| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the harpagoside-4981 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARTN | artemin |
| ASPH | aspartate beta-hydroxylase |
| ATG10 | autophagy related 10 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| B9D1 | B9 protein domain 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD82 | CD82 molecule |
| CEP41 | centrosomal protein 41kDa |
| CLDN11 | claudin 11 |
| CUL7 | cullin 7 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DUSP8 | dual specificity phosphatase 8 |
| EPHA1 | EPH receptor A1 |
| EPOR | erythropoietin receptor |
| FBLN1 | fibulin 1 |
| FCMR | Fc fragment of IgM receptor |
| FGFR4 | fibroblast growth factor receptor 4 |
| FMO5 | flavin containing monooxygenase 5 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR137 | G protein-coupled receptor 137 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HOMER3 | homer scaffolding protein 3 |
| HOXB3 | homeobox B3 |
| HOXC8 | homeobox C8 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IDS | iduronate 2-sulfatase |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL5RA | interleukin 5 receptor, alpha |
| ING2 | inhibitor of growth family, member 2 |
| ITGB7 | integrin, beta 7 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| MAL | mal, T-cell differentiation protein |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MXD3 | MAX dimerization protein 3 |
| NDRG2 | NDRG family member 2 |
| NF2 | neurofibromin 2 (merlin) |
| NFIB | nuclear factor I/B |
| NLE1 | notchless homolog 1 (Drosophila) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT1 | one cut homeobox 1 |
| PGR | progesterone receptor |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| RBM19 | RNA binding motif protein 19 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMC4 | structural maintenance of chromosomes 4 |
| STX7 | syntaxin 7 |
| TBX5 | T-box 5 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TLR5 | toll-like receptor 5 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPMT | thiopurine S-methyltransferase |
| TPSG1 | tryptase gamma 1 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRMT61A | tRNA methyltransferase 61A |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF3 | zinc finger protein 3 |
| ZNF609 | zinc finger protein 609 |
| ZNF771 | zinc finger protein 771 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| AFF4 | AF4/FMR2 family, member 4 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| APOD | apolipoprotein D |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CENPC | centromere protein C |
| CIC | capicua transcriptional repressor |
| CIDEC | cell death-inducing DFFA-like effector c |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DVL1 | dishevelled segment polarity protein 1 |
| EPPK1 | epiplakin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM222B | family with sequence similarity 222, member B |
| FANCE | Fanconi anemia, complementation group E |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FER | fer (fps/fes related) tyrosine kinase |
| FILIP1L | filamin A interacting protein 1-like |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD1 | FERM domain containing 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPR157 | G protein-coupled receptor 157 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXA4 | homeobox A4 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT140 | intraflagellar transport 140 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIZ | kizuna centrosomal protein |
| KRBOX4 | KRAB box domain containing 4 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MYF5 | myogenic factor 5 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPTX1 | neuronal pentraxin I |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OSMR | oncostatin M receptor |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| POM121 | POM121 transmembrane nucleoporin |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS16 | protease, serine, 16 (thymus) |
| PSKH1 | protein serine kinase H1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RGS20 | regulator of G-protein signaling 20 |
| RLN1 | relaxin 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| ROM1 | retinal outer segment membrane protein 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNHG20 | small nucleolar RNA host gene 20 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SREK1IP1 | SREK1-interacting protein 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STRN | striatin, calmodulin binding protein |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAOK1 | TAO kinase 1 |
| TBX19 | T-box 19 |
| TMEM212 | transmembrane protein 212 |
| TRAIP | TRAF interacting protein |
| TRIM16 | tripartite motif containing 16 |
| TRIM21 | tripartite motif containing 21 |
| UCN | urocortin |
| ULBP2 | UL16 binding protein 2 |
| WDR76 | WD repeat domain 76 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XYLT1 | xylosyltransferase I |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF329 | zinc finger protein 329 |
| ZNF442 | zinc finger protein 442 |
| ZNF574 | zinc finger protein 574 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
