| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the halofantrine-3130 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACVR1B | activin A receptor, type IB |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AIM1L | absent in melanoma 1-like |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP9A | ATPase, class II, type 9A |
| BTBD18 | BTB (POZ) domain containing 18 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASZ1 | castor zinc finger 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC25C | cell division cycle 25C |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLEC4M | C-type lectin domain family 4, member M |
| COL9A3 | collagen, type IX, alpha 3 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTTN | cortactin |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| EFNA3 | ephrin-A3 |
| ENG | endoglin |
| EPHB4 | EPH receptor B4 |
| F12 | coagulation factor XII (Hageman factor) |
| FAM76A | family with sequence similarity 76, member A |
| FAS | Fas cell surface death receptor |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FBXO31 | F-box protein 31 |
| FN1 | fibronectin 1 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GLG1 | golgi glycoprotein 1 |
| GPR15 | G protein-coupled receptor 15 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HFE | hemochromatosis |
| HIST1H2BG | histone cluster 1, H2bg |
| HMOX1 | heme oxygenase 1 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase |
| HSPA2 | heat shock 70kDa protein 2 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| IZUMO4 | IZUMO family member 4 |
| KAT2A | K(lysine) acetyltransferase 2A |
| LRRC16A | leucine rich repeat containing 16A |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAP6D1 | MAP6 domain containing 1 |
| MB | myoglobin |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| METTL7A | methyltransferase like 7A |
| MID1 | midline 1 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| MOB3B | MOB kinase activator 3B |
| MOXD1 | monooxygenase, DBH-like 1 |
| MXD4 | MAX dimerization protein 4 |
| NOV | nephroblastoma overexpressed |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OGFR | opioid growth factor receptor |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PBRM1 | polybromo 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH17 | protocadherin 17 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| PFDN6 | prefoldin subunit 6 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLCG1 | phospholipase C, gamma 1 |
| PLXNB1 | plexin B1 |
| POU4F2 | POU class 4 homeobox 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB6B | RAB6B, member RAS oncogene family |
| RPL10L | ribosomal protein L10-like |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRR | serine racemase |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| THBS1 | thrombospondin 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM140 | transmembrane protein 140 |
| UBOX5 | U-box domain containing 5 |
| UNC119 | unc-119 homolog (C. elegans) |
| VCX2 | variable charge, X-linked 2 |
| WWC1 | WW and C2 domain containing 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF276 | zinc finger protein 276 |
| ZNF428 | zinc finger protein 428 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| Symbol | Name |
|---|---|
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BEND5 | BEN domain containing 5 |
| BEST1 | bestrophin 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CD69 | CD69 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CENPO | centromere protein O |
| CEP170B | centrosomal protein 170B |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CIC | capicua transcriptional repressor |
| CLEC3B | C-type lectin domain family 3, member B |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORT | cortistatin |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EPHA4 | EPH receptor A4 |
| EPX | eosinophil peroxidase |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF22 | fibroblast growth factor 22 |
| FLT4 | fms-related tyrosine kinase 4 |
| GAA | glucosidase, alpha; acid |
| GCH1 | GTP cyclohydrolase 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR3 | G protein-coupled receptor 3 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3G | histone cluster 1, H3g |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| ICK | intestinal cell (MAK-like) kinase |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| JAM2 | junctional adhesion molecule 2 |
| JMJD4 | jumonji domain containing 4 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KPTN | kaptin (actin binding protein) |
| LOC100131510 | uncharacterized LOC100131510 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC157562 | uncharacterized LOC157562 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MEFV | Mediterranean fever |
| MRAS | muscle RAS oncogene homolog |
| MYBPH | myosin binding protein H |
| NAG18 | NAG18 mRNA |
| NCS1 | neuronal calcium sensor 1 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NXPH4 | neurexophilin 4 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE8B | phosphodiesterase 8B |
| PLCL1 | phospholipase C-like 1 |
| POLH | polymerase (DNA directed), eta |
| PRF1 | perforin 1 (pore forming protein) |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RANBP17 | RAN binding protein 17 |
| RASAL2 | RAS protein activator like 2 |
| RCAN3 | RCAN family member 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SIK1 | salt-inducible kinase 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPATA1 | spermatogenesis associated 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST7L | suppression of tumorigenicity 7 like |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TEX15 | testis expressed 15 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIGD6 | tigger transposable element derived 6 |
| TMC5 | transmembrane channel-like 5 |
| TMEM19 | transmembrane protein 19 |
| TMEM206 | transmembrane protein 206 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBTD1 | ubiquitin domain containing 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFC | vascular endothelial growth factor C |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF234 | zinc finger protein 234 |
| ZNF44 | zinc finger protein 44 |
| ZNF574 | zinc finger protein 574 |
| ZNF862 | zinc finger protein 862 |
