haloperidol-4678 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the haloperidol-4678 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADRB3 adrenoceptor beta 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATF6B activating transcription factor 6 beta
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
C17ORF59 chromosome 17 open reading frame 59
C4BPA complement component 4 binding protein, alpha
CACYBP calcyclin binding protein
CARD10 caspase recruitment domain family, member 10
CD82 CD82 molecule
CDH8 cadherin 8, type 2
CDRT1 CMT1A duplicated region transcript 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL1A1 collagen, type I, alpha 1
DGKA diacylglycerol kinase, alpha 80kDa
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
EMID1 EMI domain containing 1
FDPS farnesyl diphosphate synthase
FGFR1 fibroblast growth factor receptor 1
FGL1 fibrinogen-like 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLP1R glucagon-like peptide 1 receptor
GPM6A glycoprotein M6A
GPR37L1 G protein-coupled receptor 37 like 1
GTPBP1 GTP binding protein 1
GZMK granzyme K (granzyme 3; tryptase II)
HAMP hepcidin antimicrobial peptide
HEATR6 HEAT repeat containing 6
HPSE2 heparanase 2 (inactive)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ING1 inhibitor of growth family, member 1
IZUMO4 IZUMO family member 4
KIF1A kinesin family member 1A
KLF6 Kruppel-like factor 6
KLHL22 kelch-like family member 22
LDLR low density lipoprotein receptor
LIPG lipase, endothelial
LMNA lamin A/C
MRC2 mannose receptor, C type 2
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYL10 myosin, light chain 10, regulatory
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP54 nucleoporin 54kDa
NUPR1 nuclear protein, transcriptional regulator, 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARP8 poly (ADP-ribose) polymerase family, member 8
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX2 paired box 2
PCDHGB5 protocadherin gamma subfamily B, 5
PDCD2 programmed cell death 2
PDE10A phosphodiesterase 10A
PGLYRP4 peptidoglycan recognition protein 4
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMFBP1 polyamine modulated factor 1 binding protein 1
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PQBP1 polyglutamine binding protein 1
PRDM2 PR domain containing 2, with ZNF domain
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PROX1 prospero homeobox 1
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTBP3 polypyrimidine tract binding protein 3
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
RPS3A ribosomal protein S3A
SAA3P serum amyloid A3 pseudogene
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SIGLEC8 sialic acid binding Ig-like lectin 8
SLA Src-like-adaptor
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTB spectrin, beta, erythrocytic
SPTBN5 spectrin, beta, non-erythrocytic 5
SRSF5 serine/arginine-rich splicing factor 5
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STX7 syntaxin 7
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
THPO thrombopoietin
TIMELESS timeless circadian clock
TLN2 talin 2
TRIM2 tripartite motif containing 2
TRIM31 tripartite motif containing 31
TTLL3 tubulin tyrosine ligase-like family member 3
TXK TXK tyrosine kinase
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX3 zinc fingers and homeoboxes 3
ZNF223 zinc finger protein 223
ZNF334 zinc finger protein 334
ZNF407 zinc finger protein 407
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AFAP1 actin filament associated protein 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANXA2P3 annexin A2 pseudogene 3
ARL14 ADP-ribosylation factor-like 14
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCL2A1 BCL2-related protein A1
BDKRB1 bradykinin receptor B1
BEX1 brain expressed, X-linked 1
C17ORF70 chromosome 17 open reading frame 70
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CDH7 cadherin 7, type 2
CFD complement factor D (adipsin)
CHML choroideremia-like (Rab escort protein 2)
CISH cytokine inducible SH2-containing protein
CLCN6 chloride channel, voltage-sensitive 6
CLIC3 chloride intracellular channel 3
CLSPN claspin
CNR2 cannabinoid receptor 2 (macrophage)
CRYBA2 crystallin, beta A2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYGC crystallin, gamma C
DBR1 debranching RNA lariats 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
EDN1 endothelin 1
EGLN3 egl-9 family hypoxia-inducible factor 3
FAM110B family with sequence similarity 110, member B
FAM186A family with sequence similarity 186, member A
FAM222B family with sequence similarity 222, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
FMO4 flavin containing monooxygenase 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPC3 glypican 3
GPR1 G protein-coupled receptor 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1D histone cluster 1, H1d
HIST1H3I histone cluster 1, H3i
HOXA6 homeobox A6
HOXA7 homeobox A7
HSPA1L heat shock 70kDa protein 1-like
INADL InaD-like (Drosophila)
KIAA1107 KIAA1107
KLHL3 kelch-like family member 3
KRT20 keratin 20, type I
LMTK1 lemur tail kinase 1
LRP3 low density lipoprotein receptor-related protein 3
MCMBP minichromosome maintenance complex binding protein
MED31 mediator complex subunit 31
METTL16 methyltransferase like 16
METTL8 methyltransferase like 8
MRPL44 mitochondrial ribosomal protein L44
MTERF4 mitochondrial transcription termination factor 4
MUC3A mucin 3A, cell surface associated
MYOZ3 myozenin 3
NKX3-2 NK3 homeobox 2
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRB3 proline-rich protein BstNI subfamily 3
PTK6 protein tyrosine kinase 6
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGCC regulator of cell cycle
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPH3AL rabphilin 3A-like (without C2 domains)
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCEL sciellin
SCG2 secretogranin II
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SETMAR SET domain and mariner transposase fusion gene
SKI SKI proto-oncogene
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOBP sine oculis binding protein homolog (Drosophila)
SPINK1 serine peptidase inhibitor, Kazal type 1
SYNGR3 synaptogyrin 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN2 tectonic family member 2
TGFBI transforming growth factor, beta-induced, 68kDa
URM1 ubiquitin related modifier 1
WDR25 WD repeat domain 25
ZBTB33 zinc finger and BTB domain containing 33
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF141 zinc finger protein 141
ZNF480 zinc finger protein 480
ZNF813 zinc finger protein 813
ZNF816 zinc finger protein 816