haloperidol-5638 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the haloperidol-5638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRL3 adhesion G protein-coupled receptor L3
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALK anaplastic lymphoma receptor tyrosine kinase
AOC2 amine oxidase, copper containing 2 (retina-specific)
ATN1 atrophin 1
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
BTNL3 butyrophilin-like 3
C2ORF27A chromosome 2 open reading frame 27A
C3AR1 complement component 3a receptor 1
C9ORF9 chromosome 9 open reading frame 9
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CARD14 caspase recruitment domain family, member 14
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCK cholecystokinin
CD47 CD47 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK18 cyclin-dependent kinase 18
CDKN2A cyclin-dependent kinase inhibitor 2A
CFHR4 complement factor H-related 4
COL13A1 collagen, type XIII, alpha 1
CUL7 cullin 7
CYLD cylindromatosis (turban tumor syndrome)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCTN1 dynactin 1
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
DMPK dystrophia myotonica-protein kinase
FAM212B family with sequence similarity 212, member B
FAM214B family with sequence similarity 214, member B
FGF13 fibroblast growth factor 13
FGF22 fibroblast growth factor 22
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FRZB frizzled-related protein
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAS1 growth arrest-specific 1
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GEMIN7 gem (nuclear organelle) associated protein 7
GLYAT glycine-N-acyltransferase
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTA4 glutathione S-transferase alpha 4
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA11 homeobox A11
HOXB5 homeobox B5
HPX hemopexin
ING4 inhibitor of growth family, member 4
INSIG1 insulin induced gene 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAM3 junctional adhesion molecule 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD12 potassium channel tetramerization domain containing 12
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
KSR1 kinase suppressor of ras 1
LDB3 LIM domain binding 3
LDHB lactate dehydrogenase B
LIN7A lin-7 homolog A (C. elegans)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGEA3 melanoma antigen family A3
MDFI MyoD family inhibitor
MFSD7 major facilitator superfamily domain containing 7
MMP25 matrix metallopeptidase 25
MPL MPL proto-oncogene, thrombopoietin receptor
NEK9 NIMA-related kinase 9
OCLM oculomedin
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDLIM4 PDZ and LIM domain 4
PECAM1 platelet/endothelial cell adhesion molecule 1
PER1 period circadian clock 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPARD peroxisome proliferator-activated receptor delta
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PSAT1 phosphoserine aminotransferase 1
PTHLH parathyroid hormone-like hormone
RASAL1 RAS protein activator like 1 (GAP1 like)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPAP1 RNA polymerase II associated protein 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRSF7 serine/arginine-rich splicing factor 7
SYN2 synapsin II
TNC tenascin C
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
UBE3A ubiquitin protein ligase E3A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UMPS uridine monophosphate synthetase
VIM vimentin
WBP5 WW domain binding protein 5
XIST X inactive specific transcript (non-protein coding)
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ATAT1 alpha tubulin acetyltransferase 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP15 bone morphogenetic protein 15
C2ORF54 chromosome 2 open reading frame 54
CARF calcium responsive transcription factor
CCDC134 coiled-coil domain containing 134
CDON cell adhesion associated, oncogene regulated
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLEC4E C-type lectin domain family 4, member E
CLIC2 chloride intracellular channel 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
DMTN dematin actin binding protein
DOK5 docking protein 5
DPY19L1P1 DPY19L1 pseudogene 1
DRD1 dopamine receptor D1
EPX eosinophil peroxidase
ETNK2 ethanolamine kinase 2
F2R coagulation factor II (thrombin) receptor
F9 coagulation factor IX
FAM110B family with sequence similarity 110, member B
FAM184A family with sequence similarity 184, member A
FCHO1 FCH domain only 1
FGF6 fibroblast growth factor 6
FLCN folliculin
FRMD1 FERM domain containing 1
GAMT guanidinoacetate N-methyltransferase
GFI1 growth factor independent 1 transcription repressor
GJA8 gap junction protein, alpha 8, 50kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H2AJ histone cluster 1, H2aj
HMHB1 histocompatibility (minor) HB-1
HOXA4 homeobox A4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IBSP integrin-binding sialoprotein
IGSF6 immunoglobulin superfamily, member 6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ITGA8 integrin, alpha 8
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIAA0754 KIAA0754
KIAA1456 KIAA1456
KRT15 keratin 15, type I
LAMP3 lysosomal-associated membrane protein 3
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC257152 uncharacterized LOC257152
LOC729164 hCG1732469
LPPR1 lipid phosphate phosphatase-related protein type 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MSI1 musashi RNA-binding protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPR3 natriuretic peptide receptor 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OVOL1 ovo-like zinc finger 1
PCDHB13 protocadherin beta 13
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8B phosphodiesterase 8B
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PODNL1 podocan-like 1
POU4F2 POU class 4 homeobox 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFXAP regulatory factor X-associated protein
RIN1 Ras and Rab interactor 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SDC3 syndecan 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SNTA1 syntrophin, alpha 1
SSBP3 single stranded DNA binding protein 3
SSTR4 somatostatin receptor 4
STARD3 StAR-related lipid transfer (START) domain containing 3
STRA6 stimulated by retinoic acid 6
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SULT4A1 sulfotransferase family 4A, member 1
TMEM121 transmembrane protein 121
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TTLL1 tubulin tyrosine ligase-like family member 1
ZNF205 zinc finger protein 205
ZNF34 zinc finger protein 34
ZNF41 zinc finger protein 41
ZNF446 zinc finger protein 446
ZNF484 zinc finger protein 484
ZNF506 zinc finger protein 506
ZNF711 zinc finger protein 711
ZNF750 zinc finger protein 750
ZNF862 zinc finger protein 862