| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the harman-4584 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACRV1 | acrosomal vesicle protein 1 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| AGFG2 | ArfGAP with FG repeats 2 |
| APC | adenomatous polyposis coli |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASTN2 | astrotactin 2 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CAV2 | caveolin 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CIB2 | calcium and integrin binding family member 2 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL5A1 | collagen, type V, alpha 1 |
| CREM | cAMP responsive element modulator |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| DCN | decorin |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ERGIC3 | ERGIC and golgi 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FN1 | fibronectin 1 |
| GAB1 | GRB2-associated binding protein 1 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXC5 | homeobox C5 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 |
| ING2 | inhibitor of growth family, member 2 |
| KIAA0040 | KIAA0040 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LRRC48 | leucine rich repeat containing 48 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MKRN3 | makorin ring finger protein 3 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYOZ3 | myozenin 3 |
| NEK9 | NIMA-related kinase 9 |
| NNMT | nicotinamide N-methyltransferase |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NRP2 | neuropilin 2 |
| OPRL1 | opiate receptor-like 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHOX2A | paired-like homeobox 2a |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| POU5F1B | POU class 5 homeobox 1B |
| PRAMEF11 | PRAME family member 11 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB3D | RAB3D, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RASA3 | RAS p21 protein activator 3 |
| RASAL2 | RAS protein activator like 2 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SIRT4 | sirtuin 4 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLIT1 | slit homolog 1 (Drosophila) |
| SMAD6 | SMAD family member 6 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNX13 | sorting nexin 13 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STRN | striatin, calmodulin binding protein |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULF1 | sulfatase 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TBX6 | T-box 6 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TSFM | Ts translation elongation factor, mitochondrial |
| TSPAN9 | tetraspanin 9 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VCAN | versican |
| VWA5A | von Willebrand factor A domain containing 5A |
| WFDC2 | WAP four-disulfide core domain 2 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADCY7 | adenylate cyclase 7 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASZ1 | castor zinc finger 1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CES3 | carboxylesterase 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNTLN | centlein, centrosomal protein |
| COL21A1 | collagen, type XXI, alpha 1 |
| CRYBA2 | crystallin, beta A2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DENND2D | DENN/MADD domain containing 2D |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FUZ | fuzzy planar cell polarity protein |
| GAS8 | growth arrest-specific 8 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFT54 | intraflagellar transport 54 |
| IL7 | interleukin 7 |
| KIAA1107 | KIAA1107 |
| KRT86 | keratin 86, type II |
| LHX6 | LIM homeobox 6 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNB1 | lamin B1 |
| LMTK1 | lemur tail kinase 1 |
| LOC730101 | uncharacterized LOC730101 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MDFI | MyoD family inhibitor |
| MEGF8 | multiple EGF-like-domains 8 |
| MLYCD | malonyl-CoA decarboxylase |
| MOB3B | MOB kinase activator 3B |
| MON1B | MON1 secretory trafficking family member B |
| MVP | major vault protein |
| NABP1 | nucleic acid binding protein 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NID2 | nidogen 2 (osteonidogen) |
| NINJ1 | ninjurin 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSMR | oncostatin M receptor |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLA2G15 | phospholipase A2, group XV |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PROX1 | prospero homeobox 1 |
| PRR7 | proline rich 7 (synaptic) |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB36 | RAB36, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RIN1 | Ras and Rab interactor 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNGR3 | synaptogyrin 3 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TMEM180 | transmembrane protein 180 |
| TNS2 | tensin 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF343 | zinc finger protein 343 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF623 | zinc finger protein 623 |
| ZNF671 | zinc finger protein 671 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |