guanadrel-4720 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the guanadrel-4720 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD7 ankyrin repeat domain 7
ANP32A-IT1 ANP32A intronic transcript 1
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASB1 ankyrin repeat and SOCS box containing 1
ATM ATM serine/threonine kinase
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
B9D1 B9 protein domain 1
BAX BCL2-associated X protein
C1QL1 complement component 1, q subcomponent-like 1
CACFD1 calcium channel flower domain containing 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CD22 CD22 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP162 centrosomal protein 162kDa
CFAP69 cilia and flagella associated protein 69
COL5A1 collagen, type V, alpha 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTBP2 C-terminal binding protein 2
CYLD cylindromatosis (turban tumor syndrome)
DOCK6 dedicator of cytokinesis 6
DPP4 dipeptidyl-peptidase 4
ENDOD1 endonuclease domain containing 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FBXL7 F-box and leucine-rich repeat protein 7
FLCN folliculin
FRMD4A FERM domain containing 4A
GAS2 growth arrest-specific 2
GID4 GID complex subunit 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPATCH4 G patch domain containing 4
GREB1 growth regulation by estrogen in breast cancer 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HFE hemochromatosis
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IFT54 intraflagellar transport 54
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGB8 integrin, beta 8
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLF2 Kruppel-like factor 2
KRT83 keratin 83, type II
LAMP1 lysosomal-associated membrane protein 1
LRRC37A3 leucine rich repeat containing 37, member A3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP2 microtubule-associated protein 2
MAP2K5 mitogen-activated protein kinase kinase 5
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NME5 NME/NM23 family member 5
NMT1 N-myristoyltransferase 1
OBSL1 obscurin-like 1
ONECUT2 one cut homeobox 2
OSBPL10 oxysterol binding protein-like 10
PADI3 peptidyl arginine deiminase, type III
PCDHA6 protocadherin alpha 6
PCDHB8 protocadherin beta 8
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAUR plasminogen activator, urokinase receptor
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM14 PR domain containing 14
PSG6 pregnancy specific beta-1-glycoprotein 6
QKI QKI, KH domain containing, RNA binding
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RHBDD3 rhomboid domain containing 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNGTT RNA guanylyltransferase and 5'-phosphatase
S100A8 S100 calcium binding protein A8
SCAND2P SCAN domain containing 2 pseudogene
SECTM1 secreted and transmembrane 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMG7 SMG7 nonsense mediated mRNA decay factor
SSTR5 somatostatin receptor 5
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STXBP5L syntaxin binding protein 5-like
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TESC tescalcin
TGFB2 transforming growth factor, beta 2
THSD4 thrombospondin, type I, domain containing 4
TMEM242 transmembrane protein 242
UCN urocortin
UHRF1BP1L UHRF1 binding protein 1-like
VEZT vezatin, adherens junctions transmembrane protein
WDTC1 WD and tetratricopeptide repeats 1
ZBTB1 zinc finger and BTB domain containing 1
ZC3H13 zinc finger CCCH-type containing 13
ZMYND8 zinc finger, MYND-type containing 8
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARC activity-regulated cytoskeleton-associated protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BPGM 2,3-bisphosphoglycerate mutase
C1ORF21 chromosome 1 open reading frame 21
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF27A chromosome 2 open reading frame 27A
C7ORF69 chromosome 7 open reading frame 69
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CCP110 centriolar coiled coil protein 110kDa
CD79B CD79b molecule, immunoglobulin-associated beta
CEL carboxyl ester lipase
CHML choroideremia-like (Rab escort protein 2)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCN2 chloride channel, voltage-sensitive 2
CLIC2 chloride intracellular channel 2
CNR2 cannabinoid receptor 2 (macrophage)
CORO7 coronin 7
CORT cortistatin
CRYGC crystallin, gamma C
CUEDC1 CUE domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP2 dual specificity phosphatase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELSPBP1 epididymal sperm binding protein 1
FAM110B family with sequence similarity 110, member B
FLJ22184
FRS2 fibroblast growth factor receptor substrate 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HOXC8 homeobox C8
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPA2 heat shock 70kDa protein 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIME1 Lck interacting transmembrane adaptor 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTC4S leukotriene C4 synthase
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MRPL41 mitochondrial ribosomal protein L41
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD1 neuronal differentiation 1
NPPB natriuretic peptide B
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSMR oncostatin M receptor
PLAT plasminogen activator, tissue
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POLM polymerase (DNA directed), mu
PRB3 proline-rich protein BstNI subfamily 3
PRF1 perforin 1 (pore forming protein)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFTN1 raftlin, lipid raft linker 1
RNF2 ring finger protein 2
RNF39 ring finger protein 39
RPAP1 RNA polymerase II associated protein 1
RUSC2 RUN and SH3 domain containing 2
S100A4 S100 calcium binding protein A4
SAA3P serum amyloid A3 pseudogene
SCGB2A2 secretoglobin, family 2A, member 2
SERGEF secretion regulating guanine nucleotide exchange factor
SHARPIN SHANK-associated RH domain interactor
SIK1 salt-inducible kinase 1
SNTA1 syntrophin, alpha 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRR2B small proline-rich protein 2B
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STEAP4 STEAP family member 4
STK16 serine/threonine kinase 16
TICAM1 toll-like receptor adaptor molecule 1
TMEM212 transmembrane protein 212
TUBB2B tubulin, beta 2B class IIb
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USB1 U6 snRNA biogenesis 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF180 zinc finger protein 180
ZNF37BP zinc finger protein 37B, pseudogene