guanadrel-3698 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

194 genes differentially expressed following the guanadrel-3698 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ACVR1B activin A receptor, type IB
ADAM23 ADAM metallopeptidase domain 23
ADD2 adducin 2 (beta)
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ATP10A ATPase, class V, type 10A
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
C11ORF16 chromosome 11 open reading frame 16
C2ORF72 chromosome 2 open reading frame 72
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCNK cyclin K
CD4 CD4 molecule
CDK18 cyclin-dependent kinase 18
CDK2 cyclin-dependent kinase 2
CDRT1 CMT1A duplicated region transcript 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CELA3B chymotrypsin-like elastase family, member 3B
CFAP45 cilia and flagella associated protein 45
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CST2 cystatin SA
CYB5A cytochrome b5 type A (microsomal)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCLK1 doublecortin-like kinase 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPP4 dipeptidyl-peptidase 4
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
DTNA dystrobrevin, alpha
DTX3 deltex 3, E3 ubiquitin ligase
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAIM2 Fas apoptotic inhibitory molecule 2
FAM135A family with sequence similarity 135, member A
FCF1 FCF1 rRNA-processing protein
FCMR Fc fragment of IgM receptor
FZD1 frizzled class receptor 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
HIST3H3 histone cluster 3, H3
HN1L hematological and neurological expressed 1-like
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSF2 heat shock transcription factor 2
IL32 interleukin 32
IRX5 iroquois homeobox 5
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KIAA0319L KIAA0319-like
KIAA0485 uncharacterized LOC57235
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF6 Kruppel-like factor 6
LMX1B LIM homeobox transcription factor 1, beta
LPAR3 lysophosphatidic acid receptor 3
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBD2 methyl-CpG binding domain protein 2
MEF2D myocyte enhancer factor 2D
MON2 MON2 homolog (S. cerevisiae)
MRC2 mannose receptor, C type 2
MTCP1 mature T-cell proliferation 1
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NF1 neurofibromin 1
NLRP3 NLR family, pyrin domain containing 3
NPC1 Niemann-Pick disease, type C1
PDLIM4 PDZ and LIM domain 4
PER2 period circadian clock 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PTCH2 patched 2
PYY peptide YY
RAB5C RAB5C, member RAS oncogene family
RNGTT RNA guanylyltransferase and 5'-phosphatase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIGLEC8 sialic acid binding Ig-like lectin 8
SIX3 SIX homeobox 3
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOX10 SRY (sex determining region Y)-box 10
TBX5 T-box 5
TK2 thymidine kinase 2, mitochondrial
TM4SF1 transmembrane 4 L six family member 1
TTC12 tetratricopeptide repeat domain 12
TUBA4B tubulin, alpha 4b
ZFP64 ZFP64 zinc finger protein
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIRE autoimmune regulator
ALPK3 alpha-kinase 3
ARMCX2 armadillo repeat containing, X-linked 2
AXIN1 axin 1
BBC3 BCL2 binding component 3
C1QTNF3 C1q and tumor necrosis factor related protein 3
C9ORF9 chromosome 9 open reading frame 9
CBS cystathionine-beta-synthase
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CD3D CD3d molecule, delta (CD3-TCR complex)
CD80 CD80 molecule
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CEL carboxyl ester lipase
CNTFR ciliary neurotrophic factor receptor
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CORO2B coronin, actin binding protein, 2B
CPNE7 copine VII
CSRNP3 cysteine-serine-rich nuclear protein 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
DSCAM Down syndrome cell adhesion molecule
DSPP dentin sialophosphoprotein
EFNA3 ephrin-A3
FAM120C family with sequence similarity 120C
FGL1 fibrinogen-like 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GAREM GRB2 associated, regulator of MAPK1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK3P glycerol kinase 3 pseudogene
GLB1L galactosidase, beta 1-like
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HIST1H3I histone cluster 1, H3i
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
KCTD7 potassium channel tetramerization domain containing 7
KLHL25 kelch-like family member 25
LINS lines homolog (Drosophila)
LMCD1 LIM and cysteine-rich domains 1
LMO7 LIM domain 7
LPPR1 lipid phosphate phosphatase-related protein type 1
LZTR1 leucine-zipper-like transcription regulator 1
MAGEA5 melanoma antigen family A5
MAGEF1 melanoma antigen family F1
MAK male germ cell-associated kinase
MEFV Mediterranean fever
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP3 matrix metallopeptidase 3
MON1B MON1 secretory trafficking family member B
MRAS muscle RAS oncogene homolog
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NOL10 nucleolar protein 10
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PARPBP PARP1 binding protein
PCDH17 protocadherin 17
PCOLCE procollagen C-endopeptidase enhancer
PDZK1 PDZ domain containing 1
PGP phosphoglycolate phosphatase
PGPEP1 pyroglutamyl-peptidase I
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PQLC2 PQ loop repeat containing 2
PRB3 proline-rich protein BstNI subfamily 3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRPH peripherin
RAB36 RAB36, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL3 ret finger protein-like 3
RNF122 ring finger protein 122
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC41A3 solute carrier family 41, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMA4 glucuronidase, beta pseudogene
SMO smoothened, frizzled class receptor
SSTR5 somatostatin receptor 5
SYCE1L synaptonemal complex central element protein 1-like
TESPA1 thymocyte expressed, positive selection associated 1
TFCP2L1 transcription factor CP2-like 1
TMEM180 transmembrane protein 180
TRAF2 TNF receptor-associated factor 2
TRIM25 tripartite motif containing 25
WNT7A wingless-type MMTV integration site family, member 7A
ZFHX3 zinc finger homeobox 3
ZNF232 zinc finger protein 232
ZNF385D zinc finger protein 385D
ZNF506 zinc finger protein 506