haloperidol-5241 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the haloperidol-5241 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADAM22 ADAM metallopeptidase domain 22
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ARTN artemin
ASPH aspartate beta-hydroxylase
ATF7IP activating transcription factor 7 interacting protein
B9D2 B9 protein domain 2
BAX BCL2-associated X protein
BHLHE40 basic helix-loop-helix family, member e40
BMP5 bone morphogenetic protein 5
BMP8B bone morphogenetic protein 8b
BST2 bone marrow stromal cell antigen 2
CCL11 chemokine (C-C motif) ligand 11
CCL27 chemokine (C-C motif) ligand 27
CDK2 cyclin-dependent kinase 2
CDON cell adhesion associated, oncogene regulated
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC11A C-type lectin domain family 11, member A
COMT catechol-O-methyltransferase
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTBP2 C-terminal binding protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DESI2 desumoylating isopeptidase 2
DGCR2 DiGeorge syndrome critical region gene 2
DICER1 dicer 1, ribonuclease type III
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSC3 desmocollin 3
DST dystonin
FAM120C family with sequence similarity 120C
FBLN1 fibulin 1
FRMD4B FERM domain containing 4B
GK3P glycerol kinase 3 pseudogene
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GM2A GM2 ganglioside activator
GPER1 G protein-coupled estrogen receptor 1
HCFC1 host cell factor C1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
INADL InaD-like (Drosophila)
IRF4 interferon regulatory factor 4
ISG20 interferon stimulated exonuclease gene 20kDa
KITLG KIT ligand
KLF13 Kruppel-like factor 13
LAMP1 lysosomal-associated membrane protein 1
MEF2D myocyte enhancer factor 2D
MET MET proto-oncogene, receptor tyrosine kinase
MSMB microseminoprotein, beta-
MVD mevalonate (diphospho) decarboxylase
NEU3 sialidase 3 (membrane sialidase)
NGDN neuroguidin, EIF4E binding protein
NMT1 N-myristoyltransferase 1
NOL10 nucleolar protein 10
OMG oligodendrocyte myelin glycoprotein
PARD6B par-6 family cell polarity regulator beta
PAWR PRKC, apoptosis, WT1, regulator
PCNX pecanex homolog (Drosophila)
PLA2G10 phospholipase A2, group X
PRKCI protein kinase C, iota
PTRF polymerase I and transcript release factor
PXN paxillin
RAB6A RAB6A, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RARA retinoic acid receptor, alpha
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
S100A8 S100 calcium binding protein A8
SAFB scaffold attachment factor B
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3BP2 SH3-domain binding protein 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A4 solute carrier family 16, member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SOCS6 suppressor of cytokine signaling 6
SORT1 sortilin 1
SRPK2 SRSF protein kinase 2
STK3 serine/threonine kinase 3
SUGP1 SURP and G patch domain containing 1
SYN2 synapsin II
TCP11L1 t-complex 11, testis-specific-like 1
TLK1 tousled-like kinase 1
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM29 tripartite motif containing 29
TUBA4B tubulin, alpha 4b
WWOX WW domain containing oxidoreductase
ZBTB7A zinc finger and BTB domain containing 7A
ZCCHC4 zinc finger, CCHC domain containing 4
ZNF442 zinc finger protein 442
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AGBL5 ATP/GTP binding protein-like 5
ALS2CL ALS2 C-terminal like
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AUTS2 autism susceptibility candidate 2
BLNK B-cell linker
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C1ORF105 chromosome 1 open reading frame 105
C22ORF29 chromosome 22 open reading frame 29
C8ORF60 chromosome 8 open reading frame 60
CA11 carbonic anhydrase XI
CCDC68 coiled-coil domain containing 68
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CHPF chondroitin polymerizing factor
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPTP ceramide-1-phosphate transfer protein
CRLF1 cytokine receptor-like factor 1
CUZD1 CUB and zona pellucida-like domains 1
CXADR coxsackie virus and adenovirus receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DENND1A DENN/MADD domain containing 1A
DET1 de-etiolated homolog 1 (Arabidopsis)
DVL1 dishevelled segment polarity protein 1
DYSF dysferlin
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
FAM204A family with sequence similarity 204, member A
FLT4 fms-related tyrosine kinase 4
FMOD fibromodulin
FSD1 fibronectin type III and SPRY domain containing 1
GEMIN8 gem (nuclear organelle) associated protein 8
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
HDAC5 histone deacetylase 5
HIST1H4D histone cluster 1, H4d
HYI hydroxypyruvate isomerase (putative)
IL17RB interleukin 17 receptor B
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM5C lysine (K)-specific demethylase 5C
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MITF microphthalmia-associated transcription factor
MUTYH mutY homolog
MYO1F myosin IF
NARFL nuclear prelamin A recognition factor-like
NAT6 N-acetyltransferase 6 (GCN5-related)
NISCH nischarin
NOL12 nucleolar protein 12
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PNPLA6 patatin-like phospholipase domain containing 6
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRR14L proline rich 14-like
QPCT glutaminyl-peptide cyclotransferase
RAB3D RAB3D, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGS20 regulator of G-protein signaling 20
RHOG ras homolog family member G
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SENP7 SUMO1/sentrin specific peptidase 7
SHARPIN SHANK-associated RH domain interactor
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAI2 snail family zinc finger 2
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TCHH trichohyalin
TDRKH tudor and KH domain containing
TEP1 telomerase-associated protein 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM45A transmembrane protein 45A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
VASH2 vasohibin 2
ZBTB22 zinc finger and BTB domain containing 22
ZMAT5 zinc finger, matrin-type 5
ZNF219 zinc finger protein 219