haloperidol-1539 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the haloperidol-1539 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACACB acetyl-CoA carboxylase beta
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAP2 ArfGAP with dual PH domains 2
ANXA2P3 annexin A2 pseudogene 3
APAF1 apoptotic peptidase activating factor 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASIC1 acid sensing (proton gated) ion channel 1
ATP10A ATPase, class V, type 10A
BBS9 Bardet-Biedl syndrome 9
BHLHE41 basic helix-loop-helix family, member e41
BMP4 bone morphogenetic protein 4
C19ORF66 chromosome 19 open reading frame 66
C1QL1 complement component 1, q subcomponent-like 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC57 coiled-coil domain containing 57
CD34 CD34 molecule
CDK18 cyclin-dependent kinase 18
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP290 centrosomal protein 290kDa
CEP41 centrosomal protein 41kDa
CLEC11A C-type lectin domain family 11, member A
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSF1R colony stimulating factor 1 receptor
DEFA4 defensin, alpha 4, corticostatin
DFNB31 deafness, autosomal recessive 31
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK5 dedicator of cytokinesis 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FADS2 fatty acid desaturase 2
FBXL7 F-box and leucine-rich repeat protein 7
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GYG2 glycogenin 2
HIST1H1D histone cluster 1, H1d
HOXC8 homeobox C8
HPCAL4 hippocalcin like 4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
INSIG1 insulin induced gene 1
IPO5 importin 5
IQCC IQ motif containing C
IRF4 interferon regulatory factor 4
ISG20 interferon stimulated exonuclease gene 20kDa
KRT24 keratin 24, type I
LARP4B La ribonucleoprotein domain family, member 4B
LDB3 LIM domain binding 3
LIMK1 LIM domain kinase 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMAN1 lectin, mannose-binding, 1
LOC644450 uncharacterized LOC644450
LPXN leupaxin
MAGOH2P mago-nashi homolog 2, pseudogene
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MC5R melanocortin 5 receptor
MLXIP MLX interacting protein
MMP3 matrix metallopeptidase 3
MTA1 metastasis associated 1
MYOF myoferlin
ONECUT1 one cut homeobox 1
ORAI2 ORAI calcium release-activated calcium modulator 2
OVGP1 oviductal glycoprotein 1, 120kDa
PCNXL2 pecanex-like 2 (Drosophila)
PML promyelocytic leukemia
PRR4 proline rich 4 (lacrimal)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REEP2 receptor accessory protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS3 regulator of G-protein signaling 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
SARM1 sterile alpha and TIR motif containing 1
SCG2 secretogranin II
SERHL2 serine hydrolase-like 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMIM14 small integral membrane protein 14
SP110 SP110 nuclear body protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRRT serrate, RNA effector molecule
STMN3 stathmin-like 3
SV2C synaptic vesicle glycoprotein 2C
TBC1D2 TBC1 domain family, member 2
TFPI2 tissue factor pathway inhibitor 2
TJAP1 tight junction associated protein 1 (peripheral)
TLE4 transducin-like enhancer of split 4
TROVE2 TROVE domain family, member 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
WDR55 WD repeat domain 55
WIZ widely interspaced zinc finger motifs
WSB1 WD repeat and SOCS box containing 1
ZFHX2 zinc finger homeobox 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF573 zinc finger protein 573
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARMC4 armadillo repeat containing 4
AXIN1 axin 1
BAGE B melanoma antigen
C14ORF132 chromosome 14 open reading frame 132
C14ORF93 chromosome 14 open reading frame 93
C22ORF29 chromosome 22 open reading frame 29
C5AR2 complement component 5a receptor 2
C8ORF60 chromosome 8 open reading frame 60
CBX8 chromobox homolog 8
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CLSTN2 calsyntenin 2
COL4A5 collagen, type IV, alpha 5
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTC1 CTS telomere maintenance complex component 1
CTSF cathepsin F
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND4A DENN/MADD domain containing 4A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHA2 EPH receptor A2
F2R coagulation factor II (thrombin) receptor
FAM222B family with sequence similarity 222, member B
FBXO5 F-box protein 5
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD1 FYVE, RhoGEF and PH domain containing 1
FLT4 fms-related tyrosine kinase 4
FOCAD focadhesin
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUZ fuzzy planar cell polarity protein
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCHFR GTP cyclohydrolase I feedback regulator
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMEB1 glucocorticoid modulatory element binding protein 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AJ histone cluster 1, H2aj
HOXC10 homeobox C10
JMJD4 jumonji domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LIN7A lin-7 homolog A (C. elegans)
LINS lines homolog (Drosophila)
LYRM9 LYR motif containing 9
MBTD1 mbt domain containing 1
MED22 mediator complex subunit 22
MTERF1 mitochondrial transcription termination factor 1
MUC3A mucin 3A, cell surface associated
MYBBP1A MYB binding protein (P160) 1a
MYL5 myosin, light chain 5, regulatory
MYO1E myosin IE
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NHLRC2 NHL repeat containing 2
NOL6 nucleolar protein 6 (RNA-associated)
NRGN neurogranin (protein kinase C substrate, RC3)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
RANGRF RAN guanine nucleotide release factor
RARS arginyl-tRNA synthetase
RHBDD3 rhomboid domain containing 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF39 ring finger protein 39
ROM1 retinal outer segment membrane protein 1
RPAP2 RNA polymerase II associated protein 2
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SOX3 SRY (sex determining region Y)-box 3
STAG3 stromal antigen 3
STRA6 stimulated by retinoic acid 6
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TFF2 trefoil factor 2
THBS3 thrombospondin 3
TM7SF3 transmembrane 7 superfamily member 3
TMEM104 transmembrane protein 104
TMEM121 transmembrane protein 121
TMEM184C transmembrane protein 184C
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
USP20 ubiquitin specific peptidase 20
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF35 zinc finger protein 35
ZNF787 zinc finger protein 787
ZXDC ZXD family zinc finger C