harmaline-6623 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the harmaline-6623 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACVR1B activin A receptor, type IB
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY9 adenylate cyclase 9
ALK anaplastic lymphoma receptor tyrosine kinase
APOE apolipoprotein E
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATAD5 ATPase family, AAA domain containing 5
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BTG2 BTG family, member 2
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
CADM3 cell adhesion molecule 3
CADM4 cell adhesion molecule 4
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC121 coiled-coil domain containing 121
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFH complement factor H
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CRP C-reactive protein, pentraxin-related
DENND2A DENN/MADD domain containing 2A
DLX4 distal-less homeobox 4
EPAS1 endothelial PAS domain protein 1
FAM46C family with sequence similarity 46, member C
FASLG Fas ligand (TNF superfamily, member 6)
FBXL15 F-box and leucine-rich repeat protein 15
FBXO21 F-box protein 21
FCMR Fc fragment of IgM receptor
FHIT fragile histidine triad
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FN1 fibronectin 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAS2 growth arrest-specific 2
GREM1 gremlin 1, DAN family BMP antagonist
GRIA1 glutamate receptor, ionotropic, AMPA 1
HOXC10 homeobox C10
ICOSLG inducible T-cell co-stimulator ligand
IFT122 intraflagellar transport 122
IL17RB interleukin 17 receptor B
KIAA1024 KIAA1024
KLF3 Kruppel-like factor 3 (basic)
KRT17 keratin 17, type I
LIMD2 LIM domain containing 2
LMNB1 lamin B1
LOC390998 ribosomal protein L10 pseudogene
MAGEA5 melanoma antigen family A5
MEFV Mediterranean fever
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MTCP1 mature T-cell proliferation 1
NACAD NAC alpha domain containing
NCF4 neutrophil cytosolic factor 4, 40kDa
NPC1 Niemann-Pick disease, type C1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDH9 protocadherin 9
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM1 PR domain containing 1, with ZNF domain
PROL1 proline rich, lacrimal 1
PTCRA pre T-cell antigen receptor alpha
PTN pleiotrophin
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS4 regulator of G-protein signaling 4
SDS serine dehydratase
SH3BP2 SH3-domain binding protein 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOS2 son of sevenless homolog 2 (Drosophila)
SPN sialophorin
SPON1 spondin 1, extracellular matrix protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
THBD thrombomodulin
THEMIS2 thymocyte selection associated family member 2
TLK1 tousled-like kinase 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TWISTNB TWIST neighbor
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
USP46 ubiquitin specific peptidase 46
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WAS Wiskott-Aldrich syndrome
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF24 zinc finger protein 24
ZNF280B zinc finger protein 280B
ZNF334 zinc finger protein 334
ZNF609 zinc finger protein 609
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
BTBD2 BTB (POZ) domain containing 2
BTC betacellulin
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CDKL3 cyclin-dependent kinase-like 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CENPT centromere protein T
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CORT cortistatin
CST1 cystatin SN
DDN dendrin
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLK2 delta-like 2 homolog (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
ELP6 elongator acetyltransferase complex subunit 6
FA2H fatty acid 2-hydroxylase
FLJ21369 uncharacterized protein FLJ21369
GAS8 growth arrest-specific 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GPR1 G protein-coupled receptor 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AK histone cluster 1, H2ak
HSPA2 heat shock 70kDa protein 2
IL7R interleukin 7 receptor
IPO8 importin 8
ITPKC inositol-trisphosphate 3-kinase C
KIAA1456 KIAA1456
LAMC3 laminin, gamma 3
LAX1 lymphocyte transmembrane adaptor 1
LRRC37A3 leucine rich repeat containing 37, member A3
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICALL2 MICAL-like 2
MOGS mannosyl-oligosaccharide glucosidase
MON1B MON1 secretory trafficking family member B
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MYOZ3 myozenin 3
NAG18 NAG18 mRNA
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
NT5M 5',3'-nucleotidase, mitochondrial
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLXNB3 plexin B3
POM121 POM121 transmembrane nucleoporin
POR P450 (cytochrome) oxidoreductase
PRB3 proline-rich protein BstNI subfamily 3
PRR15L proline rich 15-like
PRSS8 protease, serine, 8
PWAR5 Prader Willi/Angelman region RNA 5
RAB4B RAB4B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS17 regulator of G-protein signaling 17
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGRIP1L RPGRIP1-like
SCIN scinderin
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIX3 SIX homeobox 3
SLC16A6 solute carrier family 16, member 6
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMCC2 transmembrane and coiled-coil domain family 2
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
VWA1 von Willebrand factor A domain containing 1
WDR25 WD repeat domain 25
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF222 zinc finger protein 222
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF385D zinc finger protein 385D
ZNF528 zinc finger protein 528
ZNF652 zinc finger protein 652
ZNF667 zinc finger protein 667
ZNF767P zinc finger family member 767, pseudogene
ZNF768 zinc finger protein 768