| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the harmol-2900 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AEN | apoptosis enhancing nuclease |
| APOC1 | apolipoprotein C-I |
| AREG | amphiregulin |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CA4 | carbonic anhydrase IV |
| CA9 | carbonic anhydrase IX |
| CD300C | CD300c molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CES3 | carboxylesterase 3 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLEC2D | C-type lectin domain family 2, member D |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| DPP4 | dipeptidyl-peptidase 4 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP6 | dual specificity phosphatase 6 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EMP3 | epithelial membrane protein 3 |
| ERP44 | endoplasmic reticulum protein 44 |
| ESR1 | estrogen receptor 1 |
| FAS | Fas cell surface death receptor |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FLOT1 | flotillin 1 |
| FOSL1 | FOS-like antigen 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GGT1 | gamma-glutamyltransferase 1 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPR87 | G protein-coupled receptor 87 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| JAM3 | junctional adhesion molecule 3 |
| KIAA0125 | KIAA0125 |
| KRT15 | keratin 15, type I |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LMTK2 | lemur tyrosine kinase 2 |
| LOC157562 | uncharacterized LOC157562 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAPK7 | mitogen-activated protein kinase 7 |
| MERTK | MER proto-oncogene, tyrosine kinase |
| METTL7A | methyltransferase like 7A |
| MGAM | maltase-glucoamylase |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MMP13 | matrix metallopeptidase 13 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| N4BP3 | NEDD4 binding protein 3 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NPC1 | Niemann-Pick disease, type C1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PLK3 | polo-like kinase 3 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RPL31 | ribosomal protein L31 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| S100A9 | S100 calcium binding protein A9 |
| SESN1 | sestrin 1 |
| SETD1A | SET domain containing 1A |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SMIM7 | small integral membrane protein 7 |
| SRCAP | Snf2-related CREBBP activator protein |
| SYNC | syncoilin, intermediate filament protein |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TOP3A | topoisomerase (DNA) III alpha |
| TRIB2 | tribbles pseudokinase 2 |
| UCN | urocortin |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| ZNF652 | zinc finger protein 652 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL9 | B-cell CLL/lymphoma 9 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| CCNO | cyclin O |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIC | capicua transcriptional repressor |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN9 | claudin 9 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CORT | cortistatin |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DVL1 | dishevelled segment polarity protein 1 |
| EAF2 | ELL associated factor 2 |
| EHD3 | EH-domain containing 3 |
| ETV6 | ets variant 6 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FAM110B | family with sequence similarity 110, member B |
| FAM134B | family with sequence similarity 134, member B |
| FAM169A | family with sequence similarity 169, member A |
| FKBP5 | FK506 binding protein 5 |
| FOXK2 | forkhead box K2 |
| FZD2 | frizzled class receptor 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GK3P | glycerol kinase 3 pseudogene |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HDAC11 | histone deacetylase 11 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H4F | histone cluster 1, H4f |
| HSPA2 | heat shock 70kDa protein 2 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0513 | KIAA0513 |
| KIF13A | kinesin family member 13A |
| LIN7B | lin-7 homolog B (C. elegans) |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP7D1 | MAP7 domain containing 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCOLN3 | mucolipin 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MSX1 | msh homeobox 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NLRX1 | NLR family member X1 |
| NOL12 | nucleolar protein 12 |
| OLFML3 | olfactomedin-like 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PHF14 | PHD finger protein 14 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RBM4B | RNA binding motif protein 4B |
| RCOR3 | REST corepressor 3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP140L | SP140 nuclear body protein-like |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SSBP3 | single stranded DNA binding protein 3 |
| STX17 | syntaxin 17 |
| TASP1 | taspase, threonine aspartase, 1 |
| TCTA | T-cell leukemia translocation altered |
| TCTN2 | tectonic family member 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TP53BP1 | tumor protein p53 binding protein 1 |
| TUBA3C | tubulin, alpha 3c |
| VASH1 | vasohibin 1 |
| VASH2 | vasohibin 2 |
| XK | X-linked Kx blood group |
| YY2 | YY2 transcription factor |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF532 | zinc finger protein 532 |
| ZNF639 | zinc finger protein 639 |