| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the guanfacine-4660 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APOD | apolipoprotein D |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BBS9 | Bardet-Biedl syndrome 9 |
| BMP8A | bone morphogenetic protein 8a |
| C2CD2L | C2CD2-like |
| CADM4 | cell adhesion molecule 4 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CD58 | CD58 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DCTN2 | dynactin 2 (p50) |
| DIO3 | deiodinase, iodothyronine, type III |
| DOCK6 | dedicator of cytokinesis 6 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ENG | endoglin |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ESRRG | estrogen-related receptor gamma |
| FBXO22 | F-box protein 22 |
| FETUB | fetuin B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| HCG9 | HLA complex group 9 (non-protein coding) |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFFO1 | intermediate filament family orphan 1 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL2 | interleukin 2 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KRT6B | keratin 6B, type II |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMD2 | LIM domain containing 2 |
| LIPG | lipase, endothelial |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MIIP | migration and invasion inhibitory protein |
| MRAS | muscle RAS oncogene homolog |
| MST1 | macrophage stimulating 1 |
| MUC4 | mucin 4, cell surface associated |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NAAA | N-acylethanolamine acid amidase |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NIPAL2 | NIPA-like domain containing 2 |
| NTS | neurotensin |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OGFR | opioid growth factor receptor |
| ONECUT2 | one cut homeobox 2 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PEX6 | peroxisomal biogenesis factor 6 |
| PLXNB3 | plexin B3 |
| POU1F1 | POU class 1 homeobox 1 |
| PRAMEF12 | PRAME family member 12 |
| PRPH | peripherin |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RFXAP | regulatory factor X-associated protein |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS14 | ribosomal protein S14 |
| RPS3A | ribosomal protein S3A |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SLA | Src-like-adaptor |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SNN | stannin |
| SNTG1 | syntrophin, gamma 1 |
| SPI1 | Spi-1 proto-oncogene |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX7 | syntaxin 7 |
| SULF1 | sulfatase 1 |
| TBX1 | T-box 1 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| XDH | xanthine dehydrogenase |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF214 | zinc finger protein 214 |
| ZNF34 | zinc finger protein 34 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACKR3 | atypical chemokine receptor 3 |
| AGO4 | argonaute RISC catalytic component 4 |
| ALPK1 | alpha-kinase 1 |
| APOL6 | apolipoprotein L, 6 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CA11 | carbonic anhydrase XI |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCNJ | cyclin J |
| CD101 | CD101 molecule |
| CLDN1 | claudin 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CNTLN | centlein, centrosomal protein |
| CORO1A | coronin, actin binding protein, 1A |
| CREB5 | cAMP responsive element binding protein 5 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| EAF2 | ELL associated factor 2 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM110B | family with sequence similarity 110, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FKBP5 | FK506 binding protein 5 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR1 | G protein-coupled receptor 1 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4E | histone cluster 1, H4e |
| HOXA4 | homeobox A4 |
| IL32 | interleukin 32 |
| INADL | InaD-like (Drosophila) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0753 | KIAA0753 |
| KLHL28 | kelch-like family member 28 |
| LOC157562 | uncharacterized LOC157562 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTC4S | leukotriene C4 synthase |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MEIS1 | Meis homeobox 1 |
| METTL1 | methyltransferase like 1 |
| METTL16 | methyltransferase like 16 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OCA2 | oculocutaneous albinism II |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PTK6 | protein tyrosine kinase 6 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RGS17 | regulator of G-protein signaling 17 |
| RNF2 | ring finger protein 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCG5 | secretogranin V |
| SCIN | scinderin |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SH2D2A | SH2 domain containing 2A |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPATA1 | spermatogenesis associated 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAB2 | stabilin 2 |
| STEAP4 | STEAP family member 4 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM209 | transmembrane protein 209 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSC22D4 | TSC22 domain family, member 4 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF10 | zinc finger protein 10 |
| ZNF124 | zinc finger protein 124 |
| ZNF480 | zinc finger protein 480 |
| ZNF671 | zinc finger protein 671 |
