harmol-1750 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the harmol-1750 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
APOLD1 apolipoprotein L domain containing 1
ATG10 autophagy related 10
ATP10A ATPase, class V, type 10A
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP5SL ATP5S-like
ATR ATR serine/threonine kinase
BCAN brevican
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CCL23 chemokine (C-C motif) ligand 23
CDC25A cell division cycle 25A
CDK2 cyclin-dependent kinase 2
CDK6 cyclin-dependent kinase 6
CETN1 centrin, EF-hand protein, 1
CHAF1B chromatin assembly factor 1, subunit B (p60)
CLK1 CDC-like kinase 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CTRB2 chymotrypsinogen B2
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DDR1 discoidin domain receptor tyrosine kinase 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DUS2 dihydrouridine synthase 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPN2 epsin 2
EXOSC2 exosome component 2
FANCA Fanconi anemia, complementation group A
FASTK Fas-activated serine/threonine kinase
FEM1C fem-1 homolog c (C. elegans)
FGD1 FYVE, RhoGEF and PH domain containing 1
FSCN3 fascin actin-bundling protein 3, testicular
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GINS3 GINS complex subunit 3 (Psf3 homolog)
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
HFE hemochromatosis
HLA-DOA major histocompatibility complex, class II, DO alpha
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSF2 heat shock transcription factor 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL1RAP interleukin 1 receptor accessory protein
IPO5 importin 5
ITGA10 integrin, alpha 10
ITGB5 integrin, beta 5
KLHL12 kelch-like family member 12
KNTC1 kinetochore associated 1
KRT32 keratin 32, type I
KRT6B keratin 6B, type II
LGALS8 lectin, galactoside-binding, soluble, 8
LPAR3 lysophosphatidic acid receptor 3
MAML3 mastermind-like 3 (Drosophila)
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MBNL1 muscleblind-like splicing regulator 1
METAP2 methionyl aminopeptidase 2
MNS1 meiosis-specific nuclear structural 1
MST1 macrophage stimulating 1
NCAM1 neural cell adhesion molecule 1
NCAPH non-SMC condensin I complex, subunit H
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARD3 par-3 family cell polarity regulator
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PKP4 plakophilin 4
PRDM11 PR domain containing 11
PSG9 pregnancy specific beta-1-glycoprotein 9
PTK2 protein tyrosine kinase 2
RAB11B RAB11B, member RAS oncogene family
RARA retinoic acid receptor, alpha
RCAN1 regulator of calcineurin 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RHOT2 ras homolog family member T2
RPS2 ribosomal protein S2
RRP1B ribosomal RNA processing 1B
SBF1 SET binding factor 1
SEC31B SEC31 homolog B (S. cerevisiae)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC26A10 solute carrier family 26, member 10
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIDR scaffolding protein involved in DNA repair
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TCTN1 tectonic family member 1
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM194A transmembrane protein 194A
TMPRSS5 transmembrane protease, serine 5
UBE2O ubiquitin-conjugating enzyme E2O
USP34 ubiquitin specific peptidase 34
WDR61 WD repeat domain 61
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ACP6 acid phosphatase 6, lysophosphatidic
ADAP2 ArfGAP with dual PH domains 2
APOBR apolipoprotein B receptor
ASAP1-IT1 ASAP1 intronic transcript 1
AVEN apoptosis, caspase activation inhibitor
BATF3 basic leucine zipper transcription factor, ATF-like 3
BTK Bruton agammaglobulinemia tyrosine kinase
CAMTA2 calmodulin binding transcription activator 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHMP1A charged multivesicular body protein 1A
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CISH cytokine inducible SH2-containing protein
COQ3 coenzyme Q3 methyltransferase
CRTAP cartilage associated protein
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDC4 enhancer of mRNA decapping 4
EMD emerin
FAM188A family with sequence similarity 188, member A
FAM50B family with sequence similarity 50, member B
FAM63A family with sequence similarity 63, member A
FCHO1 FCH domain only 1
FMNL1 formin-like 1
FTSJ3 FtsJ homolog 3 (E. coli)
FURIN furin (paired basic amino acid cleaving enzyme)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GPN2 GPN-loop GTPase 2
GPR27 G protein-coupled receptor 27
H1FX H1 histone family, member X
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFI30 interferon, gamma-inducible protein 30
IL24 interleukin 24
ILK integrin-linked kinase
INO80D INO80 complex subunit D
IRF2 interferon regulatory factor 2
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
KPNA4 karyopherin alpha 4 (importin alpha 3)
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LSP1 lymphocyte-specific protein 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSRB1 methionine sulfoxide reductase B1
MT1E metallothionein 1E
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MTG1 mitochondrial ribosome-associated GTPase 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYBBP1A MYB binding protein (P160) 1a
NECAB3 N-terminal EF-hand calcium binding protein 3
NHEJ1 nonhomologous end-joining factor 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NQO2 NAD(P)H dehydrogenase, quinone 2
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PCTP phosphatidylcholine transfer protein
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLA2G12A phospholipase A2, group XIIA
PLIN3 perilipin 3
PNKP polynucleotide kinase 3'-phosphatase
PNPLA6 patatin-like phospholipase domain containing 6
POGLUT1 protein O-glucosyltransferase 1
PRR14L proline rich 14-like
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
QDPR quinoid dihydropteridine reductase
RABEPK Rab9 effector protein with kelch motifs
RNF19B ring finger protein 19B
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SAC3D1 SAC3 domain containing 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SETD1B SET domain containing 1B
SIRT6 sirtuin 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNX6 sorting nexin 6
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGS1 trimethylguanosine synthase 1
TOE1 target of EGR1, member 1 (nuclear)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRIM5 tripartite motif containing 5
TSEN34 TSEN34 tRNA splicing endonuclease subunit
UBE2M ubiquitin-conjugating enzyme E2M
UBP1 upstream binding protein 1 (LBP-1a)
UBXN8 UBX domain protein 8
UROS uroporphyrinogen III synthase
WBSCR16 Williams-Beuren syndrome chromosome region 16
XPOT exportin, tRNA
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF211 zinc finger protein 211
ZPR1 ZPR1 zinc finger