halcinonide-2185 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the halcinonide-2185 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADCK2 aarF domain containing kinase 2
ADORA3 adenosine A3 receptor
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AQP7 aquaporin 7
AREG amphiregulin
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BIN1 bridging integrator 1
BMP7 bone morphogenetic protein 7
CAMK1G calcium/calmodulin-dependent protein kinase IG
CCL20 chemokine (C-C motif) ligand 20
CD163 CD163 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLDN7 claudin 7
CRHR1 corticotropin releasing hormone receptor 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DSCAM Down syndrome cell adhesion molecule
DUSP1 dual specificity phosphatase 1
EMP2 epithelial membrane protein 2
F11R F11 receptor
FAM13A family with sequence similarity 13, member A
FAM65B family with sequence similarity 65, member B
FAS Fas cell surface death receptor
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FPR2 formyl peptide receptor 2
FRMPD1 FERM and PDZ domain containing 1
GLRA1 glycine receptor, alpha 1
GPR3 G protein-coupled receptor 3
GRIP2 glutamate receptor interacting protein 2
GSN gelsolin
HOXA11 homeobox A11
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL11 interleukin 11
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
ISG20 interferon stimulated exonuclease gene 20kDa
ITK IL2-inducible T-cell kinase
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHL36 kelch-like family member 36
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMTK1 lemur tail kinase 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBP myelin basic protein
MDFI MyoD family inhibitor
METTL7A methyltransferase like 7A
MNX1 motor neuron and pancreas homeobox 1
MT1HL1 metallothionein 1H-like 1
MTA2 metastasis associated 1 family, member 2
MTMR3 myotubularin related protein 3
MYH14 myosin, heavy chain 14, non-muscle
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCR2 natural cytotoxicity triggering receptor 2
NF1 neurofibromin 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRP1 neuropilin 1
OLAH oleoyl-ACP hydrolase
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PASK PAS domain containing serine/threonine kinase
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PER1 period circadian clock 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLSCR3 phospholipid scramblase 3
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PSEN2 presenilin 2
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RHOH ras homolog family member H
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL7 ribosomal protein L7
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SDC2 syndecan 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SOCS1 suppressor of cytokine signaling 1
SORBS3 sorbin and SH3 domain containing 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TBXA2R thromboxane A2 receptor
THBS1 thrombospondin 1
TMEM176A transmembrane protein 176A
TMOD1 tropomodulin 1
TPST1 tyrosylprotein sulfotransferase 1
TSC22D3 TSC22 domain family, member 3
UPP1 uridine phosphorylase 1
YBX2 Y box binding protein 2
ZBTB16 zinc finger and BTB domain containing 16
ZER1 zyg-11 related, cell cycle regulator
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM15 ADAM metallopeptidase domain 15
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOL6 apolipoprotein L, 6
ARSB arylsulfatase B
BGLAP bone gamma-carboxyglutamate (gla) protein
BTBD18 BTB (POZ) domain containing 18
C14ORF93 chromosome 14 open reading frame 93
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBR1 carbonyl reductase 1
CCDC71 coiled-coil domain containing 71
CCDC9 coiled-coil domain containing 9
CCL2 chemokine (C-C motif) ligand 2
CD37 CD37 molecule
CD52 CD52 molecule
CDA cytidine deaminase
CEP97 centrosomal protein 97kDa
CHMP6 charged multivesicular body protein 6
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CIDEC cell death-inducing DFFA-like effector c
CLGN calmegin
CNR2 cannabinoid receptor 2 (macrophage)
COL9A2 collagen, type IX, alpha 2
CTRL chymotrypsin-like
CTSG cathepsin G
DUSP8 dual specificity phosphatase 8
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM222B family with sequence similarity 222, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GJA1 gap junction protein, alpha 1, 43kDa
GLCE glucuronic acid epimerase
GPR18 G protein-coupled receptor 18
GPR85 G protein-coupled receptor 85
GRAMD1B GRAM domain containing 1B
HDAC5 histone deacetylase 5
HP haptoglobin
HPSE heparanase
IDI2-AS1 IDI2 antisense RNA 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT81 intraflagellar transport 81
IL4R interleukin 4 receptor
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAMP5 lysosomal-associated membrane protein family, member 5
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
METRN meteorin, glial cell differentiation regulator
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MMP9 matrix metallopeptidase 9
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUM1 melanoma associated antigen (mutated) 1
NFE2L3 nuclear factor, erythroid 2-like 3
NOTCH1 notch 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PARG poly (ADP-ribose) glycohydrolase
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PER3 period circadian clock 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIPOX pipecolic acid oxidase
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
POLL polymerase (DNA directed), lambda
PRR14L proline rich 14-like
PSD4 pleckstrin and Sec7 domain containing 4
QPCT glutaminyl-peptide cyclotransferase
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFPL3 ret finger protein-like 3
RPL13P5 ribosomal protein L13 pseudogene 5
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC22A14 solute carrier family 22, member 14
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC38A6 solute carrier family 38, member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STARD3 StAR-related lipid transfer (START) domain containing 3
STK25 serine/threonine kinase 25
STX11 syntaxin 11
TEC tec protein tyrosine kinase
TERT telomerase reverse transcriptase
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSSC4 tumor suppressing subtransferable candidate 4
TTC26 tetratricopeptide repeat domain 26
UBXN6 UBX domain protein 6
UNC93B1 unc-93 homolog B1 (C. elegans)
ZFYVE16 zinc finger, FYVE domain containing 16
ZMYM3 zinc finger, MYM-type 3
ZNF219 zinc finger protein 219
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF747 zinc finger protein 747