| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the guanabenz-1961 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACLY | ATP citrate lyase |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP19 | Rho GTPase activating protein 19 |
| BRAP | BRCA1 associated protein |
| CD58 | CD58 molecule |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEP57 | centrosomal protein 57kDa |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CYB561 | cytochrome b561 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DGUOK | deoxyguanosine kinase |
| EDN1 | endothelin 1 |
| EFNA1 | ephrin-A1 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| FNBP1 | formin binding protein 1 |
| GANAB | glucosidase, alpha; neutral AB |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GRAMD3 | GRAM domain containing 3 |
| GRK6 | G protein-coupled receptor kinase 6 |
| H2AFY2 | H2A histone family, member Y2 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIRIP3 | HIRA interacting protein 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| JAG1 | jagged 1 |
| KAT7 | K(lysine) acetyltransferase 7 |
| KIFAP3 | kinesin-associated protein 3 |
| LIG1 | ligase I, DNA, ATP-dependent |
| LITAF | lipopolysaccharide-induced TNF factor |
| LSM1 | LSM1, U6 small nuclear RNA associated |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MADD | MAP-kinase activating death domain |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MICALL1 | MICAL-like 1 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MT1HL1 | metallothionein 1H-like 1 |
| MYL9 | myosin, light chain 9, regulatory |
| N4BP1 | NEDD4 binding protein 1 |
| NAAA | N-acylethanolamine acid amidase |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOTCH2 | notch 2 |
| NUP93 | nucleoporin 93kDa |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PKP2 | plakophilin 2 |
| PKP4 | plakophilin 4 |
| PLAA | phospholipase A2-activating protein |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLK2 | polo-like kinase 2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRPF4B | pre-mRNA processing factor 4B |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RHOC | ras homolog family member C |
| RHOD | ras homolog family member D |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| RPL11 | ribosomal protein L11 |
| RPS2 | ribosomal protein S2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMHD1 | SAM domain and HD domain 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SNX1 | sorting nexin 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRBD1 | S1 RNA binding domain 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SURF2 | surfeit 2 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TBRG4 | transforming growth factor beta regulator 4 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM97 | transmembrane protein 97 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNRC6B | trinucleotide repeat containing 6B |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBL3 | ubiquitin-like 3 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WASL | Wiskott-Aldrich syndrome-like |
| WDR45 | WD repeat domain 45 |
| WWC2 | WW and C2 domain containing 2 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACVR2B | activin A receptor, type IIB |
| ALS2CL | ALS2 C-terminal like |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| BLM | Bloom syndrome, RecQ helicase-like |
| BTNL3 | butyrophilin-like 3 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CASZ1 | castor zinc finger 1 |
| CCDC47 | coiled-coil domain containing 47 |
| CCDC9 | coiled-coil domain containing 9 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP170B | centrosomal protein 170B |
| CFAP74 | cilia and flagella associated protein 74 |
| CISH | cytokine inducible SH2-containing protein |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CPOX | coproporphyrinogen oxidase |
| DCLRE1B | DNA cross-link repair 1B |
| DRD5 | dopamine receptor D5 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FANCC | Fanconi anemia, complementation group C |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FCHO1 | FCH domain only 1 |
| FEM1C | fem-1 homolog c (C. elegans) |
| GALR3 | galanin receptor 3 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H2BI | histone cluster 1, H2bi |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFT88 | intraflagellar transport 88 |
| IL24 | interleukin 24 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KIAA0753 | KIAA0753 |
| KIAA0894 | KIAA0894 protein |
| KLHL26 | kelch-like family member 26 |
| KPTN | kaptin (actin binding protein) |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAGEA3 | melanoma antigen family A3 |
| MAGEF1 | melanoma antigen family F1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MELK | maternal embryonic leucine zipper kinase |
| METTL8 | methyltransferase like 8 |
| MMP9 | matrix metallopeptidase 9 |
| MUC3A | mucin 3A, cell surface associated |
| MYNN | myoneurin |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NFS1 | NFS1 cysteine desulfurase |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB20 | RAB20, member RAS oncogene family |
| RAB36 | RAB36, member RAS oncogene family |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RNF167 | ring finger protein 167 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPP14 | ribonuclease P/MRP 14kDa subunit |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SERTAD3 | SERTA domain containing 3 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SP140L | SP140 nuclear body protein-like |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TAOK1 | TAO kinase 1 |
| TESK1 | testis-specific kinase 1 |
| TEX40 | testis expressed 40 |
| TRIM16 | tripartite motif containing 16 |
| TRIM5 | tripartite motif containing 5 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTC26 | tetratricopeptide repeat domain 26 |
| URGCP | upregulator of cell proliferation |
| USP21 | ubiquitin specific peptidase 21 |
| VASP | vasodilator-stimulated phosphoprotein |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF160 | zinc finger protein 160 |
| ZNF544 | zinc finger protein 544 |
| ZNF623 | zinc finger protein 623 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF8 | zinc finger protein 8 |
