| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the harpagoside-2935 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK4 | aarF domain containing kinase 4 |
| ADORA1 | adenosine A1 receptor |
| AQP9 | aquaporin 9 |
| ARMC4 | armadillo repeat containing 4 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CES3 | carboxylesterase 3 |
| CREM | cAMP responsive element modulator |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CYHR1 | cysteine/histidine-rich 1 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DMC1 | DNA meiotic recombinase 1 |
| DMWD | dystrophia myotonica, WD repeat containing |
| DSC3 | desmocollin 3 |
| DTNB | dystrobrevin, beta |
| EDNRA | endothelin receptor type A |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EXOC6B | exocyst complex component 6B |
| EXOSC2 | exosome component 2 |
| FAM110D | family with sequence similarity 110, member D |
| FDXR | ferredoxin reductase |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GLI3 | GLI family zinc finger 3 |
| GMPR | guanosine monophosphate reductase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GPX3 | glutathione peroxidase 3 |
| GRPR | gastrin-releasing peptide receptor |
| HDLBP | high density lipoprotein binding protein |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| ING2 | inhibitor of growth family, member 2 |
| ITGB4 | integrin, beta 4 |
| KRTAP2-4 | keratin associated protein 2-4 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRC1 | leucine rich repeat containing 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LTC4S | leukotriene C4 synthase |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MLXIP | MLX interacting protein |
| MTM1 | myotubularin 1 |
| NCS1 | neuronal calcium sensor 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NME8 | NME/NM23 family member 8 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PEX14 | peroxisomal biogenesis factor 14 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLSCR3 | phospholipid scramblase 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU5F1B | POU class 5 homeobox 1B |
| RAB26 | RAB26, member RAS oncogene family |
| RASA3 | RAS p21 protein activator 3 |
| RASAL2 | RAS protein activator like 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFPL3 | ret finger protein-like 3 |
| RHO | rhodopsin |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIX2 | SIX homeobox 2 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| TIMELESS | timeless circadian clock |
| TPSD1 | tryptase delta 1 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRIM14 | tripartite motif containing 14 |
| TRIM29 | tripartite motif containing 29 |
| UROD | uroporphyrinogen decarboxylase |
| YLPM1 | YLP motif containing 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| Symbol | Name |
|---|---|
| ACP6 | acid phosphatase 6, lysophosphatidic |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARMC6 | armadillo repeat containing 6 |
| ARRB1 | arrestin, beta 1 |
| ASGR2 | asialoglycoprotein receptor 2 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C14ORF159 | chromosome 14 open reading frame 159 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CD180 | CD180 molecule |
| CD320 | CD320 molecule |
| CFP | complement factor properdin |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CPTP | ceramide-1-phosphate transfer protein |
| CRY2 | cryptochrome circadian clock 2 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| ENO3 | enolase 3 (beta, muscle) |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FOXO4 | forkhead box O4 |
| GALE | UDP-galactose-4-epimerase |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPS2 | G protein pathway suppressor 2 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1T | histone cluster 1, H1t |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA1 | homeobox A1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIAA1024 | KIAA1024 |
| KIF24 | kinesin family member 24 |
| KLK5 | kallikrein-related peptidase 5 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MXD3 | MAX dimerization protein 3 |
| MYBBP1A | MYB binding protein (P160) 1a |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDE1 | nudE neurodevelopment protein 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PANK4 | pantothenate kinase 4 |
| PDGFD | platelet derived growth factor D |
| PDLIM1 | PDZ and LIM domain 1 |
| PGP | phosphoglycolate phosphatase |
| PIR | pirin (iron-binding nuclear protein) |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| QSER1 | glutamine and serine rich 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF122 | ring finger protein 122 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPRYD7 | SPRY domain containing 7 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| SYMPK | symplekin |
| SYNC | syncoilin, intermediate filament protein |
| TBC1D17 | TBC1 domain family, member 17 |
| TESK1 | testis-specific kinase 1 |
| THBS3 | thrombospondin 3 |
| THOP1 | thimet oligopeptidase 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM134 | transmembrane protein 134 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRABD | TraB domain containing |
| TRIM5 | tripartite motif containing 5 |
| TWF2 | twinfilin actin binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP19 | ubiquitin specific peptidase 19 |
| VILL | villin-like |
| VNN1 | vanin 1 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| ZNF408 | zinc finger protein 408 |
| ZNF428 | zinc finger protein 428 |
| ZNF493 | zinc finger protein 493 |
| ZNF580 | zinc finger protein 580 |
| ZNF695 | zinc finger protein 695 |
