haloperidol-418 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the haloperidol-418 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACTC1 actin, alpha, cardiac muscle 1
ARPIN actin-related protein 2/3 complex inhibitor
ATXN2 ataxin 2
ATXN2L ataxin 2-like
BHLHE40 basic helix-loop-helix family, member e40
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTD biotinidase
C20ORF27 chromosome 20 open reading frame 27
C8B complement component 8, beta polypeptide
CANX calnexin
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC71 coiled-coil domain containing 71
CD79A CD79a molecule, immunoglobulin-associated alpha
CD93 CD93 molecule
CDH18 cadherin 18, type 2
CEP41 centrosomal protein 41kDa
CLCN7 chloride channel, voltage-sensitive 7
CLEC10A C-type lectin domain family 10, member A
CLTA clathrin, light chain A
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNTD2 cyclin N-terminal domain containing 2
COL11A2 collagen, type XI, alpha 2
COLEC12 collectin sub-family member 12
CRNN cornulin
CRTAC1 cartilage acidic protein 1
CRYAA crystallin, alpha A
CSF1R colony stimulating factor 1 receptor
CYP2A7P1 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1
DENND3 DENN/MADD domain containing 3
DGCR2 DiGeorge syndrome critical region gene 2
DLK2 delta-like 2 homolog (Drosophila)
DNAH3 dynein, axonemal, heavy chain 3
DRP2 dystrophin related protein 2
DUS2 dihydrouridine synthase 2
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EFNB3 ephrin-B3
ELMO2 engulfment and cell motility 2
ENGASE endo-beta-N-acetylglucosaminidase
EPOR erythropoietin receptor
FAM107A family with sequence similarity 107, member A
FAM153A family with sequence similarity 153, member A
FEM1B fem-1 homolog b (C. elegans)
FGA fibrinogen alpha chain
FLJ11292
FMO6P flavin containing monooxygenase 6 pseudogene
FN1 fibronectin 1
FNDC3A fibronectin type III domain containing 3A
FRMD1 FERM domain containing 1
GINS3 GINS complex subunit 3 (Psf3 homolog)
GOSR1 golgi SNAP receptor complex member 1
GPR4 G protein-coupled receptor 4
HEG1 heart development protein with EGF-like domains 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFT38 intraflagellar transport 38
INE1 inactivation escape 1 (non-protein coding)
KIAA0509 uncharacterized LOC57242
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMA3 laminin, alpha 3
LENEP lens epithelial protein
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
NARFL nuclear prelamin A recognition factor-like
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NMT1 N-myristoyltransferase 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCP4 Purkinje cell protein 4
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PEG3 paternally expressed 3
PGS1 phosphatidylglycerophosphate synthase 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PHEX phosphate regulating endopeptidase homolog, X-linked
PHOX2A paired-like homeobox 2a
PLCL2 phospholipase C-like 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POU5F1B POU class 5 homeobox 1B
PQLC3 PQ loop repeat containing 3
PRB1 proline-rich protein BstNI subfamily 1
PTPRA protein tyrosine phosphatase, receptor type, A
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB8B RAB8B, member RAS oncogene family
RRAS related RAS viral (r-ras) oncogene homolog
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SURF2 surfeit 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNS1 tensin 1
TRIM14 tripartite motif containing 14
TSHZ2 teashirt zinc finger homeobox 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VRK3 vaccinia related kinase 3
WNT7A wingless-type MMTV integration site family, member 7A
ZBED2 zinc finger, BED-type containing 2
ZGPAT zinc finger, CCCH-type with G patch domain

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADAMTSL4 ADAMTS-like 4
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARSA arylsulfatase A
AXIN1 axin 1
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BICD1 bicaudal D homolog 1 (Drosophila)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C20ORF195 chromosome 20 open reading frame 195
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC53 coiled-coil domain containing 53
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHPT1 choline phosphotransferase 1
CKAP2 cytoskeleton associated protein 2
CLEC1A C-type lectin domain family 1, member A
COBL cordon-bleu WH2 repeat protein
COMMD8 COMM domain containing 8
CORO1A coronin, actin binding protein, 1A
CRABP1 cellular retinoic acid binding protein 1
CRBN cereblon
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CRY1 cryptochrome circadian clock 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DCP1A decapping mRNA 1A
DCPS decapping enzyme, scavenger
DGKD diacylglycerol kinase, delta 130kDa
DMXL1 Dmx-like 1
DNAAF2 dynein, axonemal, assembly factor 2
DYSF dysferlin
EFNA1 ephrin-A1
EHD3 EH-domain containing 3
EPM2AIP1 EPM2A (laforin) interacting protein 1
EPN3 epsin 3
FANCF Fanconi anemia, complementation group F
FBXO5 F-box protein 5
FCHSD2 FCH and double SH3 domains 2
FGF16 fibroblast growth factor 16
FOXD1 forkhead box D1
FZD2 frizzled class receptor 2
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GDF3 growth differentiation factor 3
GPN3 GPN-loop GTPase 3
HINFP histone H4 transcription factor
IL36G interleukin 36, gamma
KIAA0513 KIAA0513
KIF20B kinesin family member 20B
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LINC00216 long intergenic non-protein coding RNA 216
LOC100286895 cell division cycle 27 homolog pseudogene
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MANSC1 MANSC domain containing 1
MEGF6 multiple EGF-like-domains 6
MNAT1 MNAT CDK-activating kinase assembly factor 1
MST1R macrophage stimulating 1 receptor
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO15A myosin XVA
NABP2 nucleic acid binding protein 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NRSN2 neurensin 2
OGFRL1 opioid growth factor receptor-like 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PP14571 uncharacterized LOC100130449
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
REEP4 receptor accessory protein 4
RIPPLY3 ripply transcriptional repressor 3
RNF141 ring finger protein 141
RPUSD2 RNA pseudouridylate synthase domain containing 2
SLC35E3 solute carrier family 35, member E3
SLTM SAFB-like, transcription modulator
SMO smoothened, frizzled class receptor
SMYD5 SMYD family member 5
SUSD4 sushi domain containing 4
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
THBS3 thrombospondin 3
TJP2 tight junction protein 2
TPSG1 tryptase gamma 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
WDR18 WD repeat domain 18
WT1-AS WT1 antisense RNA
ZC2HC1A zinc finger, C2HC-type containing 1A
ZCCHC6 zinc finger, CCHC domain containing 6
ZDHHC13 zinc finger, DHHC-type containing 13
ZFP36 ZFP36 ring finger protein
ZNF140 zinc finger protein 140
ZNF189 zinc finger protein 189
ZNF195 zinc finger protein 195
ZNF276 zinc finger protein 276
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701
ZNHIT6 zinc finger, HIT-type containing 6
ZSCAN9 zinc finger and SCAN domain containing 9