harmol-2900 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the harmol-2900 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM8 ADAM metallopeptidase domain 8
AEN apoptosis enhancing nuclease
APOC1 apolipoprotein C-I
AREG amphiregulin
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C11ORF16 chromosome 11 open reading frame 16
C19ORF66 chromosome 19 open reading frame 66
C21ORF2 chromosome 21 open reading frame 2
CA4 carbonic anhydrase IV
CA9 carbonic anhydrase IX
CD300C CD300c molecule
CDKL3 cyclin-dependent kinase-like 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CES3 carboxylesterase 3
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC2D C-type lectin domain family 2, member D
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CNPY4 canopy FGF signaling regulator 4
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DPP4 dipeptidyl-peptidase 4
DUSP10 dual specificity phosphatase 10
DUSP6 dual specificity phosphatase 6
ELP6 elongator acetyltransferase complex subunit 6
EMP3 epithelial membrane protein 3
ERP44 endoplasmic reticulum protein 44
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FBXL15 F-box and leucine-rich repeat protein 15
FBXL8 F-box and leucine-rich repeat protein 8
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FLOT1 flotillin 1
FOSL1 FOS-like antigen 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GGT1 gamma-glutamyltransferase 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR87 G protein-coupled receptor 87
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
JAM3 junctional adhesion molecule 3
KIAA0125 KIAA0125
KRT15 keratin 15, type I
LINC00216 long intergenic non-protein coding RNA 216
LMTK2 lemur tyrosine kinase 2
LOC157562 uncharacterized LOC157562
MAGOH2P mago-nashi homolog 2, pseudogene
MAPK7 mitogen-activated protein kinase 7
MERTK MER proto-oncogene, tyrosine kinase
METTL7A methyltransferase like 7A
MGAM maltase-glucoamylase
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MMP13 matrix metallopeptidase 13
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
N4BP2L2 NEDD4 binding protein 2-like 2
N4BP3 NEDD4 binding protein 3
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUMA1 nuclear mitotic apparatus protein 1
PIDD1 p53-induced death domain protein 1
PLK3 polo-like kinase 3
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD52 RAD52 homolog (S. cerevisiae)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RBPMS RNA binding protein with multiple splicing
RPL31 ribosomal protein L31
RSL1D1 ribosomal L1 domain containing 1
S100A9 S100 calcium binding protein A9
SESN1 sestrin 1
SETD1A SET domain containing 1A
SGSH N-sulfoglucosamine sulfohydrolase
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMIM7 small integral membrane protein 7
SRCAP Snf2-related CREBBP activator protein
SYNC syncoilin, intermediate filament protein
TM4SF1 transmembrane 4 L six family member 1
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TOP3A topoisomerase (DNA) III alpha
TRIB2 tribbles pseudokinase 2
UCN urocortin
UHRF1BP1L UHRF1 binding protein 1-like
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ALS2CL ALS2 C-terminal like
ARMCX5 armadillo repeat containing, X-linked 5
ASAP1-IT1 ASAP1 intronic transcript 1
ASIC3 acid sensing (proton gated) ion channel 3
ATAD5 ATPase family, AAA domain containing 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCNO cyclin O
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHML choroideremia-like (Rab escort protein 2)
CIC capicua transcriptional repressor
CLCF1 cardiotrophin-like cytokine factor 1
CLDN9 claudin 9
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CORT cortistatin
DDIT3 DNA-damage-inducible transcript 3
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DVL1 dishevelled segment polarity protein 1
EAF2 ELL associated factor 2
EHD3 EH-domain containing 3
ETV6 ets variant 6
EXTL2 exostosin-like glycosyltransferase 2
FAM110B family with sequence similarity 110, member B
FAM134B family with sequence similarity 134, member B
FAM169A family with sequence similarity 169, member A
FKBP5 FK506 binding protein 5
FOXK2 forkhead box K2
FZD2 frizzled class receptor 2
GAREM GRB2 associated, regulator of MAPK1
GK3P glycerol kinase 3 pseudogene
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HDAC11 histone deacetylase 11
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H4F histone cluster 1, H4f
HSPA2 heat shock 70kDa protein 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0513 KIAA0513
KIF13A kinesin family member 13A
LIN7B lin-7 homolog B (C. elegans)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP7D1 MAP7 domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN3 mucolipin 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MSX1 msh homeobox 1
MTCP1 mature T-cell proliferation 1
MYL5 myosin, light chain 5, regulatory
NLRX1 NLR family member X1
NOL12 nucleolar protein 12
OLFML3 olfactomedin-like 3
OSGIN1 oxidative stress induced growth inhibitor 1
PAQR3 progestin and adipoQ receptor family member III
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHF14 PHD finger protein 14
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS16 protease, serine, 16 (thymus)
PTPRU protein tyrosine phosphatase, receptor type, U
RAB3A RAB3A, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RBM4B RNA binding motif protein 4B
RCOR3 REST corepressor 3
SAYSD1 SAYSVFN motif domain containing 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC46A3 solute carrier family 46, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX12 SRY (sex determining region Y)-box 12
SP140L SP140 nuclear body protein-like
SPC25 SPC25, NDC80 kinetochore complex component
SSBP3 single stranded DNA binding protein 3
STX17 syntaxin 17
TASP1 taspase, threonine aspartase, 1
TCTA T-cell leukemia translocation altered
TCTN2 tectonic family member 2
TNRC6B trinucleotide repeat containing 6B
TP53BP1 tumor protein p53 binding protein 1
TUBA3C tubulin, alpha 3c
VASH1 vasohibin 1
VASH2 vasohibin 2
XK X-linked Kx blood group
YY2 YY2 transcription factor
ZDHHC11 zinc finger, DHHC-type containing 11
ZMYM3 zinc finger, MYM-type 3
ZNF165 zinc finger protein 165
ZNF204P zinc finger protein 204, pseudogene
ZNF37BP zinc finger protein 37B, pseudogene
ZNF532 zinc finger protein 532
ZNF639 zinc finger protein 639