haloperidol-1203 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the haloperidol-1203 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ALOX12 arachidonate 12-lipoxygenase
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
C21ORF2 chromosome 21 open reading frame 2
C3AR1 complement component 3a receptor 1
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CDC14A cell division cycle 14A
CLCN4 chloride channel, voltage-sensitive 4
CNN1 calponin 1, basic, smooth muscle
CNTLN centlein, centrosomal protein
COL18A1 collagen, type XVIII, alpha 1
CSRNP3 cysteine-serine-rich nuclear protein 3
DUSP1 dual specificity phosphatase 1
ELAC2 elaC ribonuclease Z 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPS8L1 EPS8-like 1
FBLN1 fibulin 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GSK3A glycogen synthase kinase 3 alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BJ histone cluster 1, H2bj
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA4 homeobox A4
IFNA14 interferon, alpha 14
IFT27 intraflagellar transport 27
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL37 interleukin 37
INF2 inverted formin, FH2 and WH2 domain containing
INO80B INO80 complex subunit B
IQSEC2 IQ motif and Sec7 domain 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KSR1 kinase suppressor of ras 1
KYNU kynureninase
LMO4 LIM domain only 4
LOC100129648 uncharacterized LOC100129648
LOX lysyl oxidase
LTB lymphotoxin beta (TNF superfamily, member 3)
LYRM9 LYR motif containing 9
MEGF9 multiple EGF-like-domains 9
MFAP3L microfibrillar-associated protein 3-like
MST1 macrophage stimulating 1
NAGLU N-acetylglucosaminidase, alpha
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUP214 nucleoporin 214kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX26 peroxisomal biogenesis factor 26
PIDD1 p53-induced death domain protein 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKG2 protein kinase, cGMP-dependent, type II
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REC8 REC8 meiotic recombination protein
RETN resistin
RGS10 regulator of G-protein signaling 10
RNF121 ring finger protein 121
RNF39 ring finger protein 39
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNX1 runt-related transcription factor 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAPER S-phase cyclin A-associated protein in the ER
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLMO1 slowmo homolog 1 (Drosophila)
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SRD5A3 steroid 5 alpha-reductase 3
SRSF1 serine/arginine-rich splicing factor 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TAPBP TAP binding protein (tapasin)
TMEM209 transmembrane protein 209
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC9 tetratricopeptide repeat domain 9
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBA7 ubiquitin-like modifier activating enzyme 7
UBE3A ubiquitin protein ligase E3A
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
WIPF1 WAS/WASL interacting protein family, member 1
WNK1 WNK lysine deficient protein kinase 1
ZBTB6 zinc finger and BTB domain containing 6
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX2 zinc finger homeobox 2
ZNF224 zinc finger protein 224
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AHDC1 AT hook, DNA binding motif, containing 1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD40 ankyrin repeat domain 40
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARSJ arylsulfatase family, member J
BCHE butyrylcholinesterase
BOLA1 bolA family member 1
C16ORF59 chromosome 16 open reading frame 59
C2ORF44 chromosome 2 open reading frame 44
CADPS2 Ca++-dependent secretion activator 2
CDK3 cyclin-dependent kinase 3
CGREF1 cell growth regulator with EF-hand domain 1
CLIP2 CAP-GLY domain containing linker protein 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CTSO cathepsin O
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDC4 enhancer of mRNA decapping 4
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FZD3 frizzled class receptor 3
GALK1 galactokinase 1
GALT galactose-1-phosphate uridylyltransferase
GBX2 gastrulation brain homeobox 2
GLCE glucuronic acid epimerase
GNL1 guanine nucleotide binding protein-like 1
GPR19 G protein-coupled receptor 19
HIST1H2AM histone cluster 1, H2am
HOXC13 homeobox C13
IFT46 intraflagellar transport 46
IRF1 interferon regulatory factor 1
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
LPAR3 lysophosphatidic acid receptor 3
LYPD1 LY6/PLAUR domain containing 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEH1 melanoma antigen family H1
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MED15 mediator complex subunit 15
MFSD6 major facilitator superfamily domain containing 6
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPP1 membrane protein, palmitoylated 1, 55kDa
MRPL44 mitochondrial ribosomal protein L44
NCS1 neuronal calcium sensor 1
NDRG4 NDRG family member 4
NID2 nidogen 2 (osteonidogen)
NINJ1 ninjurin 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PC pyruvate carboxylase
PCF11 PCF11 cleavage and polyadenylation factor subunit
PFAS phosphoribosylformylglycinamidine synthase
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT1 protein-O-mannosyltransferase 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRKX protein kinase, X-linked
RBBP5 retinoblastoma binding protein 5
RUNX1-IT1 RUNX1 intronic transcript 1
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNPH syntaphilin
SNX24 sorting nexin 24
SPEG SPEG complex locus
SREBF1 sterol regulatory element binding transcription factor 1
STRN striatin, calmodulin binding protein
STX1A syntaxin 1A (brain)
TAGLN transgelin
TENM4 teneurin transmembrane protein 4
TEX40 testis expressed 40
TMEM120B transmembrane protein 120B
TMSB15A thymosin beta 15a
TNNI3 troponin I type 3 (cardiac)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIM9 tripartite motif containing 9
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTLL12 tubulin tyrosine ligase-like family member 12
WASF1 WAS protein family, member 1
ZHX2 zinc fingers and homeoboxes 2
ZNF286A zinc finger protein 286A
ZNF304 zinc finger protein 304
ZNF468 zinc finger protein 468
ZNF623 zinc finger protein 623
ZNF84 zinc finger protein 84