| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the guanabenz-1544 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOL6 | apolipoprotein L, 6 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| C1QB | complement component 1, q subcomponent, B chain |
| CD48 | CD48 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CEP290 | centrosomal protein 290kDa |
| COL11A1 | collagen, type XI, alpha 1 |
| CREBBP | CREB binding protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CUL4B | cullin 4B |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CXXC4 | CXXC finger protein 4 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DEAF1 | DEAF1 transcription factor |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DOCK5 | dedicator of cytokinesis 5 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EPS8L1 | EPS8-like 1 |
| ESR2 | estrogen receptor 2 (ER beta) |
| FAM212B | family with sequence similarity 212, member B |
| FAM46C | family with sequence similarity 46, member C |
| FFAR2 | free fatty acid receptor 2 |
| FOXG1 | forkhead box G1 |
| GRM2 | glutamate receptor, metabotropic 2 |
| GSDMB | gasdermin B |
| HEG1 | heart development protein with EGF-like domains 1 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HIST1H1D | histone cluster 1, H1d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL5RA | interleukin 5 receptor, alpha |
| INADL | InaD-like (Drosophila) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA1107 | KIAA1107 |
| KIFC3 | kinesin family member C3 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTA1 | metastasis associated 1 |
| NDNF | neuron-derived neurotrophic factor |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRSN2 | neurensin 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDLIM3 | PDZ and LIM domain 3 |
| PEG10 | paternally expressed 10 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLK3 | polo-like kinase 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRKD3 | protein kinase D3 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RBPMS | RNA binding protein with multiple splicing |
| RIF1 | replication timing regulatory factor 1 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SFRP4 | secreted frizzled-related protein 4 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPAG4 | sperm associated antigen 4 |
| SPAG8 | sperm associated antigen 8 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STX1A | syntaxin 1A (brain) |
| SYMPK | symplekin |
| TCF4 | transcription factor 4 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFB2 | transforming growth factor, beta 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TUBA3C | tubulin, alpha 3c |
| VCAN | versican |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF365 | zinc finger protein 365 |
| ZNF473 | zinc finger protein 473 |
| Symbol | Name |
|---|---|
| AFF4 | AF4/FMR2 family, member 4 |
| AMT | aminomethyltransferase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARSB | arylsulfatase B |
| ATG4A | autophagy related 4A, cysteine peptidase |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC121 | coiled-coil domain containing 121 |
| CD82 | CD82 molecule |
| CD83 | CD83 molecule |
| CFD | complement factor D (adipsin) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLSTN2 | calsyntenin 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CTSF | cathepsin F |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F2R | coagulation factor II (thrombin) receptor |
| FBXO31 | F-box protein 31 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GMPR | guanosine monophosphate reductase |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4D | histone cluster 1, H4d |
| ICK | intestinal cell (MAK-like) kinase |
| IFI35 | interferon-induced protein 35 |
| INCENP | inner centromere protein antigens 135/155kDa |
| JUNB | jun B proto-oncogene |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL21 | kelch-like family member 21 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MCC | mutated in colorectal cancers |
| MTRF1 | mitochondrial translational release factor 1 |
| MVP | major vault protein |
| NKX3-2 | NK3 homeobox 2 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G10 | phospholipase A2, group X |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PMCH | pro-melanin-concentrating hormone |
| POM121 | POM121 transmembrane nucleoporin |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PROCR | protein C receptor, endothelial |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| SDC3 | syndecan 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STRA6 | stimulated by retinoic acid 6 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TBX19 | T-box 19 |
| TCTA | T-cell leukemia translocation altered |
| THBS3 | thrombospondin 3 |
| TLR5 | toll-like receptor 5 |
| TMC5 | transmembrane channel-like 5 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UPP1 | uridine phosphorylase 1 |
| VEGFB | vascular endothelial growth factor B |
| VEGFC | vascular endothelial growth factor C |
| WDR62 | WD repeat domain 62 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF273 | zinc finger protein 273 |
| ZNF324 | zinc finger protein 324 |
| ZNF484 | zinc finger protein 484 |
| ZNF586 | zinc finger protein 586 |
| ZNF816 | zinc finger protein 816 |
