| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the guanfacine-5256 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APOC1 | apolipoprotein C-I |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARSE | arylsulfatase E (chondrodysplasia punctata 1) |
| BAIAP3 | BAI1-associated protein 3 |
| BARX2 | BARX homeobox 2 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCL6 | B-cell CLL/lymphoma 6 |
| C1QB | complement component 1, q subcomponent, B chain |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C3AR1 | complement component 3a receptor 1 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CALML5 | calmodulin-like 5 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD52 | CD52 molecule |
| CD82 | CD82 molecule |
| CLCA2 | chloride channel accessory 2 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ERP44 | endoplasmic reticulum protein 44 |
| FAM155A | family with sequence similarity 155, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXO42 | F-box protein 42 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLRX | glutaredoxin (thioltransferase) |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNRHR | gonadotropin-releasing hormone receptor |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCY2D | guanylate cyclase 2D, membrane (retina-specific) |
| HBB | hemoglobin, beta |
| HFE | hemochromatosis |
| HOXB2 | homeobox B2 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IRS2 | insulin receptor substrate 2 |
| ITGA7 | integrin, alpha 7 |
| ITGB5 | integrin, beta 5 |
| KRT17 | keratin 17, type I |
| KRT19P2 | keratin 19 pseudogene 2 |
| LOC100294391 | uncharacterized LOC100294391 |
| LPL | lipoprotein lipase |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFAP3L | microfibrillar-associated protein 3-like |
| MSI1 | musashi RNA-binding protein 1 |
| MVB12B | multivesicular body subunit 12B |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OGFR | opioid growth factor receptor |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PAX2 | paired box 2 |
| PCDHB12 | protocadherin beta 12 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLA2G3 | phospholipase A2, group III |
| PLCD1 | phospholipase C, delta 1 |
| PLK3 | polo-like kinase 3 |
| PML | promyelocytic leukemia |
| PON3 | paraoxonase 3 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPL10 | ribosomal protein L10 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNX1 | runt-related transcription factor 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SH2D3A | SH2 domain containing 3A |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC35G2 | solute carrier family 35, member G2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| TBC1D22A | TBC1 domain family, member 22A |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP63 | tumor protein p63 |
| TRIM22 | tripartite motif containing 22 |
| UBE3A | ubiquitin protein ligase E3A |
| USP2 | ubiquitin specific peptidase 2 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ALPK1 | alpha-kinase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B9D2 | B9 protein domain 2 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC132 | coiled-coil domain containing 132 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTAGE9 | CTAGE family, member 9 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNM1 | dynamin 1 |
| FBXO31 | F-box protein 31 |
| FJX1 | four jointed box 1 (Drosophila) |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLCN | folliculin |
| FOXO3 | forkhead box O3 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GK3P | glycerol kinase 3 pseudogene |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1D | histone cluster 1, H1d |
| HMOX1 | heme oxygenase 1 |
| HOXC8 | homeobox C8 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KIAA0556 | KIAA0556 |
| KIAA1107 | KIAA1107 |
| KLHL25 | kelch-like family member 25 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| MICALL2 | MICAL-like 2 |
| MTCH1 | mitochondrial carrier 1 |
| NES | nestin |
| NEUROD4 | neuronal differentiation 4 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NOL12 | nucleolar protein 12 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NOTCH1 | notch 1 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLXNA3 | plexin A3 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS53 | protease, serine, 53 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB30 | RAB30, member RAS oncogene family |
| RAB36 | RAB36, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RCAN3 | RCAN family member 3 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| SAV1 | salvador family WW domain containing protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAND1 | SCAN domain containing 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SNAP29 | synaptosomal-associated protein, 29kDa |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STX17 | syntaxin 17 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TLR5 | toll-like receptor 5 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YY2 | YY2 transcription factor |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZFHX3 | zinc finger homeobox 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
