| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the guanabenz-4642 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADCY6 | adenylate cyclase 6 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APOB | apolipoprotein B |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ART1 | ADP-ribosyltransferase 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C2CD2L | C2CD2-like |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCDC71 | coiled-coil domain containing 71 |
| CD7 | CD7 molecule |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLDN8 | claudin 8 |
| COBL | cordon-bleu WH2 repeat protein |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| EDNRA | endothelin receptor type A |
| EFNA3 | ephrin-A3 |
| EFS | embryonal Fyn-associated substrate |
| EGFL7 | EGF-like-domain, multiple 7 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FAM134B | family with sequence similarity 134, member B |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FOXN2 | forkhead box N2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GLUL | glutamate-ammonia ligase |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPM6B | glycoprotein M6B |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HOXC4 | homeobox C4 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITPKA | inositol-trisphosphate 3-kinase A |
| LAMC2 | laminin, gamma 2 |
| LOC390998 | ribosomal protein L10 pseudogene |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP9 | matrix metallopeptidase 9 |
| NCOA2 | nuclear receptor coactivator 2 |
| NPAS2 | neuronal PAS domain protein 2 |
| NPTX1 | neuronal pentraxin I |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| NUP210 | nucleoporin 210kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| QKI | QKI, KH domain containing, RNA binding |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SETD1A | SET domain containing 1A |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOCS6 | suppressor of cytokine signaling 6 |
| SSBP2 | single-stranded DNA binding protein 2 |
| STON1 | stonin 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYCP2 | synaptonemal complex protein 2 |
| SYT17 | synaptotagmin XVII |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAPBP | TAP binding protein (tapasin) |
| THOP1 | thimet oligopeptidase 1 |
| TMEM140 | transmembrane protein 140 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNPO2 | transportin 2 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TRIM14 | tripartite motif containing 14 |
| URGCP | upregulator of cell proliferation |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| WDR18 | WD repeat domain 18 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF467 | zinc finger protein 467 |
| ZNF675 | zinc finger protein 675 |
| ZNF75D | zinc finger protein 75D |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ACE | angiotensin I converting enzyme |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F |
| ASTN1 | astrotactin 1 |
| BMP4 | bone morphogenetic protein 4 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCNO | cyclin O |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD72 | CD72 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK6 | cyclin-dependent kinase 6 |
| CEL | carboxyl ester lipase |
| CHI3L2 | chitinase 3-like 2 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CSF1R | colony stimulating factor 1 receptor |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DSPP | dentin sialophosphoprotein |
| EGF | epidermal growth factor |
| EN1 | engrailed homeobox 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBRS | fibrosin |
| FLCN | folliculin |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GPR68 | G protein-coupled receptor 68 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AL | histone cluster 1, H2al |
| HOXB9 | homeobox B9 |
| HRH2 | histamine receptor H2 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL12A | interleukin 12A |
| IL24 | interleukin 24 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KLHL28 | kelch-like family member 28 |
| KRT20 | keratin 20, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC100129648 | uncharacterized LOC100129648 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP3K7CL | MAP3K7 C-terminal like |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| METTL16 | methyltransferase like 16 |
| MYOZ1 | myozenin 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEUROD1 | neuronal differentiation 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OCA2 | oculocutaneous albinism II |
| OLFM4 | olfactomedin 4 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PCDH12 | protocadherin 12 |
| PLVAP | plasmalemma vesicle associated protein |
| PODXL2 | podocalyxin-like 2 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRDM14 | PR domain containing 14 |
| PRM2 | protamine 2 |
| PRSS53 | protease, serine, 53 |
| RAPSN | receptor-associated protein of the synapse |
| RGR | retinal G protein coupled receptor |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBX19 | T-box 19 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TCF15 | transcription factor 15 (basic helix-loop-helix) |
| TEP1 | telomerase-associated protein 1 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TSPAN2 | tetraspanin 2 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF816 | zinc finger protein 816 |
