harmine-5855 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the harmine-5855 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADRBK2 adrenergic, beta, receptor kinase 2
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ANKRD10 ankyrin repeat domain 10
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP10B ATPase, class V, type 10B
AURKC aurora kinase C
BAAT bile acid CoA:amino acid N-acyltransferase
BICD1 bicaudal D homolog 1 (Drosophila)
BIRC5 baculoviral IAP repeat containing 5
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTBD18 BTB (POZ) domain containing 18
C2CD2L C2CD2-like
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBX5 chromobox homolog 5
CDK13 cyclin-dependent kinase 13
CDKL3 cyclin-dependent kinase-like 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL14A1 collagen, type XIV, alpha 1
COL1A1 collagen, type I, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CREM cAMP responsive element modulator
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTSF cathepsin F
CXCL6 chemokine (C-X-C motif) ligand 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DPF3 D4, zinc and double PHD fingers, family 3
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EGR1 early growth response 1
FGF18 fibroblast growth factor 18
FST follistatin
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GP6 glycoprotein VI (platelet)
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GTF2I general transcription factor IIi
HBS1L HBS1-like translational GTPase
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HMGN5 high mobility group nucleosome binding domain 5
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXA11 homeobox A11
HOXB7 homeobox B7
IL16 interleukin 16
INHBA inhibin, beta A
INPP5J inositol polyphosphate-5-phosphatase J
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM5C lysine (K)-specific demethylase 5C
KRT86 keratin 86, type II
LEFTY1 left-right determination factor 1
LHX1 LIM homeobox 1
LMF2 lipase maturation factor 2
LOC157562 uncharacterized LOC157562
LOC257152 uncharacterized LOC257152
LRP4 low density lipoprotein receptor-related protein 4
MAPK7 mitogen-activated protein kinase 7
MED18 mediator complex subunit 18
MEG3 maternally expressed 3 (non-protein coding)
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MORC1 MORC family CW-type zinc finger 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MUC1 mucin 1, cell surface associated
MYH14 myosin, heavy chain 14, non-muscle
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP2L2 NEDD4 binding protein 2-like 2
NGDN neuroguidin, EIF4E binding protein
NRXN3 neurexin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PCDHB12 protocadherin beta 12
PDE4DIP phosphodiesterase 4D interacting protein
PLD3 phospholipase D family, member 3
PLXNA2 plexin A2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRPF18 pre-mRNA processing factor 18
PRSS8 protease, serine, 8
PVR poliovirus receptor
PVT1 Pvt1 oncogene (non-protein coding)
RFPL3S RFPL3 antisense
ROM1 retinal outer segment membrane protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
SCG5 secretogranin V
SELPLG selectin P ligand
SKIL SKI-like proto-oncogene
SMC4 structural maintenance of chromosomes 4
SOX30 SRY (sex determining region Y)-box 30
STATH statherin
STS steroid sulfatase (microsomal), isozyme S
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TLE4 transducin-like enhancer of split 4
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
UBA7 ubiquitin-like modifier activating enzyme 7
WIPF1 WAS/WASL interacting protein family, member 1
ZBTB1 zinc finger and BTB domain containing 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF500 zinc finger protein 500
ZNF606 zinc finger protein 606

decreased expression

Symbol Name
ACVR1 activin A receptor, type I
ADRB2 adrenoceptor beta 2, surface
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMCX5 armadillo repeat containing, X-linked 5
BET1 Bet1 golgi vesicular membrane trafficking protein
C12ORF4 chromosome 12 open reading frame 4
C16ORF59 chromosome 16 open reading frame 59
CENPE centromere protein E, 312kDa
CEP70 centrosomal protein 70kDa
CHST10 carbohydrate sulfotransferase 10
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CRYBG3 beta-gamma crystallin domain containing 3
CTPS1 CTP synthase 1
CUEDC1 CUE domain containing 1
CUTC cutC copper transporter
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCAF16 DDB1 and CUL4 associated factor 16
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNMBP dynamin binding protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
F3 coagulation factor III (thromboplastin, tissue factor)
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FZD7 frizzled class receptor 7
GHR growth hormone receptor
GID4 GID complex subunit 4
GPHN gephyrin
GPR87 G protein-coupled receptor 87
H1F0 H1 histone family, member 0
HCFC2 host cell factor C2
HEATR3 HEAT repeat containing 3
HMHA1 histocompatibility (minor) HA-1
HYAL2 hyaluronoglucosaminidase 2
KIF20B kinesin family member 20B
KIN Kin17 DNA and RNA binding protein
KIZ kizuna centrosomal protein
LOC730101 uncharacterized LOC730101
MAGEH1 melanoma antigen family H1
MCOLN1 mucolipin 1
MEIS1 Meis homeobox 1
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MST1R macrophage stimulating 1 receptor
MSX1 msh homeobox 1
MT1H metallothionein 1H
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAP1L2 nucleosome assembly protein 1-like 2
NAP1L3 nucleosome assembly protein 1-like 3
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOL8 nucleolar protein 8
NPM3 nucleophosmin/nucleoplasmin 3
NSUN3 NOP2/Sun domain family, member 3
NVL nuclear VCP-like
OFD1 oral-facial-digital syndrome 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PEX2 peroxisomal biogenesis factor 2
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLAU plasminogen activator, urokinase
PLEKHA5 pleckstrin homology domain containing, family A member 5
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPT2 palmitoyl-protein thioesterase 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PXDC1 PX domain containing 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RBM12 RNA binding motif protein 12
RCOR3 REST corepressor 3
RNF121 ring finger protein 121
RSAD1 radical S-adenosyl methionine domain containing 1
SCAF8 SR-related CTD-associated factor 8
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35A5 solute carrier family 35, member A5
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNUPN snurportin 1
STX18 syntaxin 18
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TBC1D31 TBC1 domain family, member 31
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTC17 tetratricopeptide repeat domain 17
TWIST1 twist family bHLH transcription factor 1
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
WDR44 WD repeat domain 44
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZCCHC2 zinc finger, CCHC domain containing 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF165 zinc finger protein 165
ZNF33B zinc finger protein 33B