| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the guanfacine-1279 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APOL2 | apolipoprotein L, 2 |
| APP | amyloid beta (A4) precursor protein |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C2CD2L | C2CD2-like |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDC14A | cell division cycle 14A |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 |
| CLSPN | claspin |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CSNK1E | casein kinase 1, epsilon |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EPHB3 | EPH receptor B3 |
| EPHB6 | EPH receptor B6 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FCAR | Fc fragment of IgA receptor |
| FECH | ferrochelatase |
| G0S2 | G0/G1 switch 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GOSR2 | golgi SNAP receptor complex member 2 |
| H2AFX | H2A histone family, member X |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIRA | histone cell cycle regulator |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BI | histone cluster 1, H2bi |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IQCK | IQ motif containing K |
| IRGQ | immunity-related GTPase family, Q |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4 | microtubule-associated protein 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MARC2 | mitochondrial amidoxime reducing component 2 |
| MED16 | mediator complex subunit 16 |
| METTL2B | methyltransferase like 2B |
| MICB | MHC class I polypeptide-related sequence B |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYO1C | myosin IC |
| MYOZ3 | myozenin 3 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NLRP3 | NLR family, pyrin domain containing 3 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NOTCH2 | notch 2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PFDN6 | prefoldin subunit 6 |
| PIR | pirin (iron-binding nuclear protein) |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PTAFR | platelet-activating factor receptor |
| RETN | resistin |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| RRP1B | ribosomal RNA processing 1B |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SETD6 | SET domain containing 6 |
| SGSM3 | small G protein signaling modulator 3 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIN3B | SIN3 transcription regulator family member B |
| SIRT5 | sirtuin 5 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SPATA2L | spermatogenesis associated 2-like |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAOK3 | TAO kinase 3 |
| TBCCD1 | TBCC domain containing 1 |
| TLE3 | transducin-like enhancer of split 3 |
| TMEM63A | transmembrane protein 63A |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRAF3 | TNF receptor-associated factor 3 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| TXNL4A | thioredoxin-like 4A |
| UPK3A | uroplakin 3A |
| URGCP | upregulator of cell proliferation |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZNF248 | zinc finger protein 248 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARMC6 | armadillo repeat containing 6 |
| ASGR2 | asialoglycoprotein receptor 2 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CHMP1A | charged multivesicular body protein 1A |
| CLEC7A | C-type lectin domain family 7, member A |
| CNN2 | calponin 2 |
| CXORF56 | chromosome X open reading frame 56 |
| CYBRD1 | cytochrome b reductase 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DVL1 | dishevelled segment polarity protein 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC5 | exocyst complex component 5 |
| FAM222B | family with sequence similarity 222, member B |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FBRS | fibrosin |
| GAMT | guanidinoacetate N-methyltransferase |
| GBAS | glioblastoma amplified sequence |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPR183 | G protein-coupled receptor 183 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HMCES | 5-hydroxymethylcytosine (hmC) binding, ES cell-specific |
| INPP5F | inositol polyphosphate-5-phosphatase F |
| KAT2A | K(lysine) acetyltransferase 2A |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0556 | KIAA0556 |
| KIF1B | kinesin family member 1B |
| KLHL12 | kelch-like family member 12 |
| KLHL21 | kelch-like family member 21 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MNT | MAX network transcriptional repressor |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NBAS | neuroblastoma amplified sequence |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB5B | RAB5B, member RAS oncogene family |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF2 | ring finger protein 2 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC10A3 | solute carrier family 10, member 3 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMYD3 | SET and MYND domain containing 3 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STX5 | syntaxin 5 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TLR4 | toll-like receptor 4 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM242 | transmembrane protein 242 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TOLLIP | toll interacting protein |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRPS1 | trichorhinophalangeal syndrome I |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VASP | vasodilator-stimulated phosphoprotein |
| VILL | villin-like |
| VNN2 | vanin 2 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XAB2 | XPA binding protein 2 |
| ZNF134 | zinc finger protein 134 |
| ZNF280D | zinc finger protein 280D |
| ZNF345 | zinc finger protein 345 |
| ZNF35 | zinc finger protein 35 |
| ZNF350 | zinc finger protein 350 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF669 | zinc finger protein 669 |
| ZNF701 | zinc finger protein 701 |
| ZNF862 | zinc finger protein 862 |
