| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the harmine-2750 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATF3 | activating transcription factor 3 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| BCAN | brevican |
| BTG2 | BTG family, member 2 |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLDN15 | claudin 15 |
| CLEC4E | C-type lectin domain family 4, member E |
| CRYGC | crystallin, gamma C |
| CTSF | cathepsin F |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EML2 | echinoderm microtubule associated protein like 2 |
| FAS | Fas cell surface death receptor |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GGT1 | gamma-glutamyltransferase 1 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR182 | G protein-coupled receptor 182 |
| GPR87 | G protein-coupled receptor 87 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HRH2 | histamine receptor H2 |
| IL11RA | interleukin 11 receptor, alpha |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LENEP | lens epithelial protein |
| LIF | leukemia inhibitory factor |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LOC157562 | uncharacterized LOC157562 |
| LTB4R | leukotriene B4 receptor |
| MAP4 | microtubule-associated protein 4 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED31 | mediator complex subunit 31 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MLN | motilin |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NHLH2 | nescient helix loop helix 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPR1 | natriuretic peptide receptor 1 |
| NPR3 | natriuretic peptide receptor 3 |
| NRSN2 | neurensin 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PLAC4 | placenta-specific 4 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PODNL1 | podocan-like 1 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PTEN | phosphatase and tensin homolog |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RGS5 | regulator of G-protein signaling 5 |
| RPL31 | ribosomal protein L31 |
| RPS11 | ribosomal protein S11 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SESN1 | sestrin 1 |
| SH2D3A | SH2 domain containing 3A |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLN | sarcolipin |
| SMIM7 | small integral membrane protein 7 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAAR5 | trace amine associated receptor 5 |
| TAPBP | TAP binding protein (tapasin) |
| TAS2R1 | taste receptor, type 2, member 1 |
| TAT | tyrosine aminotransferase |
| TBCD | tubulin folding cofactor D |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THRB | thyroid hormone receptor, beta |
| TLX3 | T-cell leukemia homeobox 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| UCN | urocortin |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF3 | zinc finger protein 3 |
| ZNF606 | zinc finger protein 606 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACVR1 | activin A receptor, type I |
| ADCY6 | adenylate cyclase 6 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BEX4 | brain expressed, X-linked 4 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CBR3 | carbonyl reductase 3 |
| CDC37L1 | cell division cycle 37-like 1 |
| CENPI | centromere protein I |
| CLEC16A | C-type lectin domain family 16, member A |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CPTP | ceramide-1-phosphate transfer protein |
| CRY1 | cryptochrome circadian clock 1 |
| CTPS1 | CTP synthase 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DTWD1 | DTW domain containing 1 |
| EAF2 | ELL associated factor 2 |
| FANCL | Fanconi anemia, complementation group L |
| FHOD1 | formin homology 2 domain containing 1 |
| FOXD1 | forkhead box D1 |
| FOXK2 | forkhead box K2 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLMN | glomulin, FKBP associated protein |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPA14 | heat shock 70kDa protein 14 |
| HSPA2 | heat shock 70kDa protein 2 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0020 | KIAA0020 |
| KIAA0895 | KIAA0895 |
| KIF11 | kinesin family member 11 |
| KIF16B | kinesin family member 16B |
| LMBRD1 | LMBR1 domain containing 1 |
| MAGEF1 | melanoma antigen family F1 |
| MED4 | mediator complex subunit 4 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MNS1 | meiosis-specific nuclear structural 1 |
| MRPS31 | mitochondrial ribosomal protein S31 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MTMR6 | myotubularin related protein 6 |
| NLK | nemo-like kinase |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOL8 | nucleolar protein 8 |
| NPY1R | neuropeptide Y receptor Y1 |
| OFD1 | oral-facial-digital syndrome 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PCTP | phosphatidylcholine transfer protein |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PMM2 | phosphomannomutase 2 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| POMT1 | protein-O-mannosyltransferase 1 |
| PP14571 | uncharacterized LOC100130449 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRR3 | proline rich 3 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB23 | RAB23, member RAS oncogene family |
| RAI14 | retinoic acid induced 14 |
| RBM12 | RNA binding motif protein 12 |
| RBM28 | RNA binding motif protein 28 |
| RBM4B | RNA binding motif protein 4B |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPAP3 | RNA polymerase II associated protein 3 |
| SCAF8 | SR-related CTD-associated factor 8 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SLC35A5 | solute carrier family 35, member A5 |
| SNUPN | snurportin 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPAST | spastin |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TIPIN | TIMELESS interacting protein |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM13 | tripartite motif containing 13 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TRMT61B | tRNA methyltransferase 61B |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) |
| USP6 | ubiquitin specific peptidase 6 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR44 | WD repeat domain 44 |
| WDR7 | WD repeat domain 7 |
| WWC2 | WW and C2 domain containing 2 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZNF165 | zinc finger protein 165 |
| ZNF184 | zinc finger protein 184 |
| ZNF652 | zinc finger protein 652 |
