| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the guanethidine-5731 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| AGRP | agouti related neuropeptide |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATP9A | ATPase, class II, type 9A |
| BDKRB1 | bradykinin receptor B1 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CALHM2 | calcium homeostasis modulator 2 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CORO1A | coronin, actin binding protein, 1A |
| CPB2 | carboxypeptidase B2 (plasma) |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| DUOX2 | dual oxidase 2 |
| FGF12 | fibroblast growth factor 12 |
| FKBP15 | FK506 binding protein 15, 133kDa |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GPM6A | glycoprotein M6A |
| GPR1 | G protein-coupled receptor 1 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GYG2 | glycogenin 2 |
| HEMK1 | HemK methyltransferase family member 1 |
| HFE | hemochromatosis |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOMER3 | homer scaffolding protein 3 |
| HP | haptoglobin |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IL11 | interleukin 11 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| IZUMO4 | IZUMO family member 4 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KLHL23 | kelch-like family member 23 |
| KLHL25 | kelch-like family member 25 |
| KRT86 | keratin 86, type II |
| LDAH | lipid droplet associated hydrolase |
| LIMD2 | LIM domain containing 2 |
| LIMK2 | LIM domain kinase 2 |
| LMO7 | LIM domain 7 |
| LMX1B | LIM homeobox transcription factor 1, beta |
| MAGEA8 | melanoma antigen family A8 |
| MCOLN3 | mucolipin 3 |
| MMRN1 | multimerin 1 |
| MTMR8 | myotubularin related protein 8 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PHF14 | PHD finger protein 14 |
| POU4F1 | POU class 4 homeobox 1 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| RAB6B | RAB6B, member RAS oncogene family |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RNF185 | ring finger protein 185 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STATH | statherin |
| SULF1 | sulfatase 1 |
| SYT17 | synaptotagmin XVII |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TFEB | transcription factor EB |
| TJP3 | tight junction protein 3 |
| TLN2 | talin 2 |
| TMEM176B | transmembrane protein 176B |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| UPK3B | uroplakin 3B |
| UST | uronyl-2-sulfotransferase |
| VCL | vinculin |
| ZNF234 | zinc finger protein 234 |
| ZNF235 | zinc finger protein 235 |
| ZNF268 | zinc finger protein 268 |
| ZNF446 | zinc finger protein 446 |
| ZNF76 | zinc finger protein 76 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ACVR2B | activin A receptor, type IIB |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AEN | apoptosis enhancing nuclease |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKRD36 | ankyrin repeat domain 36 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| C1R | complement component 1, r subcomponent |
| C1RL | complement component 1, r subcomponent-like |
| CAPN15 | calpain 15 |
| CCDC88C | coiled-coil domain containing 88C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDK6 | cyclin-dependent kinase 6 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CLDN15 | claudin 15 |
| CLEC2B | C-type lectin domain family 2, member B |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COQ6 | coenzyme Q6 monooxygenase |
| CTC1 | CTS telomere maintenance complex component 1 |
| DBF4B | DBF4 zinc finger B |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DIXDC1 | DIX domain containing 1 |
| EFNA3 | ephrin-A3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCC | Fanconi anemia, complementation group C |
| FOXC1 | forkhead box C1 |
| GRAMD1C | GRAM domain containing 1C |
| GRB7 | growth factor receptor-bound protein 7 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BI | histone cluster 1, H2bi |
| HOXA1 | homeobox A1 |
| HOXC10 | homeobox C10 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL6 | interleukin 6 |
| JAM3 | junctional adhesion molecule 3 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM4D | lysine (K)-specific demethylase 4D |
| MAP6D1 | MAP6 domain containing 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTMR11 | myotubularin related protein 11 |
| MX1 | MX dynamin-like GTPase 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NDE1 | nudE neurodevelopment protein 1 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PC | pyruvate carboxylase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCD1 | phospholipase C, delta 1 |
| PRAMEF11 | PRAME family member 11 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RBL1 | retinoblastoma-like 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCAI | suppressor of cancer cell invasion |
| SCAMP5 | secretory carrier membrane protein 5 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SPEG | SPEG complex locus |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAGLN | transgelin |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFB3 | transforming growth factor, beta 3 |
| THBS3 | thrombospondin 3 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRIM25 | tripartite motif containing 25 |
| TRIM9 | tripartite motif containing 9 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UNC119 | unc-119 homolog (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| XYLT2 | xylosyltransferase II |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF350 | zinc finger protein 350 |
| ZNF442 | zinc finger protein 442 |
| ZNF480 | zinc finger protein 480 |
| ZNF574 | zinc finger protein 574 |
| ZNF671 | zinc finger protein 671 |
| ZNF747 | zinc finger protein 747 |
| ZNF75D | zinc finger protein 75D |
| ZNF862 | zinc finger protein 862 |
