harmine-2750 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the harmine-2750 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ACTA2 actin, alpha 2, smooth muscle, aorta
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ALDOB aldolase B, fructose-bisphosphate
APOLD1 apolipoprotein L domain containing 1
ATF3 activating transcription factor 3
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BCAN brevican
BTG2 BTG family, member 2
CCL13 chemokine (C-C motif) ligand 13
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN15 claudin 15
CLEC4E C-type lectin domain family 4, member E
CRYGC crystallin, gamma C
CTSF cathepsin F
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
EFR3B EFR3 homolog B (S. cerevisiae)
EML2 echinoderm microtubule associated protein like 2
FAS Fas cell surface death receptor
FAXDC2 fatty acid hydroxylase domain containing 2
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GGT1 gamma-glutamyltransferase 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR182 G protein-coupled receptor 182
GPR87 G protein-coupled receptor 87
GUCA1B guanylate cyclase activator 1B (retina)
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HIST2H2AA3 histone cluster 2, H2aa3
HRH2 histamine receptor H2
IL11RA interleukin 11 receptor, alpha
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KAT6A K(lysine) acetyltransferase 6A
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KREMEN2 kringle containing transmembrane protein 2
LENEP lens epithelial protein
LIF leukemia inhibitory factor
LINC00216 long intergenic non-protein coding RNA 216
LOC157562 uncharacterized LOC157562
LTB4R leukotriene B4 receptor
MAP4 microtubule-associated protein 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED31 mediator complex subunit 31
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MLN motilin
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MST1 macrophage stimulating 1
MYH11 myosin, heavy chain 11, smooth muscle
MYL10 myosin, light chain 10, regulatory
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP2L2 NEDD4 binding protein 2-like 2
NHLH2 nescient helix loop helix 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPR1 natriuretic peptide receptor 1
NPR3 natriuretic peptide receptor 3
NRSN2 neurensin 2
NSUN6 NOP2/Sun domain family, member 6
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OVGP1 oviductal glycoprotein 1, 120kDa
PLAC4 placenta-specific 4
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODNL1 podocan-like 1
PPP5C protein phosphatase 5, catalytic subunit
PRDM2 PR domain containing 2, with ZNF domain
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
RAD54L2 RAD54-like 2 (S. cerevisiae)
RDH16 retinol dehydrogenase 16 (all-trans)
RGS5 regulator of G-protein signaling 5
RPL31 ribosomal protein L31
RPS11 ribosomal protein S11
RSL1D1 ribosomal L1 domain containing 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SARM1 sterile alpha and TIR motif containing 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SESN1 sestrin 1
SH2D3A SH2 domain containing 3A
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLN sarcolipin
SMIM7 small integral membrane protein 7
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAAR5 trace amine associated receptor 5
TAPBP TAP binding protein (tapasin)
TAS2R1 taste receptor, type 2, member 1
TAT tyrosine aminotransferase
TBCD tubulin folding cofactor D
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THRB thyroid hormone receptor, beta
TLX3 T-cell leukemia homeobox 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
UCN urocortin
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF3 zinc finger protein 3
ZNF606 zinc finger protein 606
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACVR1 activin A receptor, type I
ADCY6 adenylate cyclase 6
ARMCX5 armadillo repeat containing, X-linked 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BEX4 brain expressed, X-linked 4
C12ORF4 chromosome 12 open reading frame 4
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C9ORF91 chromosome 9 open reading frame 91
CBR3 carbonyl reductase 3
CDC37L1 cell division cycle 37-like 1
CENPI centromere protein I
CLEC16A C-type lectin domain family 16, member A
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CPTP ceramide-1-phosphate transfer protein
CRY1 cryptochrome circadian clock 1
CTPS1 CTP synthase 1
DDIT3 DNA-damage-inducible transcript 3
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DTWD1 DTW domain containing 1
EAF2 ELL associated factor 2
FANCL Fanconi anemia, complementation group L
FHOD1 formin homology 2 domain containing 1
FOXD1 forkhead box D1
FOXK2 forkhead box K2
GCA grancalcin, EF-hand calcium binding protein
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLMN glomulin, FKBP associated protein
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA14 heat shock 70kDa protein 14
HSPA2 heat shock 70kDa protein 2
KCTD20 potassium channel tetramerization domain containing 20
KIAA0020 KIAA0020
KIAA0895 KIAA0895
KIF11 kinesin family member 11
KIF16B kinesin family member 16B
LMBRD1 LMBR1 domain containing 1
MAGEF1 melanoma antigen family F1
MED4 mediator complex subunit 4
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MNS1 meiosis-specific nuclear structural 1
MRPS31 mitochondrial ribosomal protein S31
MSL1 male-specific lethal 1 homolog (Drosophila)
MTMR6 myotubularin related protein 6
NLK nemo-like kinase
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOL8 nucleolar protein 8
NPY1R neuropeptide Y receptor Y1
OFD1 oral-facial-digital syndrome 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCTP phosphatidylcholine transfer protein
PDZRN3 PDZ domain containing ring finger 3
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PMM2 phosphomannomutase 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POMT1 protein-O-mannosyltransferase 1
PP14571 uncharacterized LOC100130449
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRR3 proline rich 3
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB23 RAB23, member RAS oncogene family
RAI14 retinoic acid induced 14
RBM12 RNA binding motif protein 12
RBM28 RNA binding motif protein 28
RBM4B RNA binding motif protein 4B
RNFT1 ring finger protein, transmembrane 1
RPAP3 RNA polymerase II associated protein 3
SCAF8 SR-related CTD-associated factor 8
SFMBT1 Scm-like with four mbt domains 1
SLC35A5 solute carrier family 35, member A5
SNUPN snurportin 1
SOAT1 sterol O-acyltransferase 1
SPAST spastin
SPC25 SPC25, NDC80 kinetochore complex component
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIPIN TIMELESS interacting protein
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM13 tripartite motif containing 13
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRMT61B tRNA methyltransferase 61B
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TUBGCP5 tubulin, gamma complex associated protein 5
UBA2 ubiquitin-like modifier activating enzyme 2
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP6 ubiquitin specific peptidase 6
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR44 WD repeat domain 44
WDR7 WD repeat domain 7
WWC2 WW and C2 domain containing 2
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF165 zinc finger protein 165
ZNF184 zinc finger protein 184
ZNF652 zinc finger protein 652