| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the guanethidine-1554 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACOT11 | acyl-CoA thioesterase 11 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP11A | ATPase, class VI, type 11A |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CCNL2 | cyclin L2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) |
| CHD1L | chromodomain helicase DNA binding protein 1-like |
| CORO2A | coronin, actin binding protein, 2A |
| CORO7 | coronin 7 |
| CYB561 | cytochrome b561 |
| CYTH1 | cytohesin 1 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DIDO1 | death inducer-obliterator 1 |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DUSP2 | dual specificity phosphatase 2 |
| ELAC2 | elaC ribonuclease Z 2 |
| ELK1 | ELK1, member of ETS oncogene family |
| ELMO2 | engulfment and cell motility 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ENOSF1 | enolase superfamily member 1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial |
| HEG1 | heart development protein with EGF-like domains 1 |
| HOMER1 | homer scaffolding protein 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LMTK1 | lemur tail kinase 1 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MALT1 | MALT1 paracaspase |
| MAP4 | microtubule-associated protein 4 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MMP25 | matrix metallopeptidase 25 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYO1C | myosin IC |
| NADK | NAD kinase |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUCB1 | nucleobindin 1 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAB4B | RAB4B, member RAS oncogene family |
| RHOT2 | ras homolog family member T2 |
| RIN3 | Ras and Rab interactor 3 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RTFDC1 | replication termination factor 2 domain containing 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SIRT6 | sirtuin 6 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SNX19 | sorting nexin 19 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TEX40 | testis expressed 40 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM63A | transmembrane protein 63A |
| TMSB4Y | thymosin beta 4, Y-linked |
| TPI1 | triosephosphate isomerase 1 |
| TRAF3IP2 | TRAF3 interacting protein 2 |
| TRAIP | TRAF interacting protein |
| TRAPPC9 | trafficking protein particle complex 9 |
| UBE2L3 | ubiquitin-conjugating enzyme E2L 3 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UNC119B | unc-119 homolog B (C. elegans) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WDR48 | WD repeat domain 48 |
| ZGPAT | zinc finger, CCCH-type with G patch domain |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ACVR1 | activin A receptor, type I |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| AES | amino-terminal enhancer of split |
| ALPK1 | alpha-kinase 1 |
| ANXA3 | annexin A3 |
| APOBR | apolipoprotein B receptor |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATXN2 | ataxin 2 |
| BCL7B | B-cell CLL/lymphoma 7B |
| BEX1 | brain expressed, X-linked 1 |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC6 | coiled-coil domain containing 6 |
| CD302 | CD302 molecule |
| CISD1 | CDGSH iron sulfur domain 1 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COMMD10 | COMM domain containing 10 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNM1L | dynamin 1-like |
| DUSP12 | dual specificity phosphatase 12 |
| EDAR | ectodysplasin A receptor |
| ENDOG | endonuclease G |
| FAM63A | family with sequence similarity 63, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GORASP1 | golgi reassembly stacking protein 1, 65kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INPP5F | inositol polyphosphate-5-phosphatase F |
| JAK1 | Janus kinase 1 |
| KIAA0894 | KIAA0894 protein |
| KIF1BP | KIF1 binding protein |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LXN | latexin |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGC12488 | |
| MICB | MHC class I polypeptide-related sequence B |
| MITF | microphthalmia-associated transcription factor |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NCAPH | non-SMC condensin I complex, subunit H |
| OCEL1 | occludin/ELL domain containing 1 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PAQR3 | progestin and adipoQ receptor family member III |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCPEP1 | serine carboxypeptidase 1 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLN | sarcolipin |
| SP3 | Sp3 transcription factor |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
| STAR | steroidogenic acute regulatory protein |
| STEAP3 | STEAP family member 3, metalloreductase |
| STK39 | serine threonine kinase 39 |
| TAC3 | tachykinin 3 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TPCN1 | two pore segment channel 1 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| UBE3C | ubiquitin protein ligase E3C |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR5B | WD repeat domain 5B |
| WDR7 | WD repeat domain 7 |
| WDR82 | WD repeat domain 82 |
| ZNF12 | zinc finger protein 12 |
| ZNF274 | zinc finger protein 274 |
| ZNF529 | zinc finger protein 529 |
| ZNF573 | zinc finger protein 573 |
| ZNF652 | zinc finger protein 652 |
| ZNF768 | zinc finger protein 768 |
| ZW10 | zw10 kinetochore protein |
