| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the guaifenesin-4549 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ADGRL4 | adhesion G protein-coupled receptor L4 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| ATXN3L | ataxin 3-like |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C20ORF195 | chromosome 20 open reading frame 195 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD33 | CD33 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK13 | cyclin-dependent kinase 13 |
| CDON | cell adhesion associated, oncogene regulated |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPO | centromere protein O |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC11A | C-type lectin domain family 11, member A |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCN | decorin |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DKKL1 | dickkopf-like 1 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FYB | FYN binding protein |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXD3 | homeobox D3 |
| IFNA14 | interferon, alpha 14 |
| IFNA17 | interferon, alpha 17 |
| IL36RN | interleukin 36 receptor antagonist |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT17 | keratin 17, type I |
| LEFTY2 | left-right determination factor 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRRC2 | leucine rich repeat containing 2 |
| LRRN3 | leucine rich repeat neuronal 3 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MEGF9 | multiple EGF-like-domains 9 |
| MUC8 | mucin 8 |
| MVB12B | multivesicular body subunit 12B |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NLGN1 | neuroligin 1 |
| NPR1 | natriuretic peptide receptor 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ONECUT2 | one cut homeobox 2 |
| OPRL1 | opiate receptor-like 1 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PAX1 | paired box 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLIT3 | slit homolog 3 (Drosophila) |
| SORBS2 | sorbin and SH3 domain containing 2 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TPM1 | tropomyosin 1 (alpha) |
| TRD | T cell receptor delta locus |
| TRIM10 | tripartite motif containing 10 |
| TTC12 | tetratricopeptide repeat domain 12 |
| VGF | VGF nerve growth factor inducible |
| VNN2 | vanin 2 |
| Symbol | Name |
|---|---|
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADCY6 | adenylate cyclase 6 |
| AFAP1 | actin filament associated protein 1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARMC6 | armadillo repeat containing 6 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BEX4 | brain expressed, X-linked 4 |
| C1RL | complement component 1, r subcomponent-like |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC68 | coiled-coil domain containing 68 |
| CDC37L1 | cell division cycle 37-like 1 |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLSPN | claspin |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COPS7B | COP9 signalosome subunit 7B |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPNE7 | copine VII |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTSF | cathepsin F |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYBRD1 | cytochrome b reductase 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| FADS2 | fatty acid desaturase 2 |
| FANCC | Fanconi anemia, complementation group C |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FMO4 | flavin containing monooxygenase 4 |
| FOXC1 | forkhead box C1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GAS8 | growth arrest-specific 8 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HIST1H3G | histone cluster 1, H3g |
| HOXA6 | homeobox A6 |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFI44L | interferon-induced protein 44-like |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KLK5 | kallikrein-related peptidase 5 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC16A | leucine rich repeat containing 16A |
| MCC | mutated in colorectal cancers |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOTCH1 | notch 1 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OLFML2A | olfactomedin-like 2A |
| OSBP2 | oxysterol binding protein 2 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PER3 | period circadian clock 3 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PORCN | porcupine homolog (Drosophila) |
| PRSS53 | protease, serine, 53 |
| PRSS8 | protease, serine, 8 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB25 | RAB25, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD51AP1 | RAD51 associated protein 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SALL2 | spalt-like transcription factor 2 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SH2D4A | SH2 domain containing 4A |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SOAT1 | sterol O-acyltransferase 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| THOC6 | THO complex 6 |
| TMSB15A | thymosin beta 15a |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TOR4A | torsin family 4, member A |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBG2 | tubulin, gamma 2 |
| USP18 | ubiquitin specific peptidase 18 |
| USP19 | ubiquitin specific peptidase 19 |
| USP6NL | USP6 N-terminal like |
| WDR19 | WD repeat domain 19 |
| YOD1 | YOD1 deubiquitinase |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF623 | zinc finger protein 623 |
| ZNF747 | zinc finger protein 747 |
