haloperidol-5273 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the haloperidol-5273 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AKAP13 A kinase (PRKA) anchor protein 13
AKAP17A A kinase (PRKA) anchor protein 17A
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ATAT1 alpha tubulin acetyltransferase 1
ATP11A ATPase, class VI, type 11A
BCL2L2 BCL2-like 2
BTF3P11 basic transcription factor 3 pseudogene 11
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C17ORF53 chromosome 17 open reading frame 53
C21ORF2 chromosome 21 open reading frame 2
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAV2 caveolin 2
CCL27 chemokine (C-C motif) ligand 27
CCRL2 chemokine (C-C motif) receptor-like 2
CDK18 cyclin-dependent kinase 18
CDRT1 CMT1A duplicated region transcript 1
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CT62 cancer/testis antigen 62
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DGCR2 DiGeorge syndrome critical region gene 2
DGKQ diacylglycerol kinase, theta 110kDa
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DUSP10 dual specificity phosphatase 10
EDA ectodysplasin A
EFNB3 ephrin-B3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FBXO41 F-box protein 41
FLOT1 flotillin 1
FMO5 flavin containing monooxygenase 5
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFER growth factor, augmenter of liver regeneration
GFI1 growth factor independent 1 transcription repressor
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXA10 homeobox A10
HPS1 Hermansky-Pudlak syndrome 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
INPP5J inositol polyphosphate-5-phosphatase J
IRS2 insulin receptor substrate 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF2A kinesin heavy chain member 2A
KRT17 keratin 17, type I
LRP1B low density lipoprotein receptor-related protein 1B
MAP4 microtubule-associated protein 4
MEFV Mediterranean fever
MIP major intrinsic protein of lens fiber
MST1 macrophage stimulating 1
MYT1 myelin transcription factor 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPM3 nucleophosmin/nucleoplasmin 3
NRN1 neuritin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PBX2 pre-B-cell leukemia homeobox 2
PHF8 PHD finger protein 8
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
PLCD1 phospholipase C, delta 1
PPARA peroxisome proliferator-activated receptor alpha
PRDX2 peroxiredoxin 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTPRD protein tyrosine phosphatase, receptor type, D
PYY peptide YY
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RUNX1 runt-related transcription factor 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SFRP4 secreted frizzled-related protein 4
SH3BP2 SH3-domain binding protein 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35E2 solute carrier family 35, member E2
SLC39A9 solute carrier family 39, member 9
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNCAIP synuclein, alpha interacting protein
SNX29P2 sorting nexin 29 pseudogene 2
SPARCL1 SPARC-like 1 (hevin)
SRP72 signal recognition particle 72kDa
TBC1D22A TBC1 domain family, member 22A
TDRD12 tudor domain containing 12
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TTC38 tetratricopeptide repeat domain 38
TULP1 tubby like protein 1
UNC119 unc-119 homolog (C. elegans)
ZER1 zyg-11 related, cell cycle regulator
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD17B abhydrolase domain containing 17B
ACBD4 acyl-CoA binding domain containing 4
ADAP2 ArfGAP with dual PH domains 2
ADAT1 adenosine deaminase, tRNA-specific 1
ALPK1 alpha-kinase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C19ORF40 chromosome 19 open reading frame 40
C4ORF29 chromosome 4 open reading frame 29
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBX8 chromobox homolog 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK20 cyclin-dependent kinase 20
CEP295 centrosomal protein 295kDa
CHM choroideremia (Rab escort protein 1)
CSF1R colony stimulating factor 1 receptor
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF13 DDB1 and CUL4 associated factor 13
DENND4C DENN/MADD domain containing 4C
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DRD1 dopamine receptor D1
FAM63A family with sequence similarity 63, member A
GDAP1 ganglioside induced differentiation associated protein 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR1 G protein-coupled receptor 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H4F histone cluster 1, H4f
IDI2-AS1 IDI2 antisense RNA 1
IFT140 intraflagellar transport 140
IPP intracisternal A particle-promoted polypeptide
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP2 low density lipoprotein receptor-related protein 2
LRRC37A3 leucine rich repeat containing 37, member A3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBTD1 mbt domain containing 1
MYOZ3 myozenin 3
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NME5 NME/NM23 family member 5
OSGIN1 oxidative stress induced growth inhibitor 1
PARD6B par-6 family cell polarity regulator beta
PCDHA9 protocadherin alpha 9
PCDHB3 protocadherin beta 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHEX phosphate regulating endopeptidase homolog, X-linked
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCE protein kinase C, epsilon
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS53 protease, serine, 53
RAB3D RAB3D, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RPGRIP1L RPGRIP1-like
RPL13P5 ribosomal protein L13 pseudogene 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STIM1 stromal interaction molecule 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TESK1 testis-specific kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM19 transmembrane protein 19
TMEM242 transmembrane protein 242
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TTLL1 tubulin tyrosine ligase-like family member 1
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VEZT vezatin, adherens junctions transmembrane protein
VLDLR very low density lipoprotein receptor
WDR62 WD repeat domain 62
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF134 zinc finger protein 134
ZNF160 zinc finger protein 160
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721