| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the harmine-5855 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP10B | ATPase, class V, type 10B |
| AURKC | aurora kinase C |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTBD18 | BTB (POZ) domain containing 18 |
| C2CD2L | C2CD2-like |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CBX5 | chromobox homolog 5 |
| CDK13 | cyclin-dependent kinase 13 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CREM | cAMP responsive element modulator |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTSF | cathepsin F |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EGR1 | early growth response 1 |
| FGF18 | fibroblast growth factor 18 |
| FST | follistatin |
| GNB2L1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
| GP6 | glycoprotein VI (platelet) |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GTF2I | general transcription factor IIi |
| HBS1L | HBS1-like translational GTPase |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXA11 | homeobox A11 |
| HOXB7 | homeobox B7 |
| IL16 | interleukin 16 |
| INHBA | inhibin, beta A |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KRT86 | keratin 86, type II |
| LEFTY1 | left-right determination factor 1 |
| LHX1 | LIM homeobox 1 |
| LMF2 | lipase maturation factor 2 |
| LOC157562 | uncharacterized LOC157562 |
| LOC257152 | uncharacterized LOC257152 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MED18 | mediator complex subunit 18 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MORC1 | MORC family CW-type zinc finger 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MUC1 | mucin 1, cell surface associated |
| MYH14 | myosin, heavy chain 14, non-muscle |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NGDN | neuroguidin, EIF4E binding protein |
| NRXN3 | neurexin 3 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| PCDHB12 | protocadherin beta 12 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PLD3 | phospholipase D family, member 3 |
| PLXNA2 | plexin A2 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRPF18 | pre-mRNA processing factor 18 |
| PRSS8 | protease, serine, 8 |
| PVR | poliovirus receptor |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RFPL3S | RFPL3 antisense |
| ROM1 | retinal outer segment membrane protein 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SCG5 | secretogranin V |
| SELPLG | selectin P ligand |
| SKIL | SKI-like proto-oncogene |
| SMC4 | structural maintenance of chromosomes 4 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| STATH | statherin |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TLE4 | transducin-like enhancer of split 4 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF500 | zinc finger protein 500 |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ACVR1 | activin A receptor, type I |
| ADRB2 | adrenoceptor beta 2, surface |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CENPE | centromere protein E, 312kDa |
| CEP70 | centrosomal protein 70kDa |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTPS1 | CTP synthase 1 |
| CUEDC1 | CUE domain containing 1 |
| CUTC | cutC copper transporter |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNMBP | dynamin binding protein |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FZD7 | frizzled class receptor 7 |
| GHR | growth hormone receptor |
| GID4 | GID complex subunit 4 |
| GPHN | gephyrin |
| GPR87 | G protein-coupled receptor 87 |
| H1F0 | H1 histone family, member 0 |
| HCFC2 | host cell factor C2 |
| HEATR3 | HEAT repeat containing 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| KIF20B | kinesin family member 20B |
| KIN | Kin17 DNA and RNA binding protein |
| KIZ | kizuna centrosomal protein |
| LOC730101 | uncharacterized LOC730101 |
| MAGEH1 | melanoma antigen family H1 |
| MCOLN1 | mucolipin 1 |
| MEIS1 | Meis homeobox 1 |
| MEPCE | methylphosphate capping enzyme |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MST1R | macrophage stimulating 1 receptor |
| MSX1 | msh homeobox 1 |
| MT1H | metallothionein 1H |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NAP1L3 | nucleosome assembly protein 1-like 3 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOL8 | nucleolar protein 8 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NSUN3 | NOP2/Sun domain family, member 3 |
| NVL | nuclear VCP-like |
| OFD1 | oral-facial-digital syndrome 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PEX2 | peroxisomal biogenesis factor 2 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PLAU | plasminogen activator, urokinase |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PXDC1 | PX domain containing 1 |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RBM12 | RNA binding motif protein 12 |
| RCOR3 | REST corepressor 3 |
| RNF121 | ring finger protein 121 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SCAF8 | SR-related CTD-associated factor 8 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SNUPN | snurportin 1 |
| STX18 | syntaxin 18 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TBC1D31 | TBC1 domain family, member 31 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TTC17 | tetratricopeptide repeat domain 17 |
| TWIST1 | twist family bHLH transcription factor 1 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) |
| WDR44 | WD repeat domain 44 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF33B | zinc finger protein 33B |