| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the guanfacine-2634 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP10 | bone morphogenetic protein 10 |
| BMP5 | bone morphogenetic protein 5 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CA4 | carbonic anhydrase IV |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CCDC40 | coiled-coil domain containing 40 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD70 | CD70 molecule |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| COL1A1 | collagen, type I, alpha 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DOK4 | docking protein 4 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GP1BB | glycoprotein Ib (platelet), beta polypeptide |
| GPATCH3 | G patch domain containing 3 |
| HBEGF | heparin-binding EGF-like growth factor |
| HEG1 | heart development protein with EGF-like domains 1 |
| HFE | hemochromatosis |
| HIST1H1T | histone cluster 1, H1t |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICAM2 | intercellular adhesion molecule 2 |
| IFT27 | intraflagellar transport 27 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LOC100129648 | uncharacterized LOC100129648 |
| MAP1A | microtubule-associated protein 1A |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MFAP3L | microfibrillar-associated protein 3-like |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MYF5 | myogenic factor 5 |
| MYL7 | myosin, light chain 7, regulatory |
| NCALD | neurocalcin delta |
| NCS1 | neuronal calcium sensor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PAX5 | paired box 5 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITX2 | paired-like homeodomain 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCD1 | phospholipase C, delta 1 |
| PML | promyelocytic leukemia |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PQBP1 | polyglutamine binding protein 1 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PYY | peptide YY |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB36 | RAB36, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RARA | retinoic acid receptor, alpha |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RGS12 | regulator of G-protein signaling 12 |
| RIF1 | replication timing regulatory factor 1 |
| SBF1 | SET binding factor 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SH2D1A | SH2 domain containing 1A |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SNTA1 | syntrophin, alpha 1 |
| SPAG8 | sperm associated antigen 8 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| T | T, brachyury homolog (mouse) |
| THOC5 | THO complex 5 |
| TMEM53 | transmembrane protein 53 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VASH2 | vasohibin 2 |
| VEGFA | vascular endothelial growth factor A |
| WDR61 | WD repeat domain 61 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC170 | coiled-coil domain containing 170 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CEP97 | centrosomal protein 97kDa |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUL9 | cullin 9 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EVPL | envoplakin |
| FILIP1L | filamin A interacting protein 1-like |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLCE | glucuronic acid epimerase |
| GLI3 | GLI family zinc finger 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GOLM1 | golgi membrane protein 1 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H3G | histone cluster 1, H3g |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IRF1 | interferon regulatory factor 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL26 | kelch-like family member 26 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP9 | microtubule-associated protein 9 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED15 | mediator complex subunit 15 |
| METTL8 | methyltransferase like 8 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NBEAL2 | neurobeachin-like 2 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHGDH | phosphoglycerate dehydrogenase |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLL | polymerase (DNA directed), lambda |
| PRR14L | proline rich 14-like |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPRG | protein tyrosine phosphatase, receptor type, G |
| RAB23 | RAB23, member RAS oncogene family |
| RASA2 | RAS p21 protein activator 2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIRT2 | sirtuin 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STX5 | syntaxin 5 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TAGLN | transgelin |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TRIM16 | tripartite motif containing 16 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| XAB2 | XPA binding protein 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF250 | zinc finger protein 250 |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
| ZNF573 | zinc finger protein 573 |
| ZNF652 | zinc finger protein 652 |
| ZNF654 | zinc finger protein 654 |
| ZNF813 | zinc finger protein 813 |
| ZXDC | ZXD family zinc finger C |
