| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the guanabenz-5703 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| APC2 | adenomatosis polyposis coli 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATN1 | atrophin 1 |
| ATXN2L | ataxin 2-like |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C8A | complement component 8, alpha polypeptide |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DLX4 | distal-less homeobox 4 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DOK3 | docking protein 3 |
| ECE1 | endothelin converting enzyme 1 |
| ETV5 | ets variant 5 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FHL1 | four and a half LIM domains 1 |
| FHL5 | four and a half LIM domains 5 |
| FN1 | fibronectin 1 |
| FOXI1 | forkhead box I1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GK | glycerol kinase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR22 | G protein-coupled receptor 22 |
| GSN | gelsolin |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HRASLS2 | HRAS-like suppressor 2 |
| IL1B | interleukin 1, beta |
| IL37 | interleukin 37 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| INTS3 | integrator complex subunit 3 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLK8 | kallikrein-related peptidase 8 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LMO4 | LIM domain only 4 |
| LPIN1 | lipin 1 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MALL | mal, T-cell differentiation protein-like |
| MUSK | muscle, skeletal, receptor tyrosine kinase |
| NEK9 | NIMA-related kinase 9 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PCDHA5 | protocadherin alpha 5 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDCD6 | programmed cell death 6 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PXN | paxillin |
| RAI2 | retinoic acid induced 2 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPL10 | ribosomal protein L10 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| S100A1 | S100 calcium binding protein A1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SPAG6 | sperm associated antigen 6 |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TEF | thyrotrophic embryonic factor |
| TLE2 | transducin-like enhancer of split 2 |
| TMEM144 | transmembrane protein 144 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSHR | thyroid stimulating hormone receptor |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF493 | zinc finger protein 493 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| AMH | anti-Mullerian hormone |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BMP15 | bone morphogenetic protein 15 |
| BMP4 | bone morphogenetic protein 4 |
| BST2 | bone marrow stromal cell antigen 2 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC87 | coiled-coil domain containing 87 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD83 | CD83 molecule |
| CEP170B | centrosomal protein 170B |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCA1 | chloride channel accessory 1 |
| CLIC2 | chloride intracellular channel 2 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DIXDC1 | DIX domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DRD1 | dopamine receptor D1 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FZD9 | frizzled class receptor 9 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR3 | G protein-coupled receptor 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BC | histone cluster 1, H2bc |
| HOXA4 | homeobox A4 |
| HOXD11 | homeobox D11 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFT54 | intraflagellar transport 54 |
| IL2 | interleukin 2 |
| IL24 | interleukin 24 |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| JUNB | jun B proto-oncogene |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0754 | KIAA0754 |
| KIAA1456 | KIAA1456 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL29 | kelch-like family member 29 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LTC4S | leukotriene C4 synthase |
| MAP2 | microtubule-associated protein 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMRN2 | multimerin 2 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLM | polymerase (DNA directed), mu |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RLN1 | relaxin 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STIM1 | stromal interaction molecule 1 |
| TBR1 | T-box, brain, 1 |
| TBX19 | T-box 19 |
| TDRD12 | tudor domain containing 12 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPYL2 | TSPY-like 2 |
| UBTD1 | ubiquitin domain containing 1 |
| USP19 | ubiquitin specific peptidase 19 |
| USP20 | ubiquitin specific peptidase 20 |
| VAX2 | ventral anterior homeobox 2 |
| VEGFB | vascular endothelial growth factor B |
| VIM | vimentin |
| XYLT2 | xylosyltransferase II |
| ZNF205 | zinc finger protein 205 |
| ZNF350 | zinc finger protein 350 |
| ZNF423 | zinc finger protein 423 |
| ZNF506 | zinc finger protein 506 |
| ZNF516 | zinc finger protein 516 |
