haloperidol-6163 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the haloperidol-6163 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA2P3 annexin A2 pseudogene 3
AQP9 aquaporin 9
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATN1 atrophin 1
ATP10A ATPase, class V, type 10A
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B9D1 B9 protein domain 1
BCAS1 breast carcinoma amplified sequence 1
BCL2 B-cell CLL/lymphoma 2
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C5ORF45 chromosome 5 open reading frame 45
CALCR calcitonin receptor
CAPN9 calpain 9
CDC14A cell division cycle 14A
CDK10 cyclin-dependent kinase 10
CLDN3 claudin 3
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A1 collagen, type I, alpha 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOCK6 dedicator of cytokinesis 6
DRD2 dopamine receptor D2
ETV1 ets variant 1
F2R coagulation factor II (thrombin) receptor
FAS Fas cell surface death receptor
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAS1 growth arrest-specific 1
GJA1 gap junction protein, alpha 1, 43kDa
GK2 glycerol kinase 2
GUK1 guanylate kinase 1
HNMT histamine N-methyltransferase
HOXA10 homeobox A10
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HYAL1 hyaluronoglucosaminidase 1
IL16 interleukin 16
IL22RA1 interleukin 22 receptor, alpha 1
IQSEC1 IQ motif and Sec7 domain 1
ITGB5 integrin, beta 5
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLF12 Kruppel-like factor 12
KLHL36 kelch-like family member 36
LBP lipopolysaccharide binding protein
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MST1 macrophage stimulating 1
MUC3A mucin 3A, cell surface associated
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NIPAL2 NIPA-like domain containing 2
NOD2 nucleotide-binding oligomerization domain containing 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
ONECUT2 one cut homeobox 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARP3 poly (ADP-ribose) polymerase family, member 3
PDCD6 programmed cell death 6
PDE10A phosphodiesterase 10A
PEX11A peroxisomal biogenesis factor 11 alpha
PHEX phosphate regulating endopeptidase homolog, X-linked
PLD3 phospholipase D family, member 3
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POU2F3 POU class 2 homeobox 3
PRDM10 PR domain containing 10
RAB7A RAB7A, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPL10L ribosomal protein L10-like
SH3BGR SH3 domain binding glutamate-rich protein
SH3BP2 SH3-domain binding protein 2
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMIM14 small integral membrane protein 14
SOCS3 suppressor of cytokine signaling 3
SOX10 SRY (sex determining region Y)-box 10
SPAG6 sperm associated antigen 6
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SYCE1L synaptonemal complex central element protein 1-like
SYNDIG1 synapse differentiation inducing 1
TBRG4 transforming growth factor beta regulator 4
TCP10 t-complex 10
TFF2 trefoil factor 2
TIMELESS timeless circadian clock
TRIM23 tripartite motif containing 23
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UBE3A ubiquitin protein ligase E3A
ULBP1 UL16 binding protein 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZFHX2 zinc finger homeobox 2
ZNF154 zinc finger protein 154
ZNF254 zinc finger protein 254
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACP6 acid phosphatase 6, lysophosphatidic
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE1 adhesion G protein-coupled receptor E1
AGBL5 ATP/GTP binding protein-like 5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKTIP AKT interacting protein
AMT aminomethyltransferase
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATXN2L ataxin 2-like
BAHD1 bromo adjacent homology domain containing 1
C5 complement component 5
CDR2L cerebellar degeneration-related protein 2-like
CHPF chondroitin polymerizing factor
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CTAGE9 CTAGE family, member 9
DDN dendrin
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNMBP dynamin binding protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP8 dual specificity phosphatase 8
EGR2 early growth response 2
EIF5A2 eukaryotic translation initiation factor 5A2
ERCC6 excision repair cross-complementation group 6
FAM188A family with sequence similarity 188, member A
FAM86B1 family with sequence similarity 86, member B1
GAA glucosidase, alpha; acid
GEMIN8 gem (nuclear organelle) associated protein 8
GLCE glucuronic acid epimerase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GPR35 G protein-coupled receptor 35
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1B histone cluster 1, H1b
HLA-DMB major histocompatibility complex, class II, DM beta
IFI44L interferon-induced protein 44-like
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
KATNBL1 katanin p80 subunit B-like 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KLRG1 killer cell lectin-like receptor subfamily G, member 1
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMB3 laminin, beta 3
LIN7B lin-7 homolog B (C. elegans)
LRP5 low density lipoprotein receptor-related protein 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPKBP1 mitogen-activated protein kinase binding protein 1
MATK megakaryocyte-associated tyrosine kinase
MEFV Mediterranean fever
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRAS muscle RAS oncogene homolog
MTA2 metastasis associated 1 family, member 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
MYO15A myosin XVA
NT5M 5',3'-nucleotidase, mitochondrial
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PFN2 profilin 2
PGPEP1 pyroglutamyl-peptidase I
PITX2 paired-like homeodomain 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMP22 peripheral myelin protein 22
PNOC prepronociceptin
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPRS protein tyrosine phosphatase, receptor type, S
PWAR5 Prader Willi/Angelman region RNA 5
PYGB phosphorylase, glycogen; brain
RAB3A RAB3A, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIN2 Ras and Rab interactor 2
RPL23AP32 ribosomal protein L23a pseudogene 32
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC31B SEC31 homolog B (S. cerevisiae)
SLC16A6 solute carrier family 16, member 6
SLC35F6 solute carrier family 35, member F6
SNAI1 snail family zinc finger 1
SNHG20 small nucleolar RNA host gene 20
SPATA20 spermatogenesis associated 20
SREBF1 sterol regulatory element binding transcription factor 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TET3 tet methylcytosine dioxygenase 3
THAP7 THAP domain containing 7
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM62 transmembrane protein 62
TRAF1 TNF receptor-associated factor 1
TUBA3C tubulin, alpha 3c
ULK1 unc-51 like autophagy activating kinase 1
UPB1 ureidopropionase, beta
URGCP upregulator of cell proliferation
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZDHHC14 zinc finger, DHHC-type containing 14
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF701 zinc finger protein 701
ZNF76 zinc finger protein 76