| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the halofantrine-6509 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| AGBL3 | ATP/GTP binding protein-like 3 |
| AGRP | agouti related neuropeptide |
| ALLC | allantoicase |
| ALS2CL | ALS2 C-terminal like |
| AMPD3 | adenosine monophosphate deaminase 3 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| CA4 | carbonic anhydrase IV |
| CD1C | CD1c molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL13A1 | collagen, type XIII, alpha 1 |
| CRAT | carnitine O-acetyltransferase |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DESI2 | desumoylating isopeptidase 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DOK4 | docking protein 4 |
| EFNA3 | ephrin-A3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EML2 | echinoderm microtubule associated protein like 2 |
| FCAR | Fc fragment of IgA receptor |
| FGA | fibrinogen alpha chain |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GGT1 | gamma-glutamyltransferase 1 |
| GNAS | GNAS complex locus |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GTPBP1 | GTP binding protein 1 |
| HIST1H2BO | histone cluster 1, H2bo |
| HMOX1 | heme oxygenase 1 |
| HOXD9 | homeobox D9 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL11 | interleukin 11 |
| IRF4 | interferon regulatory factor 4 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAGEB2 | melanoma antigen family B2 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MST1 | macrophage stimulating 1 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NUDCD3 | NudC domain containing 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLAU | plasminogen activator, urokinase |
| PLXDC1 | plexin domain containing 1 |
| PMP2 | peripheral myelin protein 2 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PROX1 | prospero homeobox 1 |
| PTCH2 | patched 2 |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RASIP1 | Ras interacting protein 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFPL3 | ret finger protein-like 3 |
| RGS20 | regulator of G-protein signaling 20 |
| RHO | rhodopsin |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RUNX1 | runt-related transcription factor 1 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SRPK3 | SRSF protein kinase 3 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STX7 | syntaxin 7 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SV2A | synaptic vesicle glycoprotein 2A |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TNNI3 | troponin I type 3 (cardiac) |
| TONSL | tonsoku-like, DNA repair protein |
| TREX1 | three prime repair exonuclease 1 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF235 | zinc finger protein 235 |
| ZNF484 | zinc finger protein 484 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AUTS2 | autism susceptibility candidate 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN2AIP | CDKN2A interacting protein |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEL | carboxyl ester lipase |
| CHST10 | carbohydrate sulfotransferase 10 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM169A | family with sequence similarity 169, member A |
| FAM184A | family with sequence similarity 184, member A |
| FAM186A | family with sequence similarity 186, member A |
| FLT4 | fms-related tyrosine kinase 4 |
| FUZ | fuzzy planar cell polarity protein |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR87 | G protein-coupled receptor 87 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0754 | KIAA0754 |
| KLHL25 | kelch-like family member 25 |
| KLHL36 | kelch-like family member 36 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LOXL3 | lysyl oxidase-like 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NLGN1 | neuroligin 1 |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPL | periplakin |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKX | protein kinase, X-linked |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RBL1 | retinoblastoma-like 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL10L | ribosomal protein L10-like |
| SAMHD1 | SAM domain and HD domain 1 |
| SECTM1 | secreted and transmembrane 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAGLN | transgelin |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCTN2 | tectonic family member 2 |
| TFRC | transferrin receptor |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRAPPC2 | trafficking protein particle complex 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBOX5 | U-box domain containing 5 |
| VIM | vimentin |
| VLDLR | very low density lipoprotein receptor |
| YEATS4 | YEATS domain containing 4 |
| ZNF516 | zinc finger protein 516 |
| ZNF675 | zinc finger protein 675 |
| ZNF747 | zinc finger protein 747 |
