haloperidol-5563 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the haloperidol-5563 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADD2 adducin 2 (beta)
AKAP13 A kinase (PRKA) anchor protein 13
ARHGAP4 Rho GTPase activating protein 4
ATN1 atrophin 1
ATP10B ATPase, class V, type 10B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BLZF1 basic leucine zipper nuclear factor 1
BMP8A bone morphogenetic protein 8a
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
C1QTNF1 C1q and tumor necrosis factor related protein 1
CA1 carbonic anhydrase I
CA5B carbonic anhydrase VB, mitochondrial
CADM4 cell adhesion molecule 4
CAV2 caveolin 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC25C cell division cycle 25C
CEND1 cell cycle exit and neuronal differentiation 1
CNTNAP2 contactin associated protein-like 2
COL19A1 collagen, type XIX, alpha 1
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CXCL6 chemokine (C-X-C motif) ligand 6
CYHR1 cysteine/histidine-rich 1
CYTH4 cytohesin 4
DLX2 distal-less homeobox 2
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRD1 dopamine receptor D1
EDNRA endothelin receptor type A
EHD2 EH-domain containing 2
EPX eosinophil peroxidase
FAM135A family with sequence similarity 135, member A
FAM163A family with sequence similarity 163, member A
FH fumarate hydratase
FN1 fibronectin 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GJA9 gap junction protein, alpha 9, 59kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GRM8 glutamate receptor, metabotropic 8
GTPBP1 GTP binding protein 1
HAP1 huntingtin-associated protein 1
HCG4 HLA complex group 4 (non-protein coding)
HDAC7 histone deacetylase 7
HPX hemopexin
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
ING2 inhibitor of growth family, member 2
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA1456 KIAA1456
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LINC00341 long intergenic non-protein coding RNA 341
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MLN motilin
MST1R macrophage stimulating 1 receptor
MUC3B mucin 3B, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCR2 natural cytotoxicity triggering receptor 2
NF1 neurofibromin 1
NNAT neuronatin
NOX1 NADPH oxidase 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PECAM1 platelet/endothelial cell adhesion molecule 1
PHF3 PHD finger protein 3
PLAC4 placenta-specific 4
PODNL1 podocan-like 1
PON3 paraoxonase 3
POPDC3 popeye domain containing 3
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRKCE protein kinase C, epsilon
PRND prion protein 2 (dublet)
PSAT1 phosphoserine aminotransferase 1
PTH1R parathyroid hormone 1 receptor
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOGA1 suppressor of glucose, autophagy associated 1
STEAP4 STEAP family member 4
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TMPRSS4 transmembrane protease, serine 4
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
YY2 YY2 transcription factor
ZNF37BP zinc finger protein 37B, pseudogene
ZNF407 zinc finger protein 407
ZNF415 zinc finger protein 415
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACBD4 acyl-CoA binding domain containing 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM adrenomedullin
AKAP12 A kinase (PRKA) anchor protein 12
ANO10 anoctamin 10
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BCAS1 breast carcinoma amplified sequence 1
BFSP1 beaded filament structural protein 1, filensin
C1ORF105 chromosome 1 open reading frame 105
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF54 chromosome 2 open reading frame 54
C5ORF45 chromosome 5 open reading frame 45
CCDC132 coiled-coil domain containing 132
CD82 CD82 molecule
CDK20 cyclin-dependent kinase 20
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CPSF3L cleavage and polyadenylation specific factor 3-like
CRLF1 cytokine receptor-like factor 1
DGKE diacylglycerol kinase, epsilon 64kDa
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
FAM189A2 family with sequence similarity 189, member A2
FBRS fibrosin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GMPR guanosine monophosphate reductase
HIST2H2AA3 histone cluster 2, H2aa3
IL15RA interleukin 15 receptor, alpha
IRF1 interferon regulatory factor 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLK5 kallikrein-related peptidase 5
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT15 keratin 15, type I
LIN7B lin-7 homolog B (C. elegans)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MTA2 metastasis associated 1 family, member 2
MUTYH mutY homolog
NIPAL2 NIPA-like domain containing 2
NRGN neurogranin (protein kinase C substrate, RC3)
NT5DC3 5'-nucleotidase domain containing 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI1 peptidyl arginine deiminase, type I
PCDHA9 protocadherin alpha 9
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PRPH peripherin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB30 RAB30, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS19 regulator of G-protein signaling 19
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A4 S100 calcium binding protein A4
SAMD9 sterile alpha motif domain containing 9
SDC3 syndecan 3
SH2B3 SH2B adaptor protein 3
SLIT2 slit homolog 2 (Drosophila)
SLMO1 slowmo homolog 1 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SMAGP small cell adhesion glycoprotein
SPATA2L spermatogenesis associated 2-like
TARP TCR gamma alternate reading frame protein
THOP1 thimet oligopeptidase 1
TMEM120B transmembrane protein 120B
TMEM57 transmembrane protein 57
TTC23 tetratricopeptide repeat domain 23
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VIM vimentin
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
ZBTB44 zinc finger and BTB domain containing 44
ZNF408 zinc finger protein 408
ZNF696 zinc finger protein 696
ZNF787 zinc finger protein 787