| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the guanethidine-3171 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADCY9 | adenylate cyclase 9 |
| ANK2 | ankyrin 2, neuronal |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| ANPEP | alanyl (membrane) aminopeptidase |
| ANTXR1 | anthrax toxin receptor 1 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BGN | biglycan |
| BTG3 | BTG family, member 3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASKIN2 | CASK interacting protein 2 |
| CCDC64 | coiled-coil domain containing 64 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CLIP3 | CAP-GLY domain containing linker protein 3 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPZ | carboxypeptidase Z |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DOCK4 | dedicator of cytokinesis 4 |
| DUOX2 | dual oxidase 2 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXL2 | forkhead box L2 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GFI1 | growth factor independent 1 transcription repressor |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GPM6B | glycoprotein M6B |
| GPSM3 | G-protein signaling modulator 3 |
| GSAP | gamma-secretase activating protein |
| GSTA3 | glutathione S-transferase alpha 3 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H3I | histone cluster 1, H3i |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HLF | hepatic leukemia factor |
| HOXD9 | homeobox D9 |
| IL1RN | interleukin 1 receptor antagonist |
| IL27RA | interleukin 27 receptor, alpha |
| JAK2 | Janus kinase 2 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIMK1 | LIM domain kinase 1 |
| LMO7 | LIM domain 7 |
| LMTK1 | lemur tail kinase 1 |
| LRRC15 | leucine rich repeat containing 15 |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MINK1 | misshapen-like kinase 1 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MST1L | macrophage stimulating 1-like |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NEUROD1 | neuronal differentiation 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NRG1 | neuregulin 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NYNRIN | NYN domain and retroviral integrase containing |
| PCDH1 | protocadherin 1 |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PDLIM5 | PDZ and LIM domain 5 |
| PDPN | podoplanin |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLTP | phospholipid transfer protein |
| PLXNC1 | plexin C1 |
| PON3 | paraoxonase 3 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRSS53 | protease, serine, 53 |
| PXDC1 | PX domain containing 1 |
| RECQL5 | RecQ protein-like 5 |
| RIN3 | Ras and Rab interactor 3 |
| RUNX1 | runt-related transcription factor 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SYNJ2 | synaptojanin 2 |
| TACR1 | tachykinin receptor 1 |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TOX | thymocyte selection-associated high mobility group box |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| VENTXP1 | VENT homeobox pseudogene 1 |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADM | adrenomedullin |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC132 | coiled-coil domain containing 132 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHKB | choline kinase beta |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CST6 | cystatin E/M |
| CTC1 | CTS telomere maintenance complex component 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| FUZ | fuzzy planar cell polarity protein |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLI3 | GLI family zinc finger 3 |
| GMPR | guanosine monophosphate reductase |
| GPR87 | G protein-coupled receptor 87 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXC5 | homeobox C5 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFT140 | intraflagellar transport 140 |
| ITGA10 | integrin, alpha 10 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF13A | kinesin family member 13A |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT13 | keratin 13, type I |
| KRT83 | keratin 83, type II |
| LDHB | lactate dehydrogenase B |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRRC61 | leucine rich repeat containing 61 |
| LYZ | lysozyme |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| METTL16 | methyltransferase like 16 |
| MPO | myeloperoxidase |
| MSI1 | musashi RNA-binding protein 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NDE1 | nudE neurodevelopment protein 1 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUPL2 | nucleoporin like 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAD51B | RAD51 paralog B |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF39 | ring finger protein 39 |
| S100A4 | S100 calcium binding protein A4 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRGN | serglycin |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYCP2 | synaptonemal complex protein 2 |
| TCTA | T-cell leukemia translocation altered |
| TET3 | tet methylcytosine dioxygenase 3 |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3D | tubulin, alpha 3d |
| ULBP2 | UL16 binding protein 2 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF34 | zinc finger protein 34 |
| ZNF432 | zinc finger protein 432 |
| ZNF442 | zinc finger protein 442 |
| ZNF573 | zinc finger protein 573 |
| ZNF701 | zinc finger protein 701 |
