haloperidol-1185 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the haloperidol-1185 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
APP amyloid beta (A4) precursor protein
AREG amphiregulin
ATG10 autophagy related 10
BAK1 BCL2-antagonist/killer 1
BIRC3 baculoviral IAP repeat containing 3
BTG2 BTG family, member 2
C5ORF45 chromosome 5 open reading frame 45
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK3 cyclin-dependent kinase 3
CEP162 centrosomal protein 162kDa
COMMD10 COMM domain containing 10
COMT catechol-O-methyltransferase
CPT1A carnitine palmitoyltransferase 1A (liver)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAL4 dynein, axonemal, light chain 4
DTNA dystrobrevin, alpha
EIF1 eukaryotic translation initiation factor 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EXD3 exonuclease 3'-5' domain containing 3
EXOC5 exocyst complex component 5
FHL3 four and a half LIM domains 3
FOXG1 forkhead box G1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GHRHR growth hormone releasing hormone receptor
GK3P glycerol kinase 3 pseudogene
GPATCH3 G patch domain containing 3
GSK3A glycogen synthase kinase 3 alpha
HINFP histone H4 transcription factor
ICAM2 intercellular adhesion molecule 2
ICOSLG inducible T-cell co-stimulator ligand
IL18 interleukin 18
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5K inositol polyphosphate-5-phosphatase K
IQCC IQ motif containing C
KIAA0753 KIAA0753
KIAA1456 KIAA1456
LAMP1 lysosomal-associated membrane protein 1
MAP7D3 MAP7 domain containing 3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDFIC MyoD family inhibitor domain containing
MED6 mediator complex subunit 6
METTL7A methyltransferase like 7A
MFSD11 major facilitator superfamily domain containing 11
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MST1 macrophage stimulating 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDE1 nudE neurodevelopment protein 1
NEFH neurofilament, heavy polypeptide
NINJ2 ninjurin 2
NRN1 neuritin 1
NTSR1 neurotensin receptor 1 (high affinity)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCM1 pericentriolar material 1
PHTF2 putative homeodomain transcription factor 2
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PSEN1 presenilin 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PYHIN1 pyrin and HIN domain family, member 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RHOBTB3 Rho-related BTB domain containing 3
RIMS2 regulating synaptic membrane exocytosis 2
RIN1 Ras and Rab interactor 1
RND1 Rho family GTPase 1
RNF25 ring finger protein 25
RPL35A ribosomal protein L35a
S1PR4 sphingosine-1-phosphate receptor 4
SCGB2A2 secretoglobin, family 2A, member 2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH2B2 SH2B adaptor protein 2
SH3BP2 SH3-domain binding protein 2
SHPK sedoheptulokinase
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SPN sialophorin
SPTAN1 spectrin, alpha, non-erythrocytic 1
SS18 synovial sarcoma translocation, chromosome 18
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STK38L serine/threonine kinase 38 like
STS steroid sulfatase (microsomal), isozyme S
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TEX261 testis expressed 261
TMEM231 transmembrane protein 231
TNS1 tensin 1
TPP1 tripeptidyl peptidase I
TRAPPC13 trafficking protein particle complex 13
TUFT1 tuftelin 1

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AEN apoptosis enhancing nuclease
AKTIP AKT interacting protein
APOBR apolipoprotein B receptor
BTBD3 BTB (POZ) domain containing 3
C17ORF70 chromosome 17 open reading frame 70
CCDC25 coiled-coil domain containing 25
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD1D CD1d molecule
CDR2L cerebellar degeneration-related protein 2-like
CHML choroideremia-like (Rab escort protein 2)
CLSPN claspin
CTAGE9 CTAGE family, member 9
CUL9 cullin 9
DDN dendrin
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNASE1L1 deoxyribonuclease I-like 1
DTX4 deltex 4, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECM1 extracellular matrix protein 1
EFTUD1 elongation factor Tu GTP binding domain containing 1
ELP6 elongator acetyltransferase complex subunit 6
ENO2 enolase 2 (gamma, neuronal)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM184A family with sequence similarity 184, member A
FANCC Fanconi anemia, complementation group C
FBRS fibrosin
FBXL7 F-box and leucine-rich repeat protein 7
FKBPL FK506 binding protein like
FOXJ2 forkhead box J2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HHLA3 HERV-H LTR-associating 3
IL4R interleukin 4 receptor
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KCNK5 potassium channel, two pore domain subfamily K, member 5
KLF13 Kruppel-like factor 13
KLHL28 kelch-like family member 28
KPTN kaptin (actin binding protein)
LAX1 lymphocyte transmembrane adaptor 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MICALL2 MICAL-like 2
MRGBP MRG/MORF4L binding protein
MXD3 MAX dimerization protein 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NPIPB3 nuclear pore complex interacting protein family, member B3
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NSUN6 NOP2/Sun domain family, member 6
NT5E 5'-nucleotidase, ecto (CD73)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARG poly (ADP-ribose) glycohydrolase
PDGFD platelet derived growth factor D
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POMT1 protein-O-mannosyltransferase 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRKCZ protein kinase C, zeta
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF144A ring finger protein 144A
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STAG3 stromal antigen 3
STBD1 starch binding domain 1
TBCCD1 TBCC domain containing 1
TBX19 T-box 19
TGM5 transglutaminase 5
TMEM104 transmembrane protein 104
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM209 transmembrane protein 209
TMOD3 tropomodulin 3 (ubiquitous)
TRIM58 tripartite motif containing 58
TXLNG taxilin gamma
UBAP1 ubiquitin associated protein 1
USP20 ubiquitin specific peptidase 20
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WWC2 WW and C2 domain containing 2
ZBTB44 zinc finger and BTB domain containing 44
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZMAT3 zinc finger, matrin-type 3
ZNF302 zinc finger protein 302
ZNF623 zinc finger protein 623
ZNF701 zinc finger protein 701
ZSCAN5A zinc finger and SCAN domain containing 5A