | EPH receptor A2 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM155A | family with sequence similarity 155, member A |
| FAM184A | family with sequence similarity 184, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF23 | fibroblast growth factor 23 |
| FGL1 | fibrinogen-like 1 |
| FKBP5 | FK506 binding protein 5 |
| FKRP | fukutin related protein |
| FOSL1 | FOS-like antigen 1 |
| FOXN2 | forkhead box N2 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GATA4 | GATA binding protein 4 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GMPR | guanosine monophosphate reductase |
| GPR39 | G protein-coupled receptor 39 |
| GSTP1 | glutathione S-transferase pi 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXC4 | homeobox C4 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| KIAA0754 | KIAA0754 |
| KIFC3 | kinesin family member C3 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLHL25 | kelch-like family member 25 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT6B | keratin 6B, type II |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAL | mal, T-cell differentiation protein |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK10 | mitogen-activated protein kinase 10 |
| MCOLN3 | mucolipin 3 |
| MED31 | mediator complex subunit 31 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NLRX1 | NLR family member X1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDE12 | phosphodiesterase 12 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| POLM | polymerase (DNA directed), mu |
| PRF1 | perforin 1 (pore forming protein) |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB3D | RAB3D, member RAS oncogene family |
| RFPL1S | RFPL1 antisense RNA 1 |
| RFXAP | regulatory factor X-associated protein |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| S100A7 | S100 calcium binding protein A7 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNTA1 | syntrophin, alpha 1 |
| TRIM21 | tripartite motif containing 21 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEGFB | vascular endothelial growth factor B |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
| ZNF492 | zinc finger protein 492 |
| ZNF506 | zinc finger protein 506 |
| ZNF532 | zinc finger protein 532 |
| ZNF639 | zinc finger protein 639 |
| ZNF750 | zinc finger protein 750 |
