| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the guanabenz-2045 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ADK | adenosine kinase |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANKRD12 | ankyrin repeat domain 12 |
| ARMT1 | acidic residue methyltransferase 1 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| AVPR1B | arginine vasopressin receptor 1B |
| AZI2 | 5-azacytidine induced 2 |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CCPG1 | cell cycle progression 1 |
| CD164 | CD164 molecule, sialomucin |
| CD68 | CD68 molecule |
| CDK17 | cyclin-dependent kinase 17 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CETN1 | centrin, EF-hand protein, 1 |
| CPOX | coproporphyrinogen oxidase |
| CTRC | chymotrypsin C (caldecrin) |
| CTSS | cathepsin S |
| CUL4A | cullin 4A |
| CXORF56 | chromosome X open reading frame 56 |
| CYB561 | cytochrome b561 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DTWD1 | DTW domain containing 1 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EIF4E | eukaryotic translation initiation factor 4E |
| ELMO2 | engulfment and cell motility 2 |
| FAM102A | family with sequence similarity 102, member A |
| FAM188A | family with sequence similarity 188, member A |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBB | hemoglobin, beta |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIST1H4J | histone cluster 1, H4j |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IDS | iduronate 2-sulfatase |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITM2B | integral membrane protein 2B |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LENEP | lens epithelial protein |
| LIN7C | lin-7 homolog C (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MEX3C | mex-3 RNA binding family member C |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MORC3 | MORC family CW-type zinc finger 3 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PIDD1 | p53-induced death domain protein 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PTCRA | pre T-cell antigen receptor alpha |
| QPCT | glutaminyl-peptide cyclotransferase |
| RB1 | retinoblastoma 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPL27A | ribosomal protein L27a |
| RPL7 | ribosomal protein L7 |
| RPS2 | ribosomal protein S2 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| RWDD3 | RWD domain containing 3 |
| SCAF4 | SR-related CTD-associated factor 4 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMC4 | structural maintenance of chromosomes 4 |
| SOCS5 | suppressor of cytokine signaling 5 |
| STAG2 | stromal antigen 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCF3 | transcription factor 3 |
| TES | testin LIM domain protein |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TJP2 | tight junction protein 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM5 | transmembrane protein 5 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TTC37 | tetratricopeptide repeat domain 37 |
| UGDH | UDP-glucose 6-dehydrogenase |
| WASL | Wiskott-Aldrich syndrome-like |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF280D | zinc finger protein 280D |
| ZNF426 | zinc finger protein 426 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD17B | abhydrolase domain containing 17B |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| ADM2 | adrenomedullin 2 |
| ALPK1 | alpha-kinase 1 |
| ARMC6 | armadillo repeat containing 6 |
| AXIN1 | axin 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| C19ORF24 | chromosome 19 open reading frame 24 |
| CA9 | carbonic anhydrase IX |
| CBR1 | carbonyl reductase 1 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD1A | CD1a molecule |
| CD248 | CD248 molecule, endosialin |
| CDIP1 | cell death-inducing p53 target 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| COG7 | component of oligomeric golgi complex 7 |
| CTSL | cathepsin L |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| ETV6 | ets variant 6 |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FAM50B | family with sequence similarity 50, member B |
| FGF4 | fibroblast growth factor 4 |
| FMOD | fibromodulin |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUZ | fuzzy planar cell polarity protein |
| GPR21 | G protein-coupled receptor 21 |
| GPS1 | G protein pathway suppressor 1 |
| GSTM5 | glutathione S-transferase mu 5 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HYAL2 | hyaluronoglucosaminidase 2 |
| KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
| KIFAP3 | kinesin-associated protein 3 |
| KLHL26 | kelch-like family member 26 |
| KPTN | kaptin (actin binding protein) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LUC7L | LUC7-like (S. cerevisiae) |
| MAPK3 | mitogen-activated protein kinase 3 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MICALL2 | MICAL-like 2 |
| MLYCD | malonyl-CoA decarboxylase |
| MON1B | MON1 secretory trafficking family member B |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXRA8 | matrix-remodelling associated 8 |
| NFS1 | NFS1 cysteine desulfurase |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPPA | natriuretic peptide A |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NVL | nuclear VCP-like |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| ORC3 | origin recognition complex, subunit 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PMEL | premelanosome protein |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| POR | P450 (cytochrome) oxidoreductase |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RIC8A | RIC8 guanine nucleotide exchange factor A |
| RNF123 | ring finger protein 123 |
| RNF220 | ring finger protein 220 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SRRD | SRR1 domain containing |
| STAC | SH3 and cysteine rich domain |
| STAR | steroidogenic acute regulatory protein |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TEFM | transcription elongation factor, mitochondrial |
| THEM6 | thioesterase superfamily member 6 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMEM206 | transmembrane protein 206 |
| TMEM242 | transmembrane protein 242 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR46 | WD repeat domain 46 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YY2 | YY2 transcription factor |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF767P | zinc finger family member 767, pseudogene |
